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Author : Dennis J. McKenna
Publisher : Psychology Press
Page : 1172 pages
File Size : 11,81 MB
Release : 2002
Category : Dietary supplements
ISBN : 9780789012661
Donated by The Australian Commercial Herb Growers Association.
Author : Iris F. F. Benzie
Publisher : CRC Press
Page : 500 pages
File Size : 38,76 MB
Release : 2011-03-28
Category : Health & Fitness
ISBN : 1439807167
The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef
Author : Bikarma Singh
Publisher : Springer Nature
Page : 481 pages
File Size : 39,92 MB
Release : 2020-10-05
Category : Medical
ISBN : 9811559171
Active botanical ingredients are a prime requirement for herbal formulations and discovering a drug is all about integration of science disciplines. In recent decades there has been a growing interest in treating wounds and diseases using traditional remedies based on local herbs, combined with chemical advances. Although this has led to the development of new bioactive ingredients from plants, there has been little success in terms of clinical trials and post-marketing studies to comply with FDA guidelines. Plants have been used as a source of medicine throughout history and continue to serve as the basis for many pharmaceuticals used today. However, despite the modern pharmaceutical industry being founded on botanical medicine, synthetic approaches to drug discovery have now become standard. Science-driven translational discovery and botanical development has created a new reality, leading to enormous changes in strategies, technologies and the disciplines involved, which have been embraced by the pharmaceutical and biotech industries. This book gathers scientific expertise and traditional knowledge to promote the discovery and development of new formulations and drugs based on active ingredients and to provide guidance on taking these to clinical trials. It discusses major topics, such as how the phytochemical composition of many plants has changed over time due to factors like cultivation, which can have both positive and negative effects on the levels of bioactive compounds. It also explores the importance of plants as a valuable source of therapeutic compounds as a result of their vast biosynthetic capacity, and classifies them according to their intended use, safety and regulatory status. Further, the book offers insights into the regulatory aspects of botanical products, which is an important issue when considering standardization and quality assessment, and also examines the commercial aspects of plant-derived medications and their proven role in the treatment of chronic diseases such as heart disease, high blood pressure, pain, asthma, and other associated conditions. Given its scope, this book is a valuable tool for botanists, natural product chemists, pharmacologists and microbiologists involved in the study of phytochemicals for drug discovery.
Author : Jayant N. Lokhande
Publisher : CRC Press
Page : 221 pages
File Size : 23,7 MB
Release : 2018-12-03
Category : Health & Fitness
ISBN : 1315352281
Botanicals, which have been part of human food and medicine for thousands of years, are perceived as being safer than synthetic pharmaceuticals. The global botanical drug market was expected to reach $26.6 billion by 2017. In terms of FDA regulations, botanical drugs are no different from non-botanical products, having to meet the safety and effectiveness standards of a new drug in accordance. This book comprises a complete start-to-end process from drug-idea conception, to drug development process.
