[PDF] Cell And Molecular Biology Of The Cytoskeleton eBook

Author : Thomas Dean Pollard
Publisher :
Page : 0 pages
File Size : 27,5 MB
Release : 2017
Category : Cell membranes
ISBN : 9781621820161

GET BOOK

The cytoskeleton is the intracellular filament system that controls the morphology of a cell, allows it to move, and provides trafficking routes for intracellular transport. It comprises three major filament systems-actin, microtubules, and intermediate filaments-along with a host of adaptors, regulators, molecular motors, and additional structural proteins. This textbook presents a comprehensive and up-to-date view of the cytoskeleton, cataloguing its many different components and explaining how they are functionally integrated in different cellular processes. It starts by laying out the basic molecular hardware, before describing in detail how these components are assembled in cells and linked to neighboring cells and the extracellular matrix to maintain tissue architecture. It then surveys the roles of the cytoskeleton in processes such as intracellular transport, cell motility, signal transduction, and cell division. The book is thus essential reading for students learning about intracellular structure. It also represents a vital reference for all cell and developmental biologists working in this field.

Author : Manfred Schliwa
Publisher : Springer Science & Business Media
Page : 336 pages
File Size : 20,84 MB
Release : 2012-12-06
Category : Science
ISBN : 3709176670

GET BOOK

The term cytoskeleton has become firmly established in today's scientific vocabulary. Indeed, it is difficult to believe that only ten years ago, it was virtually non-existent. Since then, the modern field of research on the structural organization of the cytoplasm has turned into one of the most productive and rapidly expanding research areas in Cell Biology today. Considerable progress has been made towards the identification of the various structural components of the cytoskeleton and their interactions with one another and with membranes. The first attempts to understand, in molecular terms, complex cellular processes such as shape changes, locomotion, division, and organelle movements have been made. And it is now apparent that the cytoskeleton has impact on other biological processes such as the control of gene expression, protein synthesis, cell cycle regulation, and development. This monograph outlines the basic properties of the major components of the polymeric filament networks and their interactions and associations. Wherever possible, emphasis is placed on more recent references. Any attempt to cover a research field this complex in an introductory mono graph is, by necessity, fragmentary, and oversights or omissions are inevitable. I wish to apologize in advance to all those colleagues who feel that their work is not adequately represented.

Author : Linda A. Amos
Publisher :
Page : 253 pages
File Size : 35,73 MB
Release : 1991
Category : Cytoskeletal proteins
ISBN : 9780333495957

GET BOOK

Research into the cytoskeleton has produced a long list of polypeptides, whose properties "in vitro" have been studied in varying degrees of detail. The aim of this book is to introduce students to this array of proteins.

Author : R.D. Goldman
Publisher : Springer Science & Business Media
Page : 483 pages
File Size : 34,92 MB
Release : 2013-06-29
Category : Science
ISBN : 1475796048

GET BOOK

Research activity on intermediate filaments (IF) has increased dramatically over the past decade. For the most part, this surge of interest is due to their identification as ubiquitous constituents of the cytoskeleton and karyoskeleton (nuclear matrix) of eukaryotic cells and the fact that we know very little regarding their functions. In sharp contrast to the other major cytoskeletal systems, microfilaments and microtubules, IF exhibit a high degree of heterogeneity with regard to their protein subunit composition. Indeed, one can only marvel at the number of different IF polypeptides, their associated proteins (IFAP) and, consequently, the number of genes involved in encoding the multiple constituents of the various IF networks found in different cell types. The chapters in this book demonstrate how various experimental approaches involv ing cellular, molecular, biochemical, and immunological methods have been utilized to generate information regarding the structure and function of IF. To this end, we have gathered together chapters from experts in the major fields of IF research. In each chapter, the authors have combined reviews of the available scientific literature with their own ideas on current and future directions for IF research. The chapters have been divided into five major sections which are concerned with the subcellular organization of IF, the molecular structure of IF, the differential expression of IF genes, descriptions of associ ated proteins involved in the intracellular organization of IF, and finally an analysis of the changes seen in IF in pathological conditions.

Author : Edward Bittar
Publisher : Elsevier Science
Page : 270 pages
File Size : 46,47 MB
Release : 1992
Category : Science
ISBN : 9781559382090

GET BOOK

The fourth volume of the Advances in Molecular and Cell Biology series. Cell biology is a rapidly-developing discipline, bringing together many separate biological sciences. The interrelations of cell structure and function at molecular and subcellular levels are the central theme of the series.

Author :
Publisher : Elsevier
Page : 364 pages
File Size : 10,83 MB
Release : 2011-09-02
Category : Science
ISBN : 0080469396

GET BOOK

This volume provides an overview of the cytoskeleton particularly on the fundamental role the cytoskeleton plays in the regulation of cell structure and function. This book represents new trends in cytoskeletal research that go beyond the traditional approach of identifying new proteins in the cytoskeleton, but actually define how these proteins interact with signaling pathways. While the major emphasis in this volume remains on the microfilament structure, some discussion has been included in this volume to illustrate the similarities and differences between the three cytoskeletal elements namely the actin microfilament, the intermediate filaments and the microtubules.

Author : Ron Milo
Publisher : Garland Science
Page : 400 pages
File Size : 47,60 MB
Release : 2015-12-07
Category : Science
ISBN : 1317230698

GET BOOK

A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid