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This fifth edition of the most accessible introduction to MRI principles and applications from renowned teachers in the field provides an understandable yet comprehensive update. Accessible introductory guide from renowned teachers in the field Provides a concise yet thorough introduction for MRI focusing on fundamental physics, pulse sequences, and clinical applications without presenting advanced math Takes a practical approach, including up-to-date protocols, and supports technical concepts with thorough explanations and illustrations Highlights sections that are directly relevant to radiology board exams Presents new information on the latest scan techniques and applications including 3 Tesla whole body scanners, safety issues, and the nephrotoxic effects of gadolinium-based contrast media
Today, under pressure from managed care companies as well as from patients who are demanding briefer and more focused treatments, therapists are creatively combining cognitive and psychodynamic approaches and obtaining unprecedented therapeutic results. In this volume, Robert Leahy describes Aaron Beck's seminal model of depression, anxiety, anger, and relationship conflict and shows how each of these problems is handled by the cognitive therapist in the context of an interactive therapeutic relationship. Leahy demonstrates how uncovering resistance to change and using the therapeutic relationship enhances recovery and promotes rapid change. With concrete examples he shows how to implement all of the basic cognitive techniques, including: —activity scheduling —graded task assignments —exposure hierarchies —response prevention —challenging underlying schemas —thought monitoring Drawing from cognitive and dynamic orientations and taking into account the complexity of countertransference and resistance, this book is for today's clinicians who, rather than being wedded to a specific approach, are committed to a quick and successful therapeutic outcome. A Jason Aronson Book
Written by experienced experts in molecular modeling, this books describes the basics to the extent that is necessary if one wants to be able to reliably judge the results from molecular modeling calculations. Its main objective is the description of the various pitfalls to be avoided. Without unnecessary overhead it leads the reader from simple calculations on small molecules to the modeling of proteins and other relevant biomolecules. A textbook for beginners as well as an invaluable reference for all those dealing with molecular modeling in their daily work!
To understand the world around us, as well as ourselves, we need to measure many things, many variables, many properties of the systems and processes we investigate. Hence, data collected in science, technology, and almost everywhere else are multivariate, a data table with multiple variables measured on multiple observations (cases, samples, items, process time points, experiments). This book describes a remarkably simple minimalistic and practical approach to the analysis of data tables (multivariate data). The approach is based on projection methods, which are PCA (principal components analysis), and PLS (projection to latent structures) and the book shows how this works in science and technology for a wide variety of applications. In particular, it is shown how the great information content in well collected multivariate data can be expressed in terms of simple but illuminating plots, facilitating the understanding and interpretation of the data. The projection approach applies to a variety of data-analytical objectives, i.e., (i) summarizing and visualizing a data set, (ii) multivariate classification and discriminant analysis, and (iii) finding quantitative relationships among the variables. This works with any shape of data table, with many or few variables (columns), many or few observations (rows), and complete or incomplete data tables (missing data). In particular, projections handle data matrices with more variables than observations very well, and the data can be noisy and highly collinear. Authors: The five authors are all connected to the Umetrics company (www.umetrics.com) which has developed and sold software for multivariate analysis since 1987, as well as supports customers with training and consultations. Umetrics' customers include most large and medium sized companies in the pharmaceutical, biopharm, chemical, and semiconductor sectors.
Author : Scott H. Faro Publisher : Springer Science & Business Media Page : 543 pages File Size : 40,66 MB Release : 2006-11-22 Category : Medical ISBN : 0387346651
Functional magnetic resonance imaging (fMRI) measures quick, tiny metabolic changes that take place in the brain, providing the most sensitive method currently available for identifying, investigating, and monitoring brain tumors, stroke, and chronic disorders of the nervous system like multiple sclerosis, and brain abnormalities related to dementia or seizures. This overview explores experimental research design, outlines challenges and limitations of fMRI, provides a detailed neuroanatomic atlas, and describes clinical applications of fMRI in cognitive, sensory, motor, and pharmacological cases, translating research into clinical application.
