[PDF] Blood Vessel Wall And Thrombosis eBook

Author : Taylor & Francis Group
Publisher : Routledge
Page : 332 pages
File Size : 49,81 MB
Release : 2020-12
Category :
ISBN : 9780367262075

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First published in 1988, this 2 volume set presents the latest, authoritative information on the regulatory role of the blood vessel wall on the process of hemostasis in health and disease.

Author : Michel Félétou
Publisher : Morgan & Claypool Publishers
Page : 309 pages
File Size : 22,72 MB
Release : 2011
Category : Science
ISBN : 1615041230

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The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References

Author : Rolando E. Rumbaut
Publisher : Biota Publishing
Page : 77 pages
File Size : 23,30 MB
Release : 2010-02-01
Category : Medical
ISBN : 1615040404

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Platelets are essential mediators of the physiologic process of hemostasis and pathologic thrombosis. While platelets do not interact with vascular walls under normal conditions, vascular injury or inflammation result in a coordinated series of events including platelet adhesion, aggregation, and promotion of coagulation. In this review, we describe the primary mechanisms involved in these responses in various vascular beds of both macro- and microvessels, and outline key unresolved aspects of these important interactions.

Author : Robert Fitridge
Publisher : University of Adelaide Press
Page : 589 pages
File Size : 22,58 MB
Release : 2011
Category : Medical
ISBN : 1922064009

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New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.