[PDF] Bipolar Disorder Vulnerability eBook

Author : Jair Soares
Publisher : Academic Press
Page : 0 pages
File Size : 28,22 MB
Release : 2018-06-12
Category : Medical
ISBN : 9780128123478

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Bipolar Disorder Vulnerability: Perspectives from Pediatric and High-Risk Populations synthesizes our current understanding of high-risk and pediatric populations to aid readers in identifying markers of vulnerability for the development of bipolar disorder, with an ultimate goal of the development of drug targets and other therapies for early diagnosis and treatment. The book provides readers with an understanding of biological and environmental factors influencing disease manifestation that will aid them in defining discrete clinical stages and, importantly, establish an empirical basis for the application of novel therapeutics in a phase of illness during which specific treatments could more effectively alter disease course. Whereas most of the literature available on the pathophysiological mechanisms of bipolar disorder focuses on chronically ill adult individuals, this represents the only book that specifically examines pediatric and high-risk populations. An estimated 30 to 60 percent of adult bipolar disorder patients have their disease onset during childhood, with early-onset cases representing a particularly severe and genetically loaded form of the illness.

Author : Jair Soares
Publisher : Academic Press
Page : 290 pages
File Size : 23,59 MB
Release : 2018-06-09
Category : Medical
ISBN : 0128125608

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Bipolar Disorder Vulnerability: Perspectives from Pediatric and High-Risk Populations synthesizes our current understanding of high-risk and pediatric populations to aid readers in identifying markers of vulnerability for the development of bipolar disorder, with an ultimate goal of the development of drug targets and other therapies for early diagnosis and treatment. The book provides readers with an understanding of biological and environmental factors influencing disease manifestation that will aid them in defining discrete clinical stages and, importantly, establish an empirical basis for the application of novel therapeutics in a phase of illness during which specific treatments could more effectively alter disease course. Whereas most of the literature available on the pathophysiological mechanisms of bipolar disorder focuses on chronically ill adult individuals, this represents the only book that specifically examines pediatric and high-risk populations. An estimated 30 to 60 percent of adult bipolar disorder patients have their disease onset during childhood, with early-onset cases representing a particularly severe and genetically loaded form of the illness. Highlights diverse translational methodologies, including functional and structural neuroimaging, neuropsychological testing and integrated genomics Examines molecular trajectories in youth with bipolar disorder and unaffected youth at high risk for developing bipolar disorder Explores the interaction between genomic and environmental influences that shape behavior

Author : T. A. Greeenwood
Publisher :
Page : pages
File Size : 18,14 MB
Release : 2020
Category :
ISBN :

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Bipolar disorder is a lifelong mood disorder characterized by extreme mood swings between mania and depression. Despite fitness costs associated with increased mortality and significant impairment, bipolar disorder has persisted in the population with a high heritability and a stable prevalence. Creativity and other positive traits have repeatedly been associated with the bipolar spectrum, particularly among unaffected first-degree relatives and those with milder expressions of bipolar traits. This suggests a model in which large doses of risk variants cause illness, but mild to moderate doses confer advantages, which serve to maintain bipolar disorder in the population. Bipolar disorder may thus be better conceptualized as a dimensional trait existing at the extreme of normal population variation in positive temperament, personality, and cognitive traits, aspects of which may reflect a shared vulnerability with creativity. Investigations of this shared vulnerability may provide insight into the genetic mechanisms underlying illness and suggest novel treatments.

Author : Lauren B. Alloy
Publisher : Routledge
Page : 462 pages
File Size : 45,77 MB
Release : 2006-04-21
Category : Psychology
ISBN : 1135648778

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Emotional disorders such as anxiety, depression, and dysfunctional patterns of eating are clearly among the most devastating and prevalent confronting practitioners, and they have received much attention from researchers--in personality, social, cognitive, and developmental psychology, as well as in clinical psychology and psychiatry. A major recent focus has been cognitive vulnerability, which seems to set the stage for recurrences of symptoms and episodes. In the last five years there has been a rapid proliferation of studies. In this book, leading experts present the first broad synthesis of what we have now learned about the nature, of cognitive factors that seem to play a crucial role in creating and maintaining vulnerability across the spectrum of emotional disorders. An introductory chapter considers theory and research design and methodology and constructs a general conceptual framework for understanding and studying the relationships between developmental and cognitive variables and later risk, and the difference between distal cognitive antecedents of disorders (e.g. depressive inferential styles, dysfunctional attitudes) and proximal ones (e.g. schema activation or inferences). Subsequent chapters are organized into three sections, on mood, anxiety, and eating disorders. Each section ends with an integrative overview chapter that offers both incisive commentary and insightful suggestions for further systematic research. A rich resource for all those professionally concerned with these problems, Cognitive Vulnerability to Emotional Disorders advances both clinical science and clinical practice.

Author : Rick E. Ingram
Publisher : Guilford Press
Page : 273 pages
File Size : 48,18 MB
Release : 2011-07-07
Category : Psychology
ISBN : 160918257X

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Providing a cutting-edge examination of the mechanisms underlying depression, this volume integrates important areas of research that have largely remained separate. The authors explore both the cognitive and neurological processes that make some people more vulnerable than others to developing depression and experiencing recurrent episodes. They also probe how these processes interact—how negative life experiences, maladaptive belief systems, and patterns of thinking may actually affect neural circuitry, and vice versa. Explaining sophisticated theory and research in an accessible style, the book highlights the implications for improving clinical practices and patient outcomes.

Author : Robert L. Leahy
Publisher : Guilford Publications
Page : 433 pages
File Size : 16,80 MB
Release : 2018-01-31
Category : Psychology
ISBN : 1462533388

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From leading experts in cognitive-behavioral therapy (CBT)--including CBT originator Aaron T. Beck and many who have worked closely with him--this book provides an overview of where the field is today and presents cutting-edge research and clinical applications. Contributors explain how Beck's cognitive model has been refined and tested over the last 45 years and describe innovative CBT approaches that integrate mindfulness, imagery, emotion-focused interventions, and other strategies. Chapters on specific clinical problems cover the conceptualization and treatment of depression, anxiety disorders, posttraumatic stress disorder, obsessive?compulsive disorder, insomnia, suicidality, substance abuse, couple and family problems, bipolar disorder, psychosis, and personality disorders. ÿ