[PDF] Clinical Neurotoxicology eBook

Author : Michael R. Dobbs
Publisher : Elsevier Health Sciences
Page : 729 pages
File Size : 34,8 MB
Release : 2009-01-01
Category : Medical
ISBN : 0323052606

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Clinical Neurotoxicology offers accurate, relevant, and comprehensive coverage of a field that has grown tremendously in the last 20 years. You'll get a current symptomatic approach to treating disorders caused by neurotoxic agents, environmental factors-such as heavy metals and pesticides-and more. Apply discussions of cellular and molecular processes and pathology to clinical neurology. Leading authorities and up-and-coming clinical neurotoxicologists present their expertise on wide-ranging, global subjects and debate controversies in the specialty, including Gulf War Syndrome. And, Expert Consult functionality allows you to access the full text of the book online, from any Internet connection. Provides a complete listing of neurotoxic agents-from manufactured to environmental-so you get comprehensive, clinical coverage. Covers how toxins manifest themselves according to age and co-morbidity so that you can address the needs of all your patients. Offers broad and in-depth coverage of toxins from all over the world through contributions by leading authorities and up-and-coming clinical neurotoxicologists. Features discussion of controversial and unusual topics such as Gulf War Syndrome, Parkinson's Disease, motor neuron disease, as well as other issues that are still in question. Includes access to www.expertconsult.com, a companion website where you can quickly search the complete contents of the book. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should online access to the web site be discontinued.

Author :
Publisher : Elsevier
Page : 546 pages
File Size : 27,55 MB
Release : 2015-11-09
Category : Medical
ISBN : 044462628X

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Occupational Neurology a volume in the Handbook of Clinical Neurology Series, provides a comprehensive overview of the science, clinical diagnosis, and treatment for neurotoxin related neurological and psychiatric disorders. This timely collection provides not only a complete scientific reference on the chemical origin of this class of neurological and psychiatric disorders, but also a practical guide to diagnosis and treatment challenges and best practices. Handbook of Clinical Neurology Series The first volume of the Handbook of Clinical Neurology under the editorship of George Bruyn and Pierre Vinken was published in 1968. In 1982, the series was brought to an interim conclusion with the publication of the cumulative index volume (Volume 44). By that stage, the Handbook had come to represent one of the largest scientific works ever published. It enjoys a high reputation in specialist media circles throughout the world. After the series was concluded in 1982, it was realized that an update of the material was imperative. Accordingly, a revised series was planned and published over the following years, concluding with the publication of another cumulative index to both series (Volume 76-78) in 2002. Since then, George Bruyn has passed away and Pierre Vinken has retired, but the need for a further new series, incorporating advances in the field, again become necessary. Professors Michael J. Aminoff, François Boller and Dick F. Swaab have with enthusiasm taken on the responsibility of supervising the preparation of a third series, the first volumes of which were published in 2003. Now, more than 130 volumes after the first published, the Handbook of Clinical Neurology series continues to have an unparalleled reputation for providing the latest foundational research, diagnosis, and treatment protocols essential for both basic neuroscience research and clinical neurology. Provides comprehensive coverage of neurotoxins, especially in the workplace Details the latest science as the foundation for neurotoxicity diagnosis and treatment Presents coverage of the diagnosis and treatment essential for clinical neurologists and occupational medicine specialists

Author : Peter S. Spencer
Publisher :
Page : 956 pages
File Size : 22,40 MB
Release : 1980
Category : Nervous system
ISBN :

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Two decades have passed since publication of the first edition of Experimental and Clinical Neurotoxicology pioneered the development of this discipline. Since then no other book has approached the breadth, scholarship, and balance of that landmark volume. For this long-awaited second edition, the original editors have been joined by Albert Ludolf, who brings expertise in biological neurotoxicology, and together with their distinguished contributors they have completely rewritten and reorganized the text.The scientific and clinical foundation is laid in three comprehensive introductory chapters. An overview of the biological basis of neurotoxicity provides the goundwork for discussing the scope of human and veterinary neurotoxic disease.The bulk of the text is devoted to an alphabetical treatment of chemicals with neurotoxic potential. This consists of tightly written overviews of the properties, actions, and mechanisms of all manner of substances, whether natural or synthetic. The neurotoxic side effects of experimental agents and of therapeutic as well as abused drugs are covered extensively. Environmental pollutants, workplace contaminants, personal-use products, food additives, and agents harbored by plants, animals, and humans for use against their respective enemies are discussed. Each substance is rated on a three-point scale for the weight of evidence indicating a specific neurotoxic effect in humans, animals, or laboratory models. These effects are summarized and cross-referenced in a series of appendices and an extensive index.In summary, the second edition establishes neurotoxicology as a scientific discipline that melds neurobiology, toxicology, and neurology. From this unique vantage point, the book examines in encyclopedic manner several hundred chemicals with the capacity to induce neurological illness in humans and animals. Indispensable for the experimental neuroscientist and toxicologist, as well as for practitioners of human and animal medicine, the book also provides an authoritative, critical, and pithy reference work for specialists in public health and the legal profession.

