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Microbial Metabolomics

Author : David J. Beale
Publisher : Springer
Page : 324 pages
File Size : 18,35 MB
Release : 2016-12-05
Category : Science
ISBN : 3319463268

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This book brings together contributions from global experts who have helped to facilitate the exciting and rapid advances that are taking place in microbial metabolomics. The main application of this field is in clinical and veterinary microbiology, but there is a great potential to apply metabolomics to help to better understand complex biological systems that are dominated by multiple-species microbial populations exposed to changing growth and nutritional conditions. In particular, environmental (e.g., water, soil), food (e.g., microbial spoilage, food pathogens), and agricultural and industrial applications are seen as developing areas for microbial metabolomics. As such, the book includes contributions with clinical, environmental, and industrial perspectives.

Metabolism of Bacterial Infection

Author : Vijay Soni
Publisher : Springer
Page : 0 pages
File Size : 35,17 MB
Release : 2024-02-17
Category : Science
ISBN : 9783031468940

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This machine-generated literature overview provides a comprehensive and up-to-date summary of research on the role of bacterial metabolism in the pathogenesis of bacterial infections. It examines various aspects of bacterial metabolism, including metabolic pathways, nutrient acquisition activities, metabolic adaptation, virulence factors, antibiotic resistance, omics approaches, metabolic engineering, and therapeutic approaches. It is intended for students, researchers, and practitioners in the fields of microbiology, infectious disease, and biomedicine. The auto-summaries have been generated by a recursive clustering algorithm via the Dimensions Auto-summarizer by Digital Science handled by Subject Matter Experts and the external editor. The editor of this book selected which SN content should be auto-summarized and decided its order of appearance. Please be aware that the auto-summaries consist of original sentences, but are not representative of its original paper, since we do not show the full length of the publication. Please note that only published SN content is represented here, and that machine-generated books are still at an experimental stage.

Bacterial Biofilms

Author : Tony Romeo
Publisher : Springer Science & Business Media
Page : 302 pages
File Size : 13,6 MB
Release : 2008-02-26
Category : Medical
ISBN : 3540754180

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Throughout the biological world, bacteria thrive predominantly in surface-attached, matrix-enclosed, multicellular communities or biofilms, as opposed to isolated planktonic cells. This choice of lifestyle is not trivial, as it involves major shifts in the use of genetic information and cellular energy, and has profound consequences for bacterial physiology and survival. Growth within a biofilm can thwart immune function and antibiotic therapy and thereby complicate the treatment of infectious diseases, especially chronic and foreign device-associated infections. Modern studies of many important biofilms have advanced well beyond the descriptive stage, and have begun to provide molecular details of the structural, biochemical, and genetic processes that drive biofilm formation and its dispersion. There is much diversity in the details of biofilm development among various species, but there are also commonalities. In most species, environmental and nutritional conditions greatly influence biofilm development. Similar kinds of adhesive molecules often promote biofilm formation in diverse species. Signaling and regulatory processes that drive biofilm development are often conserved, especially among related bacteria. Knowledge of such processes holds great promise for efforts to control biofilm growth and combat biofilm-associated infections. This volume focuses on the biology of biofilms that affect human disease, although it is by no means comprehensive. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental, and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth.

Multivariate Observations

Author : George A. F. Seber
Publisher : John Wiley & Sons
Page : 718 pages
File Size : 25,10 MB
Release : 2009-09-25
Category : Mathematics
ISBN : 0470317310

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WILEY-INTERSCIENCE PAPERBACK SERIES The Wiley-Interscience Paperback Series consists of selected books that have been made more accessible to consumers in an effort to increase global appeal and general circulation. With these new unabridged softcover volumes, Wiley hopes to extend the lives of these works by making them available to future generations of statisticians, mathematicians, and scientists. "In recent years many monographs have been published on specialized aspects of multivariate data-analysis–on cluster analysis, multidimensional scaling, correspondence analysis, developments of discriminant analysis, graphical methods, classification, and so on. This book is an attempt to review these newer methods together with the classical theory. . . . This one merits two cheers." –J. C. Gower, Department of Statistics Rothamsted Experimental Station, Harpenden, U.K. Review in Biometrics, June 1987 Multivariate Observations is a comprehensive sourcebook that treats data-oriented techniques as well as classical methods. Emphasis is on principles rather than mathematical detail, and coverage ranges from the practical problems of graphically representing high-dimensional data to the theoretical problems relating to matrices of random variables. Each chapter serves as a self-contained survey of a specific topic. The book includes many numerical examples and over 1,100 references.

