[PDF] Collaborative Genomics Projects A Comprehensive Guide eBook

Author : Margi Sheth
Publisher : Academic Press
Page : 146 pages
File Size : 10,76 MB
Release : 2016-02-24
Category : Science
ISBN : 0128023686

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Collaborative Genomics Projects: A Comprehensive Guide contains operational procedures, policy considerations, and the many lessons learned by The Cancer Genome Atlas Project. This book guides the reader through methods in patient sample acquisition, the establishment of data generation and analysis pipelines, data storage and dissemination, quality control, auditing, and reporting. This book is essential for those looking to set up or collaborate within a large-scale genomics research project. All authors are contributors to The Cancer Genome Atlas (TCGA) Program, a NIH- funded effort to generate a comprehensive catalog of genomic alterations in more than 35 cancer types. As the cost of genomic sequencing is decreasing, more and more researchers are leveraging genomic data to inform the biology of disease. The amount of genomic data generated is growing exponentially, and protocols need to be established for the long-term storage, dissemination, and regulation of this data for research. The book's authors create a complete handbook on the management of research projects involving genomic data as learned through the evolution of the TCGA program, a project that was primarily carried out in the US, but whose impact and lessons learned can be applied to international audiences. Establishes a framework for managing large-scale genomic research projects involving multiple collaborators Describes lessons learned through TCGA to prepare for potential roadblocks Evaluates policy considerations that are needed to avoid pitfalls Recommends strategies to make project management more efficient

Author : Dr. Spineanu Eugenia
Publisher : Dr. Spineanu Eugenia
Page : 362 pages
File Size : 25,81 MB
Release :
Category : Medical
ISBN :

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Are you or a loved one facing the challenges of thymic tumors? Discover hope, empowerment, and expert guidance in "Thymic Tumors Unveiled: A Comprehensive Guide to Diagnosis, Treatment, and Hope." This comprehensive treatise offers a lifeline to those navigating the rare and complex world of thymic tumors. From understanding the disease's origins, anatomy, and genetic factors to exploring cutting-edge treatments and the latest in precision medicine, this book covers it all. Inside, you'll find: In-Depth Knowledge: Dive into the intricacies of thymic tumors, from their historical perspective to the latest research breakthroughs. Understand the anatomy of the thymus gland, the role of genetics, and the influence of environmental factors. Cutting-Edge Therapies: Explore the future of thymic tumor treatment with precision medicine, immunotherapies, and targeted therapies. Learn how advancements in molecular diagnostics are reshaping the landscape of care. Patient-Centered Care: Discover how patient advocacy groups and support networks offer invaluable resources, emotional support, and insights to navigate the thymic tumor journey. Global Access to Care: Learn about the vision for equitable access to thymic tumor care, breaking down geographical barriers and promoting international collaboration. Data-Driven Insights: Explore the role of data-driven decision-making, predictive analytics, and real-world evidence in shaping the future of thymic tumor management. "Thymic Tumors Unveiled" is more than a book; it's a beacon of hope for patients and their families. With clear and accessible language, this treatise empowers you to become an informed advocate for your health, guiding you towards better outcomes and improved quality of life. Join the global movement towards a brighter future for thymic tumor patients. Whether you're a healthcare professional, a patient, or a caregiver, this treatise offers essential knowledge, inspiration, and a vision for a world where thymic tumors are better understood, treated, and ultimately conquered.

Author : Susan L. Speaker
Publisher : Chemical Heritage Foundation
Page : 44 pages
File Size : 18,12 MB
Release : 1993
Category : Science
ISBN : 9780941901109

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This simple, concise introduction to the HGP for the general reader explores the origins of the genome project and reactions in the scientific community; important technologies and techniques; institutions connected with the HGP, including designated genome centers, important suppliers of resources, and corporations; systems of communication; and ethical, legal, and social issues. A publication of the Biomolecular Sciences Initiative of CHF's Beckman Center for the History of Chemistry.