Author : Louis W. Chang
Publisher : Elsevier
Page : 875 pages
File Size : 15,56 MB
Release : 1995-04-20
Category : Science
ISBN : 0080537472

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Neurotoxicology: Approaches and Methods provides a unique and comprehensive presentation of the current concepts and state-of-the-art methods for the assessment of neurotoxicity. The book analyzes various techniques available and discusses their strengths and weaknesses. This volume will serve as an excellent desk companion and laboratory guide for all investigators, researchers, clinicians, and students interested in neurotoxicology. The internationally knowngroup of editors divide the book into seven sections: Neuromorphological and Neuropathological Approaches; Neurophysiological Approaches; Neurobehavioral Toxicology; Neurochemical and Biomolecular Approaches; In-Vitro Models; Clinical Neurotoxicology; and Risk Assessment of Neurotoxicity. Each section yields the most up-to-date information by experts in their fields. Meticulously organized and edited, Neurotoxicology: Approaches and Methods is the most authoritative and well-planned neurotoxicology book on the market. Discusses neurobehavioral testing methods for assessment of neural dysfunctions Explains state-of-the-art diagnostic methods, such as clinico-neuropsychological and neurophysiological methods, for patients confronted by neurotoxic problems Discusses In Vitro methods, including aggregating brain cell methods, organotypic cultures, and the use of human neuronal cell lines for the assessment of neurotoxicity Presents step-by-step procedures for many methods Provides state-of-the-art neuromorphological and biomolecular methods and approaches for neurotoxicity investigation

Author :
Publisher : Academic Press
Page : 330 pages
File Size : 29,86 MB
Release : 2022-07-24
Category : Medical
ISBN : 0128191775

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Occupational Neurotoxicology, Volume Seven covers neurotoxicants and exposures to a variety of hazards in the workplace and how they can affect nervous functions in different ways. Metals and organic compounds, both at high level acute exposure and long-term low-level exposure can affect motor functions, cognition, behavior and neurosensory functions. Sections cover Oil leakage in aircraft, aerotoxic syndrome, Organic solvents, WTC neurotoxicities, Environmental intolerance, Pesticides, Carbon monoxide, Mercury Neurotoxicity in Gold Miners, and the Current evolution of neurobehavioral methods. Provides updated information about exposure and neurotoxic outcomes Includes indication on new tools for neurobehavioral assessment Covers practical indications on preventive aspects

Author : Edward J. Massaro
Publisher : Springer Science & Business Media
Page : 599 pages
File Size : 36,99 MB
Release : 2002-03-20
Category : Medical
ISBN : 1592591655

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N eurotoxicology is a broad and burgeoning field of research. Its growth in recent years can be related, in part, to increased interest in and concern with the fact that a growing number of anthropogenic agents with neurotoxic potential, including pesticides, 1ead, mercury, and the polytypic byproducts of combustion and industrial production, continue to be spewed into and accumulate in the environment. In addition, there is great interest in natural products, including toxins, as sources of therapeutic agents. Indeed, it is well known that many natural toxins ofbroadly differing structure, produced or accumulated for predatory or defensive purposes, and toxic agents, accumulated incidentalIy by numerous species, function to perturb nervous tissue. Components of some of these toxins have been shown to be useful therapeutic agents and/or research reagents. Unfor of some neurotoxicants of anthropogenic ori tunately, the environmental accumulation gin, expecialIy pesticides and metals, has resulted in incidents ofhuman poisoning, some of epidemic proportion, and high levels of morbidity and mortality. Furthermore, an increasing incidence of neurobehavioral disorders, some with baffling symptoms, is confronting clinicians. It is not clear whether this is merely the re suit of increased vigi lance and/or improved diagnostics or a consequence of improved health care. In any case, the role of exposure to environmental and occupational neurotoxicants in the etiology of these phenomena, as well as neurodegenerative diseases, is coming under increasing scrutiny and investigation.

Author : William Slikker Jr.
Publisher : Elsevier
Page : 767 pages
File Size : 41,44 MB
Release : 1998-08-10
Category : Science
ISBN : 0080533434

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The Handbook of Developmental Neurotoxicology provides a comprehensive account of the impacts, mechanisms, and clinical relevances of chemicals on the development of the nervous system. The book is written by internationally recognized experts on developmental neurotoxicology, covering subjects from basic neuro-development to toxic syndromes induced by various chemicals. It is an important text for both students and professionals who are interested in developmental neurobiology and neurotoxicology. Written by internationally recognized experts on developmental neurotoxicology Includes extensive references Well illustrated with diagrams, charts and tables Provides coverage of basic neurobiology as well as neurotoxicology

Author : Michael R. Dobbs
Publisher : Saunders
Page : 0 pages
File Size : 21,26 MB
Release : 2011
Category : Medical
ISBN : 9781455711116

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This issue of Neurologic Clinics addresses the neurologic consequences of exposure to environmental toxins.

Author : Mohamed B. Abou-Donia
Publisher : CRC Press
Page : 642 pages
File Size : 35,25 MB
Release : 1992-07-15
Category : Medical
ISBN : 9781439805428

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Neurotoxicology provides a thorough understanding of neurotoxicology through its integration of multilateral ideas covering several disciplines, including chemistry, biochemistry, anatomy, physiology, and pathology. It discusses neurotoxic agents, describes the methods for studying neurotoxic actions, covers factors affecting neurotoxicity, and inc