[PDF] Clinical Applications Of Neurotrophic Factors eBook

Author : Gregory R. Bock
Publisher : John Wiley & Sons
Page : 264 pages
File Size : 32,97 MB
Release : 2008-04-30
Category : Medical
ISBN : 0470514876

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Degeneration of sensory receptors or of the nerves innervating them leads to a sensory deficit. Various strategies have been tried for promoting regrowth of sensory receptors, particularly in the eye and ear. The latest data from experimental studies in animals are presented in the book including applications of BDNF and CNTF in the eye and epidermal growth factor in the ear.

Author : Jeffrey Kordower
Publisher : Elsevier
Page : 523 pages
File Size : 31,74 MB
Release : 2011-04-28
Category : Medical
ISBN : 0080556981

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This second edition of CNS Regeneration updates the burgeoning field of regeneration in the Central Nervous System (CNS) from molecular, systems, and disease-based perspective. While the book covers numerous areas in detail, special emphasis is given to discussions of movement disorders such as Parkinson’s disease, Alzheimer’s disease, and spinal cord injury. Incorporates information gained from cutting-edge photomicroscopy techniques Includes current information on clinical trials Presents chapters on stem cells and other novel treatments for diseases of the CNS

Author :
Publisher : ScholarlyEditions
Page : 176 pages
File Size : 48,70 MB
Release : 2012-01-09
Category : Medical
ISBN : 1464926352

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Nerve Growth Factors: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Nerve Growth Factors. The editors have built Nerve Growth Factors: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Nerve Growth Factors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Nerve Growth Factors: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Lawrence Kruger
Publisher : CRC Press
Page : 458 pages
File Size : 43,39 MB
Release : 2009-11-24
Category : Health & Fitness
ISBN : 1439812101

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One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practical

Author : Dr.Hakim Saboowala
Publisher : Dr.Hakim Saboowala
Page : 64 pages
File Size : 32,18 MB
Release : 2022-01-06
Category : Medical
ISBN :

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Exploring the Clinical Implications of Brain-derived Neurotrophic Factor (BDNF). Brain-derived neurotrophic factor (BDNF) is one of the neurotrophic factors that support: · Differentiation, · Maturation, and · Survival of Neurons in the Nervous System and shows a Neuroprotective effect under adverse conditions, such as: · Glutamatergic stimulation, · Cerebral ischemia, · Hypoglycemia, and · Neurotoxicity. Brain-derived neurotrophic factor (BDNF) plays an important role in neuronal survival and growth, serves as a neurotransmitter modulator, and participates in neuronal plasticity, which is essential for learning and memory. BDNF and insulin-like growth factor-1 have similar downstream signalling mechanisms incorporating both p-CAMK and MAPK that increase the expression of pro-survival genes. Brain-derived neurotrophic factor regulates glucose and energy metabolism and prevents exhaustion of β cells. Decreased levels of BDNF are associated with neurodegenerative diseases with neuronal loss. Thus, an attempt has been made in this E-Booklet to describe everything about BDNF elaborately along with several relevant ILLUSRATIONS for better understanding! …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London)

Author : Richard Kostrzewa
Publisher : Springer Science & Business Media
Page : 410 pages
File Size : 14,1 MB
Release : 1997-10-30
Category : Medical
ISBN : 1592594778

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Expert researchers critically review and evaluate the most common and important neurotoxins used today in neuroscience research. Each informative chapter thoroughly describes the significant mechanisms of action of a neurotoxin, as well as fully discussing the limits on their use and their clinical applicability. Several clinically oriented chapters are significant for neurologists treating Parkinsonism, for psychiatrists treating drug abuse and neurodegenerative disorders, and for primary care physicians treating patients with appetite suppressants. Highly Selective Neurotoxins provides all the basic knowledge needed to obtain a predictable experimental outcome with these neurotoxins.

Author : John R. Wingard
Publisher : Springer Science & Business Media
Page : 424 pages
File Size : 41,91 MB
Release : 2012-12-06
Category : Medical
ISBN : 1461550130

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The hematopoietic system plays roles that are crucial for survival of the host: delivery of oxygen to tissues, arrest of accidental blood leaking from blood vessels, and fending off of invading microbes by humoral, cell-mediated, and phagocytic immunity. The activity of the hematopoietic system is staggering: daily, a normal adult produces approximately 2.5 billion erythrocytes, 2.5 billion platelets, and 1 billion granulocytes per kilogram of body weight. This production is adjusted in a timely fashion to changes in actual needs and can vary from nearly none to many times the normal rate depending on needs which vary from day to day, or even minute to minute. In response to a variety of stimuli, the cellular components of the blood are promptly increased or decreased in production to maintain appropriate numbers to optimally protect the host from hypoxia, infection, and hemorrhage. How does this all happen and happen without over or under responding? There has been extraordinary growth in our understanding ofhematopoiesis over the last two decades. Occupying center stage is the pluripotent stern cell and its progeny. Hematopoietic stern cells have been characterized by their capacity for self renewal and their ability to proliferate and differentiate along multiple lineages. Few in number, the stern cell gives rise to all circulating neutrophils, erythrocytes, lymphoid cells, and platelets. In hematopoietic transplantation, the stern cell is capable of restoring long-term hematopoiesis in a lethally irradiated host.

Author : Napoleone Ferrara
Publisher : CRC Press
Page : 304 pages
File Size : 47,31 MB
Release : 2006-08-15
Category : Medical
ISBN : 1420004379

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Why a new book on angiogenesis and why now? For the first time concepts proposed over 30 years ago have found clinical validation. In the last two years the first antiangiogenic agents have been approved by the FDA for the treatment of cancer and age-related macular degeneration. Not surprisingly, this clinical success has raised a new set of basic