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The book covers conjugation of biopolymers with synthetic polymers, nanoparticles, metals, phytochemicals, food additives and biopolymers, such as polynucleotides, polypeptides and polysaccharides. It describes the latest research advances on biopolymers extracted from waste and their corresponding products.
The book covers conjugation of biopolymers with synthetic polymers, nanoparticles, metals, phytochemicals, food additives and biopolymers, such as polynucleotides, polypeptides and polysaccharides. It describes the latest research advances on biopolymers extracted from waste and their corresponding products.
Polypeptide-Polymer Conjugates, by Henning Menzel Chemical Strategies for the Synthesis of Protein-Polymer Conjugates, by Björn Jung and Patrick Theato Glycopolymer Conjugates, by Ahmed M. Eissa and Neil R. Cameron DNA-Polymer Conjugates: From Synthesis, Through Complex Formation and Self-assembly to Applications, by Dawid Kedracki, Ilyès Safir, Nidhi Gour, Kien Xuan Ngo and Corinne Vebert-Nardin Synthesis of Terpene-Based Polymers, by Junpeng Zhao and Helmut Schlaad
Polymer–Protein Conjugates: From Pegylation and Beyond helps researchers by offering a unique reference and guide into this fascinating area. Sections cover the challenges surrounding the homogeneity of conjugates, their purity and polymer toxicity on long-term use, and how to deal with the risk of immunogenicity. These discussions help researchers design new projects by taking into account the latest innovations for safe and site selective polymer conjugation to proteins. PEG has been the gold standard and likely will play this role for many years, but alternatives are coming into the market, some of which have already been launched. After five decades of improvements, the ideas in this book are entering into a new era of innovation because of the advances in genetic engineering, biochemistry and a better understanding of the results from clinical use of PEG conjugates in humans. Provides an overview on the state-of-the-art of protein polymer conjugation Presents both the pros and cons of polymer-protein conjugates from the point-of-view of their clinical outcomes Outlines advantages and potential risks of present technology based on PEG Offers new alternatives for PEG and new approaches for on site-selective protein modification Identifies future direction of research in this field
Polymer-Drug Conjugates: Linker Chemistry, Protocols and Applications discusses important concepts, fundamentals and prospective applications of ‘Linker Chemistry’ in a clear-and-concise manner. The book provides vital information on chemical entities binding with the drug-polymer complex for targeted drug delivery systems. It highlights roles and significance, different classes and synthetic protocols as well as mechanisms of chemical bond formation in drug-polymer conjugation in drug delivery, also offering insights into the mechanism of polymer interaction with linker and drug molecules by biodegradable chemical bonding. The protocol of binding with drug molecules is clearly explained and justified with case studies, helping researchers and advanced students in the pharmaceutical sciences understand fundamentals involved and related aspects in molecule designing for effective therapeutic benefits. Covers mechanism, protocol and therapeutic significance of Polymer-Drug Conjugates Outlines updated methods and techniques to enumerate conjugation with related case studies Includes comprehensive compilation of marketed and clinical trial drugs conjugated with polymers or linkers
Biopolymers: Synthesis, Properties, and Emerging Applications presents the state-of-the-art in biopolymers, bringing together detailed information on synthesis strategies, processing and cutting-edge applications. The book begins by introducing the synthesis, processing and structural and functional properties of smart biopolymers and bionanocomposites. Subsequent chapters focus on the synthesis and preparation of biopolymers with valuable properties or for specific advanced applications, including piezoelectric properties, shape memory properties, biodegradable polymer blends, synthesis and assembly of nanomaterials, synthesis of green biopolymers, and catalytic synthesis of bio-sourced polyesters and polycarbonate, as well as applications in active food packaging, water purification, biomedicine, 3D printing, and automotive. Throughout the book, there are analyses of different synthesis strategies and processing methods and their role and use in different fields of application, whilst the important challenges relating to scalable processing and shaping and micro and nano structuration are also discussed. The book also strives to balance the synthetic aspects of biopolymers with physical principles, highlighting biopolymer-based architectures including composite or hybrid conjugates, providing in-depth discussion of important examples of reaction mechanisms, and exploring potential applications of biopolymer and conjugates, ranging from physical to chemical and biological systems. Provides the reader with a broad and detailed overview of the latest advances in biopolymers, covering synthesis, processing, properties and applications Examines synthesis strategies and processing methods, focusing on green and sustainable catalytic synthesis approaches for biopolymer production Reviews smart applications of biopolymers, including active food packaging, photocatalytic, electric, electronic, piezoelectric, antimicrobial, environmental, and more
This first book to specifically focus on applications of conjugated polymers in the fields of biology and biomedicine covers materials science, physical principles, and nanotechnology. The editor and authors, all pioneers and experts with extensive research experience in the field, firstly introduce the synthesis and optical properties of various conjugated polymers, highlighting how to make organic soluble polymers compatible with the aqueous environment. This is followed by the application of these materials in optical sensing and imaging as well as the emerging applications in image-guided therapy and in the treatment of neurodegenerative diseases. The result is a consolidated overview for polymer chemists, materials scientists, biochemists, biotechnologists, and bioengineers.
Tailor-Made and Functionalized Biopolymer Systems: For Drug Delivery and Biomedical Applications covers the design and application of these functionalized and tailor-made biopolymers and biopolymer systems intended for drug delivery and biomedical applications. Various concepts, design protocols and biomedical applications of tailor-made biopolymer systems are covered, guiding the reader from theoretical knowledge to practical application. Authored by an array of experts from global institutions, this book offers an interdisciplinary approach to how tailor-made biopolymers lead to novel drug delivery and treatment solutions. This will be a useful reference to a broad audience, including biomedical engineers, materials scientists, pharmacologists and chemists. Provides a concise overview of tailor-made and functionalized biopolymer systems for biomedical applications Covers a range of modified biopolymers, biopolymeric composites and biopolymer-based systems in drug delivery, development of artificial organs, diagnostic applications, and more Describes characterization, synthesis and functionalization of biopolymers and biopolymers systems
This book is written to serve as textbook on biomaterials and biopolymers for faculty and students and thus contains a broad introduction and basic terms, followed by major developments over the years with some emphasis on recent developments and future prospects. It provide a comprehensive overview in biomaterials and biopolymers. All relevant aspects of modern biomaterials, including: synthesis and characterization, biocompatibility and host response, the implementation of novel manufacturing processes, and advanced medical and biotechnological applications. Each chapter provides an overview of a specific field, its importance, the chemistry of biomaterials and the relations between chemical structure and the applications. Each chapter ends with a future prospective/concepts and a friendly quiz/multiple answer questions with answers that serves as a resource to provide guided additional practice.