[PDF] Computers In Systematic Biology eBook

Author : Andrew Hamilton
Publisher : Univ of California Press
Page : 320 pages
File Size : 18,26 MB
Release : 2013-11-09
Category : Science
ISBN : 0520956753

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The Evolution of Phylogenetic Systematics aims to make sense of the rise of phylogenetic systematics—its methods, its objects of study, and its theoretical foundations—with contributions from historians, philosophers, and biologists. This volume articulates an intellectual agenda for the study of systematics and taxonomy in a way that connects classification with larger historical themes in the biological sciences, including morphology, experimental and observational approaches, evolution, biogeography, debates over form and function, character transformation, development, and biodiversity. It aims to provide frameworks for answering the question: how did systematics become phylogenetic?

Author : Michael Schmitt
Publisher : BRILL
Page : 224 pages
File Size : 16,81 MB
Release : 2013-04-15
Category : Science
ISBN : 9004219293

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Biological Systematics has changed dramatically during the past 60 years from a handicraft or art to an accepted branch of science proper, due to the work of Willi Hennig, who was born in 1913. The scientific method of reconstructing phylogenetic relationships of organisms bases on Hennig's approach, the "Phylogenetic Systematics". The method is now so widely accepted and applied that it can firmly be regarded a paradigm, named 'cladistics'. In contrast, the life and personality of its founder is remarkably little known in the scientific community. The present book offers a detailed biography of Willi Hennig, and traces the roots of his thinking from his schooldays until his death in 1976. Some outstanding academic teachers and friends of his are introduced, too. The book offers an insight into the historical development of a 'scientific revolution', and highlights the life and the work of a 'cautious revolutioniser' in a Germany of dictatorship, war, and separation.

Author : Srinivas Aluru
Publisher : CRC Press
Page : 1108 pages
File Size : 27,77 MB
Release : 2005-12-21
Category : Computers
ISBN : 1420036270

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The enormous complexity of biological systems at the molecular level must be answered with powerful computational methods. Computational biology is a young field, but has seen rapid growth and advancement over the past few decades. Surveying the progress made in this multidisciplinary field, the Handbook of Computational Molecular Biology of

Author : James R. Valcourt
Publisher : Bloomsbury Publishing USA
Page : 289 pages
File Size : 17,11 MB
Release : 2017-02-07
Category : Science
ISBN : 1632860317

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A brilliant young scientist introduces us to the fascinating field that is changing our understanding of how the body works and the way we can approach healing. SYSTEMATIC is the first book to introduce general readers to systems biology, which is improving medical treatments and our understanding of living things. In traditional bottom-up biology, a biologist might spend years studying how a single protein works, but systems biology studies how networks of those proteins work together--how they promote health and how to remedy the situation when the system isn't functioning properly. Breakthroughs in systems biology became possible only when powerful computer technology enabled researchers to process massive amounts of data to study complete systems, and has led to progress in the study of gene regulation and inheritance, cancer drugs personalized to an individual's genetically unique tumor, insights into how the brain works, and the discovery that the bacteria and other microbes that live in the gut may drive malnutrition and obesity. Systems biology is allowing us to understand more complex phenomena than ever before. In accessible prose, SYSTEMATIC sheds light not only on how systems within the body work, but also on how research is yielding new kinds of remedies that enhance and harness the body's own defenses.

Author : Peter D. Olson
Publisher : Cambridge University Press
Page : 363 pages
File Size : 36,83 MB
Release : 2016-06-16
Category : Science
ISBN : 1107028582

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Cheap and plentiful genome sequence data is transforming biology, and will surely transform systematics. This volume explores how.

Author : National Research Council
Publisher : National Academies Press
Page : 469 pages
File Size : 32,23 MB
Release : 2006-01-01
Category : Science
ISBN : 030909612X

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Advances in computer science and technology and in biology over the last several years have opened up the possibility for computing to help answer fundamental questions in biology and for biology to help with new approaches to computing. Making the most of the research opportunities at the interface of computing and biology requires the active participation of people from both fields. While past attempts have been made in this direction, circumstances today appear to be much more favorable for progress. To help take advantage of these opportunities, this study was requested of the NRC by the National Science Foundation, the Department of Defense, the National Institutes of Health, and the Department of Energy. The report provides the basis for establishing cross-disciplinary collaboration between biology and computing including an analysis of potential impediments and strategies for overcoming them. The report also presents a wealth of examples that should encourage students in the biological sciences to look for ways to enable them to be more effective users of computing in their studies.

Author : Ran Libeskind-Hadas
Publisher : Cambridge University Press
Page : 289 pages
File Size : 13,64 MB
Release : 2014-09-22
Category : Science
ISBN : 1316061337

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Computing is revolutionizing the practice of biology. This book, which assumes no prior computing experience, provides students with the tools to write their own Python programs and to understand fundamental concepts in computational biology and bioinformatics. Each major part of the book begins with a compelling biological question, followed by the algorithmic ideas and programming tools necessary to explore it: the origins of pathogenicity are examined using gene finding, the evolutionary history of sex determination systems is studied using sequence alignment, and the origin of modern humans is addressed using phylogenetic methods. In addition to providing general programming skills, this book explores the design of efficient algorithms, simulation, NP-hardness, and the maximum likelihood method, among other key concepts and methods. Easy-to-read and designed to equip students with the skills to write programs for solving a range of biological problems, the book is accompanied by numerous programming exercises, available at www.cs.hmc.edu/CFB.