Nuclear magnetic resonance (NMR) spectroscopy is one of the most powerful and widely used techniques in chemical research for investigating structures and dynamics of molecules. Advanced methods can even be utilized for structure determinations of biopolymers, for example proteins or nucleic acids. NMR is also used in medicine for magnetic resonance imaging (MRI). The method is based on spectral lines of different atomic nuclei that are excited when a strong magnetic field and a radiofrequency transmitter are applied. The method is very sensitive to the features of molecular structure because also the neighboring atoms influence the signals from individual nuclei and this is important for determining the 3D-structure of molecules. This new edition of the popular classic has a clear style and a highly practical, mostly non-mathematical approach. Many examples are taken from organic and organometallic chemistry, making this book an invaluable guide to undergraduate and graduate students of organic chemistry, biochemistry, spectroscopy or physical chemistry, and to researchers using this well-established and extremely important technique. Problems and solutions are included.
The book is an introduction to modern probability theory written by one of the famous experts in this area. Readers will learn about the basic concepts of probability and its applications, preparing them for more advanced and specialized works.
Now in its updated Third Edition, MRI: The Basics is an easy-to-read, clinically relevant introduction to the physics behind MR imaging. The book features large-size, legible equations, state-of-the-art images, instructive diagrams, and questions and answers that are ideal for board review. The American Journal of Radiology praised the previous edition as "an excellent text for introducing the basic concepts to individuals interested in clinical MRI." This edition spans the gamut from basic physics to multi-use MR options to specific applications, and has dozens of new images. Coverage reflects the latest advances in MRI and includes completely new chapters on k-space, parallel imaging, cardiac MRI, and MR spectroscopy.
Pharmaceutics: Basic Principles and Application to Pharmacy Practice, Second Edition is a valuable textbook covering the role and application of pharmaceutics within pharmacy practice. This updated resource is geared toward meeting and incorporating the current curricular guidelines on pharmaceutics and laboratory skills mandated by the American Council for Pharmacy Education. It includes a number of student-friendly features, including chapter objectives and summaries, practical examples, case studies, numerous images and key-concept text boxes. Two new chapters are included, as well as a new end of chapter section covering "critical reflections and practice applications". Divided into three sections – Physical Principles and Properties of Pharmaceutics; Practical Aspects of Pharmaceutics; and Biological Applications of Pharmaceutics – this new edition covers all aspects of pharmaceutics and providing a single and compelling source for students. Facilitates an integrated and extensive coverage of the study of pharmaceutics due to the clear and engaging language used by the authors Includes chapter objectives and summaries to illustrate and reinforce key ideas Meets curricular guidelines for pharmaceutics and laboratory skills mandated by the Accreditation Council for Pharmacy Education (ACPE) Includes new practice questions, answers, and case studies for experiential learning
PACS BASIC PRINCIPLES AND APPLICATIONS H. K. Huang, D.Sc. Picture archiving and communications systems (PACS) are the foundation of digital radiology and are increasingly being implemented to streamline health-care operations, facilitate teleradiology, and improve patient care. PACS: Basic Principles and Applications integrates a comprehensive introduction to the imaging modalities and technical fundamentals of "filmless radiology" with clear guidelines for designing and implementing a PACS system. Written by a leading expert and featuring numerous illustrations, line drawings, and schematic diagrams, this practical, user-friendly resource includes individual chapters on such topics as: * Digital radiologic image fundamentals * Industry standards, with an emphasis on HL7 and DICOM * Image compression * Image acquisition gateways * Communications and networking * System design, installation, and evaluation * Clinical applications and pitfalls * Future development of PACS PACS: Basic Principles and Applications is an essential reference and invaluable sourcebook for radiologists and radiology residents and technologists, as well as for imaging facility planners and support staff.