[PDF] Biology And Pathology Of Trophoblast eBook

Author : Ashley Moffett
Publisher : Cambridge University Press
Page : 246 pages
File Size : 50,52 MB
Release : 2011-08-18
Category : Medical
ISBN : 1139452541

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Originally published in 2006, this book provides an in-depth account of trophoblast: the tissue derived from the fertilised egg that nourishes and protects the developing fetus. The cells of the trophoblast have many unique qualities, and exhibit great variability across different species. It has a fascinating role in the development of the placenta and as a regulator during early growth of the embryo. These aspects are all fully covered as well as studies on why it is not rejected by the mother as 'foreign' tissue. Disorders of trophoblast during development also manifest themselves in several clinical conditions during pregnancy, including gestational trophoblastic disease and pre-eclampsia. From stem cells through to epigenetics, implantation and X-chromosome inactivation, there is a lot to be learned about trophoblast, this volume provides a detailed summary of knowledge regarding the subject.

Author : A. Gropp
Publisher : Springer Science & Business Media
Page : 317 pages
File Size : 40,57 MB
Release : 2012-12-06
Category : Medical
ISBN : 364266458X

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The early development of the mammalian embryo belongs to a period which, for the student, provides the particularly deep fascination connected with the processes of germination of the fIrst tender buds of life. Moreover, developmental biology encompasses a very large part of biology; if broadly dermed - almost all of it. The same is true for the fIeld of pathology if the manifold possibilities of disorders of the orderly arranged pathways of developmental processes are considered. Normal development in its earliest steps - and it would be diffI cult to see it otherwise - means the functioning of very intricate systems of complex inter dependent cycles controlled by structural, genetic, physiological and biochemical determi nants. However, disturbances interfering with them in their very different ways, can lead to fetal death, disorders of growth and differentiation, malformation and disease, sometimes as late as in the next generation or later. This is, indeed, the concern of the pathologist to whom and to whose interest in developmental pathology, this book is dedicated. The outlines of the present volume were conceived at a symposium on "Control of early em bryogenesis and factors responsible for failure of embryonic development" held May 1-4, 1974 in Travemtinde and sponsored by the Deutsche Forschungsgemeinschaft. Almost fIfty active participants attended this conference. At the time and in keeping with the purpose of the conference, publication of the proceedings was not envisaged.

Author : Kurt Benirschke
Publisher : Springer Science & Business Media
Page : 1069 pages
File Size : 15,55 MB
Release : 2006-11-17
Category : Medical
ISBN : 0387267425

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Pathology of the Human Placenta remains the authoritative text in the field and is respected and used by pathologists and obstetrician-gynecologists alike. This fifth edition reflects new advances in the field and includes 800 illustrations, 173 of them in color. The detailed index has been improved and the tables updated. Defined terms are highlighted in bold for easy identification, and further findings are discussed in small type throughout each chapter. Advances in genetics and molecular biology continue to make the study of the placenta one of vast diagnostic and legal importance.

Author : Kurt Benirschke
Publisher : Springer Science & Business Media
Page : 1068 pages
File Size : 40,1 MB
Release : 2012-06-16
Category : Medical
ISBN : 3642239412

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Pathology of the Human Placenta remains the most comprehensive and authoritative text in the field. It provides extensive information on the normal placenta, encompassing physiology, metabolism, and endocrinology, and covers the full range of placental diseases in great detail. Further chapters are devoted to abortions, molar pregnancies, multiple pregnancies, and legal considerations. This sixth edition of the book has been extensively revised and expanded to reflect the most recent progress in the field, and a brand new chapter has been added on artificial reproductive technology. Some 800 illustrations are included, many of them in color. The detailed index has been further improved and tables updated. Pathology of the Human Placenta will be of enormous value to pathologists and obstetrician-gynecologists alike.