Author : Cecilia Saccone
Publisher : John Wiley & Sons
Page : 442 pages
File Size : 41,79 MB
Release : 2005-03-11
Category : Science
ISBN : 0471326410

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This comprehensive reference covers the comparative methodologyinvolved in studying molecular evolution. Providing a practicalintroduction to the role of bioinformatics in comparative genomics,this publication further discusses the basic technology used ingenome sequencing projects and provides an overview of genomestorage databases currently in use. This timely and cutting-edge text also: Reviews the basic principles of genomics and gene expressionanalysis Discusses analytic methods in proteomics andtranscriptomics Includes a comprehensive list of Web resource

Author : Dan J. Stein
Publisher : Academic Press
Page : 310 pages
File Size : 41,85 MB
Release : 2020-01-17
Category : Psychology
ISBN : 0128150637

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Global Mental Health and Neuroethics explores conceptual, ethical and clinical issues that have emerged with the expansion of clinical neuroscience into middle- and low-income countries. Conceptual issues covered include avoiding scientism and skepticism in global mental health, integrating evidence-based and value-based global medicine, and developing a welfarist approach to the practice of global psychiatry. Ethical issues addressed include those raised by developments in neurogenetics, cosmetic psychopharmacology and deep brain stimulation. Perspectives drawing on global mental health and neuroethics are used to explore a number of different clinical disorders and developmental stages, ranging from childhood through to old age. Synthesizes existing work at the intersection of global mental health and neuroethics Presents the work of leading practitioners of global mental health and neuroethics who address clinical issues Looks at clinical decision-making in settings with non-Western values and customs Covers patient empowerment, human rights, cognitive enhancement, and more

Author : Sahra Gibbon
Publisher : Routledge
Page : 474 pages
File Size : 15,46 MB
Release : 2018-04-17
Category : Science
ISBN : 1315451670

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The Handbook provides an essential resource at the interface of Genomics, Health and Society, and forms a crucial research tool for both new students and established scholars across biomedicine and social sciences. Building from and extending the first Routledge Handbook of Genetics and Society, the book offers a comprehensive introduction to pivotal themes within the field, an overview of the current state of the art knowledge on genomics, science and society, and an outline of emerging areas of research. Key themes addressed include the way genomic based DNA technologies have become incorporated into diverse arenas of clinical practice and research whilst also extending beyond the clinic; the role of genomics in contemporary ‘bioeconomies’; how challenges in the governance of medical genomics can both reconfigure and stabilise regulatory processes and jurisdictional boundaries; how questions of diversity and justice are situated across different national and transnational terrains of genomic research; and how genomics informs – and is shaped by – developments in fields such as epigenetics, synthetic biology, stem cell, microbial and animal model research. Chapters 13 and 28 of this book are freely available as downloadable Open Access PDFs at http://www.taylorfrancis.com, under a Creative Commons Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND) 4.0 license.

Author : Jennifer B. Mccormick
Publisher : Academic Press
Page : 232 pages
File Size : 38,23 MB
Release : 2022-11-29
Category : Medical
ISBN : 0128198044

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Genomic Data Sharing: Case Studies, Challenges, and Opportunities for Precision Medicine provides a comprehensive overview of current and emerging issues in genomic data sharing. In this book, international leaders in genomic data examine these issues in-depth, offering practical case studies that highlight key successes, challenges and opportunities. Sections discuss the eMERGE Network, Undiagnosed Disease Network, Vanderbilt Biobank, Marshfield Clinic Biobank, Minnesota Authorization, Rochester Epidemiology Project, NIH sponsored biobanks, GINA, and Global Alliance for Genomics and Health (GA4GH). In addition to these perspectives from the frontlines, the book also provides succinct overviews of ethical, legal, social and IT challenges. Clinician investigators, clinicians affiliated with academic medical centers, policymakers and regulators will also gain insights that will allow them to navigate the increasingly complex ethical, social and clinical landscape of genomic data sharing. Covers both technical and ELSI (ethical, legal, and social implications) perspectives on genomic data sharing Includes applied case studies of existing genomic data sharing consortia, including the eMERGE Network, Undiagnosed Disease Network, and the Global Alliance for Genomics and Health (GA4GH), among others Features chapter contributions from international leaders in genomic data sharing