Author : Jayant N. Lokhande
Publisher : CRC Press
Page : 295 pages
File Size : 15,53 MB
Release : 2018-11-21
Category : Health & Fitness
ISBN : 1498740065
Botanicals, which have been part of human food and medicine for thousands of years, are perceived as being safer than synthetic pharmaceuticals. The global botanical drug market was expected to reach $26.6 billion by 2017. In terms of FDA regulations, botanical drugs are no different from non-botanical products, having to meet the safety and effectiveness standards of a new drug in accordance. This book comprises a complete start-to-end process from drug-idea conception, to drug development process. Key Features: Provides a complete compendium for botanical drug products Describes what BDP is and how it differs from Pharma, Biopharma, and Nutraceuticals Compiles all critical regulatory steps in a variety of countries Discusses clinical trial management for BDP development and how it differs from conventional chemical-based drugs and biopharmaceutics
Author : Dominic Milton Trott
Publisher :
Page : pages
File Size : 22,72 MB
Release : 2017-10-03
Category :
ISBN : 9780995593619
This is the full colour coffee table edition of The Honest Drug Book, with dimensions of 8.5" x 11" (21.59 x 27.94 cm). Produced to do justice to the hundreds of photographs, it also allows a more leisurely perusal of the contents. The Honest Drug Book presents the hidden truth about a topic which touches the lives of almost everyone. It cuts through the blustering rhetoric of the war on drugs, and documents the facts about the subject in general, and about the individual drugs specifically. This is a journey through 140 psychoactives, both chemical and botanical, each of which was personally tested and used by the author. For every drug, it lists the fundamental and sometimes life-critical information, including the anticipated onset, the common threshold doses, and the expected period of efficacy. It also describes the subjective experience: what the drug was actually like at each stage of the duration. These 'trip reports' are vital, as they help to identify pitfalls and specific risks for each substance. Often, this is achieved in a humorous and anecdotal manner, which is occasionally accentuated by the fact that the author had to travel the world to undertake the experiments lawfully. In addition to these often rich and lengthy reports, the book is crammed with data and general information, inclusive of legal briefings, relative harm tables, addiction and overdose advice, detailed reference material, and even a drug dictionary. Of critical importance is the first section, as it introduces the basics of harm reduction, in the form of a 10 step procedure to help mitigate risk. The same section explains core safety issues, such as how to test and identify a drug, and how to properly establish a dose. The book itself is lavishly illustrated with hundreds of photographs, including of the drugs themselves. The images in the botanical section also encompass some of the indigenous settings encountered on the journey. The full gamut of psychoactive chemicals and botanicals is covered. The well known include: LSD, heroin, cannabis, mephedrone, kratom, cocaine, 2C-B, DMT, yopo, methamphetamine, salvia divinorum, ketamine, ayahuasca and MDMA. The lesser known include: betel nut, 4-ho-met, changa, TPA, 4F-MPH, ephenidine, ololiuqui, cebil seeds, mapacho, MNA, celastrus paniculatus, yohimbe, and MEAI. The scope also extends beyond the most common categories of hallucinogens, stimulants, depressants, cannabinoids and opioids. Included, for example, are nootropics (smart drugs) and oneirogenics (lucid and vivid dream herbs). Another dimension, which is covered largely in the final section, is that of politics and the war on drugs. This is confronted head-on, with a statement of intent which is crystal clear: "People are dying because of ignorance. They are dying because unremitting propaganda is denying them essential safety information. They are dying because legislators and the media are censoring the science, and are ruthlessly pushing an ideological agenda instead. They are dying because the first casualty of war is truth, and the war on drugs is no different. This book is a step to counter this harrowing and destructive situation." Emphasised and underpinned throughout is personal safety and risk mitigation. This is the first and last message, and guides the entire narrative. This is a book that won't only fascinate and inform: it will save lives.
Author : Roy Upton
Publisher : CRC Press
Page : 800 pages
File Size : 29,24 MB
Release : 2016-04-19
Category : Health & Fitness
ISBN : 1420073281
Winner of the James A. Duke Award for Excellence in Botanical Literature Award from the American Botanical CouncilCompiled by the American Herbal Pharmacopoeia, this volume addresses the lack of authoritative microscopic descriptions of those medicinal plant species currently in trade. It includes an atlas providing detailed text and graphic descri
Author : Antoine Al-Achi
Publisher : Bloomsbury Publishing USA
Page : 208 pages
File Size : 24,19 MB
Release : 2008-08-30
Category : Health & Fitness
ISBN : 0313350108
