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Complex Systems Science in Biomedicine

Author : Thomas Deisboeck
Publisher : Springer Science & Business Media
Page : 857 pages
File Size : 10,11 MB
Release : 2007-06-13
Category : Medical
ISBN : 0387335323

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Complex Systems Science in Biomedicine Thomas S. Deisboeck and J. Yasha Kresh Complex Systems Science in Biomedicine covers the emerging field of systems science involving the application of physics, mathematics, engineering and computational methods and techniques to the study of biomedicine including nonlinear dynamics at the molecular, cellular, multi-cellular tissue, and organismic level. With all chapters helmed by leading scientists in the field, Complex Systems Science in Biomedicine's goal is to offer its audience a timely compendium of the ongoing research directed to the understanding of biological processes as whole systems instead of as isolated component parts. In Parts I & II, Complex Systems Science in Biomedicine provides a general systems thinking perspective and presents some of the fundamental theoretical underpinnings of this rapidly emerging field. Part III then follows with a multi-scaled approach, spanning from the molecular to macroscopic level, exemplified by studying such diverse areas as molecular networks and developmental processes, the immune and nervous systems, the heart, cancer and multi-organ failure. The volume concludes with Part IV that addresses methods and techniques driven in design and development by this new understanding of biomedical science. Key Topics Include: • Historic Perspectives of General Systems Thinking • Fundamental Methods and Techniques for Studying Complex Dynamical Systems • Applications from Molecular Networks to Disease Processes • Enabling Technologies for Exploration of Systems in the Life Sciences Complex Systems Science in Biomedicine is essential reading for experimental, theoretical, and interdisciplinary scientists working in the biomedical research field interested in a comprehensive overview of this rapidly emerging field. About the Editors: Thomas S. Deisboeck is currently Assistant Professor of Radiology at Massachusetts General Hospital and Harvard Medical School in Boston. An expert in interdisciplinary cancer modeling, Dr. Deisboeck is Director of the Complex Biosystems Modeling Laboratory which is part of the Harvard-MIT Martinos Center for Biomedical Imaging. J. Yasha Kresh is currently Professor of Cardiothoracic Surgery and Research Director, Professor of Medicine and Director of Cardiovascular Biophysics at the Drexel University College of Medicine. An expert in dynamical systems, he holds appointments in the School of Biomedical Engineering and Health Systems, Dept. of Mechanical Engineering and Molecular Pathobiology Program. Prof. Kresh is Fellow of the American College of Cardiology, American Heart Association, Biomedical Engineering Society, American Institute for Medical and Biological Engineering.

Complex Sciences

Author : Jie Zhou
Publisher : Springer Science & Business Media
Page : 1267 pages
File Size : 32,27 MB
Release : 2009-06-29
Category : Computers
ISBN : 3642024696

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I was invited to join the Organizing Committee of the First International Conference on Complex Sciences: Theory and Applications (Complex 2009) as its ninth member. At that moment, eight distinguished colleagues, General Co-chairs Eugene Stanley and Gaoxi Xiao, Technical Co-chairs J·nos Kertész and Bing-Hong Wang, Local Co-chairs Hengshan Wang and Hong-An Che, Publicity Team Shi Xiao and Yubo Wang, had spent hundreds of hours pushing the conference half way to its birth. Ever since then, I have been amazed to see hundreds of papers flooding in, reviewed and commented on by the TPC members. Finally, more than 200 contributions were - lected for the proceedings currently in your hands. They include about 200 papers from the main conference (selected from more than 320 submissions) and about 33 papers from the five collated workshops: Complexity Theory of Art and Music (COART) Causality in Complex Systems (ComplexCCS) Complex Engineering Networks (ComplexEN) Modeling and Analysis of Human Dynamics (MANDYN) Social Physics and its Applications (SPA) Complex sciences are expanding their colonies at such a dazzling speed that it - comes literally impossible for any conference to cover all the frontiers.

Philosophy of Complex Systems

Author :
Publisher : Elsevier
Page : 951 pages
File Size : 18,68 MB
Release : 2011-05-23
Category : Mathematics
ISBN : 0080931227

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The domain of nonlinear dynamical systems and its mathematical underpinnings has been developing exponentially for a century, the last 35 years seeing an outpouring of new ideas and applications and a concomitant confluence with ideas of complex systems and their applications from irreversible thermodynamics. A few examples are in meteorology, ecological dynamics, and social and economic dynamics. These new ideas have profound implications for our understanding and practice in domains involving complexity, predictability and determinism, equilibrium, control, planning, individuality, responsibility and so on.Our intention is to draw together in this volume, we believe for the first time, a comprehensive picture of the manifold philosophically interesting impacts of recent developments in understanding nonlinear systems and the unique aspects of their complexity. The book will focus specifically on the philosophical concepts, principles, judgments and problems distinctly raised by work in the domain of complex nonlinear dynamical systems, especially in recent years. -Comprehensive coverage of all main theories in the philosophy of Complex Systems -Clearly written expositions of fundamental ideas and concepts -Definitive discussions by leading researchers in the field -Summaries of leading-edge research in related fields are also included