Author :
Publisher : Cybellium
Page : 226 pages
File Size : 31,89 MB
Release :
Category : Science
ISBN : 1836790473

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Welcome to the forefront of knowledge with Cybellium, your trusted partner in mastering the cutting-edge fields of IT, Artificial Intelligence, Cyber Security, Business, Economics and Science. Designed for professionals, students, and enthusiasts alike, our comprehensive books empower you to stay ahead in a rapidly evolving digital world. * Expert Insights: Our books provide deep, actionable insights that bridge the gap between theory and practical application. * Up-to-Date Content: Stay current with the latest advancements, trends, and best practices in IT, Al, Cybersecurity, Business, Economics and Science. Each guide is regularly updated to reflect the newest developments and challenges. * Comprehensive Coverage: Whether you're a beginner or an advanced learner, Cybellium books cover a wide range of topics, from foundational principles to specialized knowledge, tailored to your level of expertise. Become part of a global network of learners and professionals who trust Cybellium to guide their educational journey. www.cybellium.com

Author : VIRUTI SHIVAN
Publisher : Viruti Satyan Shivan
Page : 221 pages
File Size : 47,63 MB
Release :
Category : Science
ISBN :

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Dive into the groundbreaking realm of bioinformatics with "Bioinformatics Scientist- The Comprehensive Guide," your ultimate resource for mastering the intricacies of biological data analysis. This guide demystifies the complex world of genetic codes, protein databases, and computational biology, providing an unparalleled journey into the heart of modern biology. Without the need for images or illustrations, the book focuses purely on the rich, detailed narrative and insightful analyses, ensuring an engaging and immersive reading experience. Whether you're a budding scientist, a seasoned researcher, or simply a curious mind, this book promises to transform your understanding of biology, offering a fresh perspective on how data can unlock the mysteries of life itself. In an era where information is abundant yet clarity is scarce, this comprehensive guide stands out by not only covering the technical aspects of bioinformatics but also by connecting the dots between computational techniques and their real-world applications in solving biological problems. Through vivid hypothetical scenarios and personal anecdotes from experts in the field, readers are taken on a captivating journey from the basics of DNA sequencing to the forefront of genetic research. The book emphasizes the critical role of bioinformatics in advancing healthcare, environmental conservation, and our understanding of evolution, making it an essential addition to the library of anyone looking to make a mark in the biological sciences.

Author : Dr. Spineanu Eugenia
Publisher : Dr. Spineanu Eugenia
Page : 243 pages
File Size : 28,31 MB
Release : 2024-03-03
Category : Cooking
ISBN :

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"Diabetes Unveiled: A Comprehensive Guide to Understanding, Management, and Future Directions" is an exhaustive exploration into the multifaceted world of diabetes, a condition that affects millions globally. This treatise delves deep into the biological underpinnings of the disease, from the intricacies of pancreatic function to the complexities of hormonal regulation. It sheds light on the symptoms, diagnostic criteria, and the various stages of diabetes, providing invaluable insights for both patients and healthcare professionals. The guide also discusses the myriad complications associated with diabetes, from microvascular to neuropathic issues, offering a holistic view of the challenges faced by those with the condition. Beyond the medical aspects, this work delves into the socio-cultural and economic dimensions of diabetes, addressing the disparities in healthcare access, the influence of cultural beliefs on health behaviors, and the economic burden of the disease on societies. It emphasizes the importance of patient narratives, community-based interventions, and the role of schools and workplaces in managing and preventing diabetes. In its concluding sections, the treatise looks to the future, discussing the latest in technological advancements, the potential of stem cell research, and the emerging role of artificial intelligence in diabetes care. It also touches upon the ethical considerations in diabetes research, ensuring a well-rounded understanding of the subject. "Diabetes Unveiled" stands as a testament to the ever-evolving understanding of diabetes, serving as an essential resource for all stakeholders in the fight against this global health challenge.