Author : Pei Hui
Publisher : Springer Science & Business Media
Page : 211 pages
File Size : 21,76 MB
Release : 2011-12-15
Category : Medical
ISBN : 1617793949

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In this volume Dr Hui has brought together a comprehensive overview of gestational trophoblastic disease that includes all the currently recognized entities: complete and partial hydatidiform moles, placental site trophoblastic tumor, epithelioid trophoblastic tumor, gestational choriocarcinoma, persistent gestational trophoblastic neoplasia, placental site nodule and exaggerated placental site reaction. Each entity is reviewed in detail, with emphasis on genetic background, clinical presentation, pathologic findings and ancillary studies, differential diagnosis and clinicopathological correlations. Descriptions of the pathology are supported by numerous excellent photomicrographs. Recent advances in our understanding of the genetics of gestational trophoblastic diseases are stressed. Introductory chapters cover the developmental biology of the placenta and the genetic basis of gestational trophoblastic disease, and one chapter is devoted to the molecular diagnosis of gestational trophoblastic disease. This chapter includes a review of the use of short tandem repeat (STR) genotyping which is of particular value in the diagnosis of hydatidiform moles. The final chapter covers clinical aspects of gestational trophoblastic disease, including treatment. The text throughout is current and thoroughly referenced. This book will be of great value to pathologists, community gynecologists, gynecological pathologists and medical students.

Author : Antonio Giordano
Publisher : Springer Science & Business Media
Page : 226 pages
File Size : 18,32 MB
Release : 2007-10-05
Category : Medical
ISBN : 1597453463

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This book focuses on putting successful molecular strategies into practice for the treatment of gynecologic cancer. It approaches research into the pathology and treatment of gynecologic oncology from both clinical and experimental perspectives. New insights made possible by the introduction of advanced technologies into the field are presented. This new volume will be necessary reading for clinicians and experimental researchers alike.

Author : Pei Hui
Publisher : Humana Press
Page : 205 pages
File Size : 43,79 MB
Release : 2016-08-23
Category : Medical
ISBN : 9781493959242

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In this volume Dr Hui has brought together a comprehensive overview of gestational trophoblastic disease that includes all the currently recognized entities: complete and partial hydatidiform moles, placental site trophoblastic tumor, epithelioid trophoblastic tumor, gestational choriocarcinoma, persistent gestational trophoblastic neoplasia, placental site nodule and exaggerated placental site reaction. Each entity is reviewed in detail, with emphasis on genetic background, clinical presentation, pathologic findings and ancillary studies, differential diagnosis and clinicopathological correlations. Descriptions of the pathology are supported by numerous excellent photomicrographs. Recent advances in our understanding of the genetics of gestational trophoblastic diseases are stressed. Introductory chapters cover the developmental biology of the placenta and the genetic basis of gestational trophoblastic disease, and one chapter is devoted to the molecular diagnosis of gestational trophoblastic disease. This chapter includes a review of the use of short tandem repeat (STR) genotyping which is of particular value in the diagnosis of hydatidiform moles. The final chapter covers clinical aspects of gestational trophoblastic disease, including treatment. The text throughout is current and thoroughly referenced. This book will be of great value to pathologists, community gynecologists, gynecological pathologists and medical students.

Author : Y. W. Loke
Publisher : Cambridge University Press
Page : 332 pages
File Size : 23,21 MB
Release : 1995-11-30
Category : Medical
ISBN : 9780521441933

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This book explains and reviews some of the significant events involved in human implantation and the establishment of the placenta in the uterus. This critical phase in human reproduction has proved to be an elusive and challenging area of research, not least because of the immunological and genetic interactions between the mother and fetus. The volume focuses on the most recent advances in our understanding of the basic mechanisms involved, with a particular emphasis on cell biology and immunology. This lucid volume will benefit all those studying and undertaking research in reproductive biology and immunology, perinatal pathology, fetal medicine and obstetrics.

Author : Raymond W. Redline
Publisher : Cambridge University Press
Page : 367 pages
File Size : 30,68 MB
Release : 2018-08-23
Category : Medical
ISBN : 1316632539

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A guide to identifying disease processes in the placenta affecting pregnancy outcome, with current diagnostic criteria and clinical consequences.