Principles of Systems Science

Author : George E. Mobus
Publisher : Springer
Page : 782 pages
File Size : 19,52 MB
Release : 2014-11-10
Category : Science
ISBN : 1493919202

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This pioneering text provides a comprehensive introduction to systems structure, function, and modeling as applied in all fields of science and engineering. Systems understanding is increasingly recognized as a key to a more holistic education and greater problem solving skills, and is also reflected in the trend toward interdisciplinary approaches to research on complex phenomena. While the concepts and components of systems science will continue to be distributed throughout the various disciplines, undergraduate degree programs in systems science are also being developed, including at the authors’ own institutions. However, the subject is approached, systems science as a basis for understanding the components and drivers of phenomena at all scales should be viewed with the same importance as a traditional liberal arts education. Principles of Systems Science contains many graphs, illustrations, side bars, examples, and problems to enhance understanding. From basic principles of organization, complexity, abstract representations, and behavior (dynamics) to deeper aspects such as the relations between information, knowledge, computation, and system control, to higher order aspects such as auto-organization, emergence and evolution, the book provides an integrated perspective on the comprehensive nature of systems. It ends with practical aspects such as systems analysis, computer modeling, and systems engineering that demonstrate how the knowledge of systems can be used to solve problems in the real world. Each chapter is broken into parts beginning with qualitative descriptions that stand alone for students who have taken intermediate algebra. The second part presents quantitative descriptions that are based on pre-calculus and advanced algebra, providing a more formal treatment for students who have the necessary mathematical background. Numerous examples of systems from every realm of life, including the physical and biological sciences, humanities, social sciences, engineering, pre-med and pre-law, are based on the fundamental systems concepts of boundaries, components as subsystems, processes as flows of materials, energy, and messages, work accomplished, functions performed, hierarchical structures, and more. Understanding these basics enables further understanding both of how systems endure and how they may become increasingly complex and exhibit new properties or characteristics. Serves as a textbook for teaching systems fundamentals in any discipline or for use in an introductory course in systems science degree programs Addresses a wide range of audiences with different levels of mathematical sophistication Includes open-ended questions in special boxes intended to stimulate integrated thinking and class discussion Describes numerous examples of systems in science and society Captures the trend towards interdisciplinary research and problem solving

Untangling Complex Systems

Author : Pier Luigi Gentili
Publisher : CRC Press
Page : 553 pages
File Size : 26,61 MB
Release : 2018-09-03
Category : Mathematics
ISBN : 0429847548

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Complex Systems are natural systems that science is unable to describe exhaustively. Examples of Complex Systems are both unicellular and multicellular living beings; human brains; human immune systems; ecosystems; human societies; the global economy; the climate and geology of our planet. This book is an account of a marvelous interdisciplinary journey the author made to understand properties of the Complex Systems. He has undertaken his trip, equipped with the fundamental principles of physical chemistry, in particular, the Second Law of Thermodynamics that describes the spontaneous evolution of our universe, and the tools of Non-linear dynamics. By dealing with many disciplines, in particular, chemistry, biology, physics, economy, and philosophy, the author demonstrates that Complex Systems are intertwined networks, working in out-of-equilibrium conditions, which exhibit emergent properties, such as self-organization phenomena and chaotic behaviors in time and space.

The Complex Alternative

Author : David C. Krakauer
Publisher :
Page : pages
File Size : 28,33 MB
Release : 2021-11
Category :
ISBN : 9781947864405

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What Is a Complex System?

Author : James Ladyman
Publisher : Yale University Press
Page : 182 pages
File Size : 23,86 MB
Release : 2020-08-05
Category : Computational complexity
ISBN : 0300251106

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A clear, concise introduction to the quickly growing field of complexity science that explains its conceptual and mathematical foundations What is a complex system? Although "complexity science" is used to understand phenomena as diverse as the behavior of honeybees, the economic markets, the human brain, and the climate, there is no agreement about its foundations. In this introduction for students, academics, and general readers, philosopher of science James Ladyman and physicist Karoline Wiesner develop an account of complexity that brings the different concepts and mathematical measures applied to complex systems into a single framework. They introduce the different features of complex systems, discuss different conceptions of complexity, and develop their own account. They explain why complexity science is so important in today's world.

Dynamics Of Complex Systems

Author : Yaneer Bar-yam
Publisher : CRC Press
Page : 866 pages
File Size : 36,86 MB
Release : 2019-03-04
Category : Mathematics
ISBN : 0429717598

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This book aims to develop models and modeling techniques that are useful when applied to all complex systems. It adopts both analytic tools and computer simulation. The book is intended for students and researchers with a variety of backgrounds.

Complex Sciences

Author : Kristin Glass
Publisher : Springer
Page : 350 pages
File Size : 26,44 MB
Release : 2013-11-08
Category : Computers
ISBN : 3319034731

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This book constitutes the thoroughly refereed post-conference proceedings of the Second International ICST Conference on Complex Sciences, COMPLEX 2012, held in Santa Fe, New Mexico, USA in December 2012. The 29 revised full papers presented were carefully reviewed and selected from various submissions. The papers cover aspects on foundations and analysis of complex systems, complex biological systems, complex social systems, complex engineering systems.