Metabolomics in Crop Research – Current and Emerging Methodologies

Author : Marta Sousa Silva
Publisher : Frontiers Media SA
Page : 181 pages
File Size : 20,81 MB
Release : 2019-11-18
Category :
ISBN : 2889631583

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The plant metabolome is highly complex, being composed of over 200,000 metabolites. The characterization of these small molecules has been crucial to study plant growth and development as well as their response to environmental changes. The potential of metabolomics in plant research, particularly if applied to crop plants, is also extremely valuable in the discovery of biomarkers and in the improvement of crop yield and quality. This Frontiers Research Topic addresses many applications of metabolomics to crop research, based on different analytical platforms, including mass spectrometry, and nuclear magnetic resonance. It comprises 13 articles from 109 authors that show the importance and the contribution of metabolomics in the analysis of crop’s traceability and genetic variation, in the study of fruit development, and in the understanding of the plant’s response to the environment and to different biotic and abiotic stresses.

Microbial Biofilms

Author : Chaminda Jayampath Seneviratne
Publisher : CRC Press
Page : 334 pages
File Size : 24,69 MB
Release : 2017-07-12
Category : Medical
ISBN : 1351646427

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Microbial Biofilms: Omics Biology, Antimicrobials and Clinical Implications is a comprehensive survey of microbial biofilms and their role in human health and disease with contributions from world renowned experts in molecular microbiology, proteomics, genomics, metabolomics and infectious diseases. The book is intended to serve as a guide for students, as well as a reference for researchers, clinicians and industry professionals. The chapters cover bacterial and fungal microbiomes, and the latest omics techniques organized in a clear and up-to-date manner. One of the highlights of this book is the comprehensive information on "omics of microbial biofilms". The chapters dedicated to metagenomics, proteomics and metabolomics are designed to provide a simple and holistic review of the current knowledge and, the applications of these techniques in the field of microbial biofilms. In addition to introductory chapters on microbial biofilms and their clinical implications, subsequent chapters delve into oral biofilms, their composition, and metagenomic diversity. Thereafter, mechanisms of drug resistance in microbial biofilms are reviewed, as well as the proteomic and metabolomic characterization of this resistance. The book includes a comprehensive discussion of persister cells and host–microbial interactions on mucosal surfaces. Finally, the book concludes with a summary of novel therapeutic approaches for biofilms such as synbiotics and biogenics.

Antimicrobial Resistance and Food Safety

Author : Chin-Yi Chen
Publisher : Elsevier
Page : 457 pages
File Size : 20,10 MB
Release : 2015-04-15
Category : Technology & Engineering
ISBN : 0128013370

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Antimicrobial Resistance and Food Safety: Methods and Techniques introduces antimicrobial resistant food-borne pathogens, their surveillance and epidemiology, emerging resistance and resistant pathogens. This analysis is followed by a systematic presentation of currently applied methodology and technology, including advanced technologies for detection, intervention, and information technologies. This reference can be used as a practical guide for scientists, food engineers, and regulatory personnel as well as students in food safety, food microbiology, or food science. Includes analysis of all major pathogens of concern Provides many case studies and examples of fundamental research findings Presents recent advances in methodologies and analytical software Demonstrates risk assessment using information technologies in foodborne pathogens

Emerging Modalities in Mitigation of Antimicrobial Resistance

Author : Nadeem Akhtar
Publisher : Springer Nature
Page : 569 pages
File Size : 29,37 MB
Release : 2022-01-31
Category : Medical
ISBN : 303084126X

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Antimicrobial resistance (AMR) is one of the deadliest threats to global public health. This book focuses on dynamics in the landscape of AMR while informing about the latest technologies and strategies to mitigate it. The menace of AMR in different niches, routes of penetration across various domains, socio-economic impact, and the need for a 'One Health' approach in mitigating AMR has been emphasized. Factors involved in AMR, underlying mechanisms, and pharmacometrics in developing antimicrobials are highlighted. Emphasis is given to emerging technologies that are sustainable, scalable, and applicable to the global community, such as big data analytics, bioactive agents, phage therapy, and nanotechnology. The book also explores current and alternative treatment strategies to combat AMR, emphasizing the use of nanoparticles to target pathogens and as a viable alternative to antibiotics.