For those who want to make educated decisions about whether, and when, to use natural products, this text explains the most current scientific evidence of the roles that plants can play in our health: how they can prevent, modify, or treat disease. Since antiquity, humans have used botanicals to treat various conditions affecting their organ systems, and this book is built around explaining which plants may be used for major ailments affecting the various systems. The increasing availability of botanicals on the market, intended to be used as dietary supplements for health, has been fueled by the public's demand for a more natural approach to healthcare. Unfortunately, much of the information fed to the public on alternatives is based on anecdotal evidence (case stories), the advice of friends, or media features that often do not stand up to standards for scientific evidence. In this book Al-Achi explains current research and science that exists - or remains lacking - for the various botanicals as healthcare products. He also details the potential misuse and the dangers of some herbal formulas. Photographs of 62 medicinal plants are included. For those who want to make educated decisions whether, and when, to use natural products, this text explains the most current scientific evidence of the roles that plants can play in our health: how they can prevent, modify, or treat disease. Since antiquity, humans have used botanicals to treat various conditions affecting their organ systems, and this book is built around explaining which plants may be used for major ailments affecting the various systems. The increasing availability of botanicals on the market, intended to be used as dietary supplements for health, has been fueled by the public's demand for a more natural approach to healthcare. Unfortunately, much of the information fed to the public on alternatives is based on anecdotal evidence (case studies), the advice of friends, or media features that often do not stand up to standards for scientific evidence. In this book, Al-Achi explains current research and science that exists - or remains lacking - for the various botanicals as healthcare products. He also details the potential misuse and the dangers of some herbal formulas. Photographs of 62 medicinal plants are included. Because of its evidentiary approach, this book may serve also as a text for introductory college courses in the field of botanical medicine, or as a supplemental general text for an alternative and complementary medicine course. The history leading to the use of botanicals in healthcare is described, as are botanicals used in the treatment of cancer, cardiovascular disease, endocrine system disorders such as diabetes, gastrointestinal problems, men's and women's specific disorders, infections, chronic pain, psychological disorders such as anxiety and depression, and other health issues.
Author : Susan G. Wynn
Publisher : Elsevier Health Sciences
Page : 736 pages
File Size : 50,30 MB
Release : 2006-11-29
Category : Medical
ISBN : 0323029981
This full-color reference offers practical, evidence-based guidance on using more than 120 medicinal plants, including how to formulate herbal remedies to treat common disease conditions. A body-systems based review explores herbal medicine in context, offering information on toxicology, drug interactions, quality control, and other key topics. More than 120 herbal monographs provide quick access to information on the historical use of the herb in humans and animals, supporting studies, and dosing information. Includes special dosing, pharmacokinetics, and regulatory considerations when using herbs for horses and farm animals. Expanded pharmacology and toxicology chapters provide thorough information on the chemical basis of herbal medicine. Explores the evolutionary relationship between plants and mammals, which is the basis for understanding the unique physiologic effects of herbs. Includes a body systems review of herbal remedies for common disease conditions in both large and small animals. Discusses special considerations for the scientific research of herbs, including complex and individualized interventions that may require special design and nontraditional outcome goals.
Author : Ben-Erik van Wyk
Publisher : University of Chicago Press
Page : 305 pages
File Size : 40,77 MB
Release : 2015-06-22
Category : Science
ISBN : 022620507X
Plants have been used to treat disease throughout human history. On a clay slab that dates back approximately five thousand years, the Sumerians recorded medicinal recipes that made use of hundreds of plants, including poppy, henbane, and mandrake. During the Middle Ages, monks commonly grew and prescribed plants such as sage, anise, and mint in their monasteries. And as the market for herbal remedies and natural medicine grows, we continue to search the globe for plants and plant compounds to combat our various ailments. In Phytomedicines, Herbal Drugs, and Poisons, Ben-Erik van Wyk offers a richly illustrated, scientific guide to medicinal and poisonous plants, including those used for their mind-altering effects. Van Wyk covers approximately 350 species—from Aloe vera and Ephedra sinica to Cannabis sativa and Coffea arabica—detailing their botanical, geographical, pharmacological, and toxicological data as well as the chemical structures of the active compounds in each. Readers learn, for example, that Acacia senegal, or gum acacia, is used primarily in Sudan and Ethiopia as a topical ointment to protect the skin and mucosa from bacterial and fungal infections, and that Aconitum napellus, more commonly known as aconite, is used in cough syrups but can be psychedelic when smoked or absorbed through the skin. With 350 full-color photographs featuring the plants and some of their derivative products, Phytomedicines, Herbal Drugs, and Poisons will be an invaluable reference not only for those in the health care field but also for those growing their own medicinal herb gardens, as well as anyone who needs a quick answer to whether a plant is a panacea or a poison.