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Author : Keith B. Elkon
Publisher : Karger Medical and Scientific Publishers
Page : 219 pages
File Size : 40,30 MB
Release : 2006
Category : Science
ISBN : 3805580363
This volume highlights the recent advances in the basic mechanisms of apoptosis and the application of that knowledge to understanding the impact of defective apoptosis or defective clearance of apoptotic cells on the immune function and the expression of
Author : Joachim R. Kalden
Publisher : John Wiley & Sons
Page : 392 pages
File Size : 48,34 MB
Release : 2006-03-06
Category : Medical
ISBN : 3527605290
This is the first comprehensive book about the relationship between apoptosis and autoimmune diseases. It offers a unique up-to-date overview on research results on the defective execution of apoptosis and the incomplete clearance of apoptotic cells. The molecular and cellular mechanisms involved are described in detail. As a possible consequence of apoptotic dysfunction, the development of severe autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus) is discussed. An outlook on future research topics includes the evaluation of novel therapeutic strategies.
Author : Dr. Martin Herrmann
Publisher : Wiley-VCH Verlag GmbH
Page : 381 pages
File Size : 11,81 MB
Release : 2003
Category : Medical
ISBN : 9783527304424
This is the first comprehensive book about the relationship between apoptosis and autoimmune diseases. It offers a unique up–to–date overview on research results on the defective execution of apoptosis and the incomplete clearance of apoptotic cells. The molecular and cellular mechanisms involved are described in detail. As a possible consequence of apoptotic dysfunction, the development of severe autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus) is discussed. An outlook on future research topics includes the evaluation of novel therapeutic strategies.
Author : Reginald Halaby
Publisher :
Page : pages
File Size : 37,4 MB
Release : 2012
Category :
ISBN : 9789535106937
Author : Andrzej Górski
Publisher : Springer Science & Business Media
Page : 209 pages
File Size : 49,6 MB
Release : 2012-12-06
Category : Medical
ISBN : 9401009813
This book presents an excellent review of the mechanisms underlying the phenomena of autoimmunity. It provides not only an update of the field's state of the art, but also presents new concepts in the fundamentals and treatment of autoimmune disorders. The finest example of the new approach is understanding the nature of autoimmunity and the treatment of autoimmune diseases is the introductory article. The author opposes the current dogma that autoimmune disorders should be treated with immunosuppressors, and postulates rather the activation of the immune system, which may lead to redirecting the immune response to the protective, Th-2 type of immunity. A series of articles deals with several aspects of the subject, such as the generation, progression, and regulation of autoimmune phenomena. The roles of pathogens, apoptosis, cytokines, complement components, and regulatory T cells are described, as well as the association between the immune and neurohormonal systems in major autoimmune disorders. This is not a textbook, but it is highly recommended for clinicians and university workers, and as supplementary reading for lecturers and students.
Author : Katerina Chatzidionysiou
Publisher : BoD – Books on Demand
Page : 212 pages
File Size : 19,66 MB
Release : 2015-06-17
Category : Medical
ISBN : 9535121340
Autoimmunity is defined as an immune response against a self-antigen. This abnormal immune response can lead to tissue damage and to the development of autoimmune disease. From organ-specific autoimmune diseases, such as myasthenia gravis, to non-organ-specific, such as systemic lupus erythematosus, autoimmune diseases represent a heterogeneous group of disorders which affect approximately 6% of the population. The pathogenesis of many autoimmune diseases is complex and remains not completely understood. The aim of this book is to present current knowledge regarding pathogenic mechanisms of autoimmune diseases, clinical aspects of specific autoimmune diseases, like vitiligo, celiac disease and autoimmune liver disease, as well as insights regarding specific therapies.
Author : Argyrios N Theofilopoulos
Publisher : CRC Press
Page : 1518 pages
File Size : 43,83 MB
Release : 2002-12-06
Category : Science
ISBN : 9789057026454
Remarkable advances have been made in the pathogenesis of autoimmunity, such as with bone marrow transplantation, which is becoming a powerful strategy in treating certain life-threatening diseases. The Molecular Pathology of Autoimmune Diseases is a concise and centralized resource for information on the topic, with a special focus on the molecular and genetic basis of these disorders. Dozens of international experts devote themselves to illuminating the reader in this volume, with discussions on the basic aspects of autoimmune processes to systemic and organ-specific diseases. This volume is an invaluable reference to students and professionals in immunology and related fields.
Author : Clio Mavragani
Publisher : BoD – Books on Demand
Page : 506 pages
File Size : 36,43 MB
Release : 2011-10-26
Category : Medical
ISBN : 9533076437
The present edition entitled "Autoimmune disorders - Pathogenetic aspects" aims to present the current available evidence of etiopathogenetic insights of both systemic and organ specific autoimmune disorders, the crossover interactions among autoimmunity, cardiovascular morbidity and malignancy as well as novel findings in the exciting fields of osteoimmunology and immunology of pregnancy.
Author : M. Eric Gershwin
Publisher : Academic Press
Page : 1302 pages
File Size : 45,8 MB
Release : 2013-12-03
Category : Medical
ISBN : 0123849306
Since publication of the 4th Edition of The Autoimmune Diseases in 2006, the understanding of the immune mechanisms underlying autoimmunity and autoimmune disease has significantly deepened and broadened. This fully revised 5th Edition incorporates new material and combines common themes underlying inductive and effector mechanisms and therapies that relate generally to the autoimmune disorders. It discusses the biological basis of disease at genetic, molecular, cellular, and epidemiologic levels and includes expanded coverage of autoinflammatory disease and autoimmune responses to tumors. Gives a thorough and an important overview on the entire field, framing individual disease chapters with information that compares and contrasts each disorder and therapy Provides thorough, up-to-date information on specific diseases, along with clinical applications, in an easily found reference for clinicians and researchers interested in certain diseases Keeps readers abreast of current trends and emerging areas in the field Ensures that content is not only up-to-date, but applicable and relevant
Author : Moncef Zouali
Publisher : IOS Press
Page : 378 pages
File Size : 48,26 MB
Release : 2003
Category : Autoimmune diseases
ISBN : 9781586033613