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Clinical application of antithrombotic therapy in both arterial disease (acute coronary syndromes, acute MI, peripheral arterial disease, valvular heart disease, atrial fibrillation) and venous disease, (venous thromboembolic disease and pulmonary embolism). Results of major clinical trials and their implications for clinical practice.
An essential companion for busy professionals seeking to navigate stroke-related clinical situations successfully and make quick informed treatment decisions.
Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
In the last years, indications for defibrillators and cardiac resynchronization therapy have expanded enormously; for this reason, and also due to the extension of human life length, the number of patients with implanted cardiac devices have steadily increased. The leads implanted for the functioning of these devices, however, have a limited duration in time and more and more their extraction will be a frequent issue in clinical practice, in order to treat short- and long-term complications, such as infections and failures. Aim of this book is to provide readers with a state-of-the-art on lead extraction techniques. The chapters deal with leads characteristics, indications to lead removal, patient preparation, tools and techniques for extraction, and prevention and management of complications. In addition, a series of tips and tricks on how to treat some particular conditions (tight cost-clavicular space, fractured leads, ICD leads, dangered leads...etc.), are given. A new extracting technique, according to which the extraction is performed through the internal jugular vein is described; several examples are included and many figures provide a thorough depiction of this innovative procedure. The volume will be an excellent resource for all those involved in the management of cardiac patients: cardiologists, arrhythmologists, cardiac surgeons, GPs, pediatricians, and post-graduate students in these disciplines.
Intravascular thrombus formation remains one of the most significant problems in cardiovascular medicine. It underlies the clinical presentation of acute coronary syndromes, including unstable angina and non-ST-segment elevation myocardial infarction (NSTEMI) and ST-segment elevation myocardial infarction. More and more individuals are stricken with an acute MI and undergo a percutaneous coronary intervention (PCI). Several reasons apply, including an increasingly aged population, the growing burden of chronic risk factors such as diabetes, obesity, sedentary behaviour, and improvements in early recognition and intervention. Thrombus formation also results in substantial morbidity and mortality. Despite significant advances in prevention and treatment of venous thromboembolism, pulmonary embolism remains a common preventable cause of hospital deaths. Implementing the most appropriate, and safe, anticoagulation therapy across the spectrum of cardiovascular disease in the presence of a wide range of other risk factors remains a challenge. Written by leading authorities in the field, Management Strategies in Antithrombotic Therapy offers a comprehensive review of antithrombotic therapy, including the latest therapies, risk factors and evidence-based strategy. The book acquaints readers with the data behind the commonly used antithrombotic agents and assists them in formulating a sound, evidence-based therapeutic strategy appropriate for each patient. This book is an invaluable resource for all postgraduate students and specialist physicians in cardiovascular medicine, cardiac and vascular surgery, and critical care.
Highly Commended by the BMA Medical Book Awards for Internal Medicine! Written and edited by internationally renowned specialists, the third edition of Gastroenterological Endoscopy covers the entire spectrum of diagnostic and therapeutic procedures for the upper and lower GI tract while providing the latest overview of GI disorders. A great wealth of high-resolution photographs provides the visual information needed to confidently assess and diagnose mucosal lesions of the entire digestive tract. Significant advances in the field—both medical and technical—since the last edition are covered in comprehensive detail. Key Features: New panel of top international editors, continuing the tradition of excellence, depth, and breadth as originated by founding editors Classen, Tytgat, and Lightdale; list of contributing authors is a "who's who" of GI endoscopy Coverage of newest, advanced tools and techniques: gastric-POEMS, submucosal tunnel endoscopic resection (STER), lumen-apposing metal stents, "over-the-scope" clips, and much more More than 750 exquisite images Gastroenterological Endoscopy, third edition, surely deserves a prominent place in any complete endoscopy reference collection.
This book presents the latest evidence and guidelines supporting the use of anticoagulant therapy for various clinical scenarios. The field of anticoagulation therapy is evolving rapidly, particularly since the arrival and widespread adoption of direct oral anticoagulants. Organized in two parts, this book reviews the pharmacologic properties of various anticoagulants and details the clinical applications of anticoagulant therapy. Drugs such as warfarin and unfractionated heparin, as well as parenteral and direct oral anticoagulants are discussed in terms of their pharmacokinetics, drug-disease interactions, dosing strategies, and risk considerations. Clinical applications of anticoagulant therapy in disorders such as acute coronary syndromes, atrial fibrillation, and thrombophilia and in special populations such as pregnant women, the elderly, and in the patient with cancer are highlighted. Clinical vignettes, algorithms, clinical pearls, and self-assessment questions are integrated throughout the book. Featuring contributions from authorities in the field, Anticoagulation Therapy is an essential resource for cardiologists, vascular medicine specialists, hematologists, internists, and all other healthcare professionals who prescribe anticoagulants.
Thrombosis can be prevented and treated effectively by a variety of pharmacologic agents. This monograph provides a summary of the 2003 American College of Chest Surgeons Recommendations for pharmacologic agents, together with a brief review of the background data on which the therapeutic recommendations are based.
Thoroughly revised, this handy manual is filled with practical advice for the entire cardiac care team. It covers all aspects of care of the surgical heart patient-from preoperative assessment to postoperative management to treatment protocols. Chapters written by both nurses and doctors emphasize the critical care team approach to cardiac surgery to improve patient outcomes and provide useful, practical information for every clinical setting. A logical organization, including individual sections on preoperative, operative, and postoperative issue speeds to the information you need. The latest details on coronary artery disease . fluid, electrolyte, and renal function . management of postoperative cardiac arrhythmias . mechanical devices . and postoperative myocardial ischemia enhance your clinical acumen. An updated appendix of Management Summaries keeps you current on the latest in care. New images and line drawings illuminate key steps to help you master every procedure.
Author : Margaret C. Fang Publisher : John Wiley & Sons Page : 348 pages File Size : 39,91 MB Release : 2011-10-07 Category : Medical ISBN : 1118067169
The first practical guide for hospitalists on the use of anticoagulants in hospitalized patients This edited volume provides a comprehensive overview of the vital topic of anticoagulation in the hospital setting. Designed specifically for use by hospital-based clinicians and associated hospital-based staff, this fully evidence-based book addresses the most commonly used anticoagulant agents, the latest advances in anticoagulation drugs, and primary indications for their use at therapeutic levels. This thorough, easy-to-use reference summarizes the most important guidelines and medical literature on anticoagulation. It features a careful review of the epidemiology and treatment of complications associated with anticoagulants. Unique topics include transition of care and practical strategies for developing and implementing quality improvement programs to enhance the administration and safety of anticoagulants. This concise resource also covers: Antiplatelet medications The treatment and prevention of venous thromboembolism in medical patients Venous thromboembolism prophylaxis in surgical patients Peri-operative management of oral anticoagulants and antiplatelet agents Prevention of cardioembolic stroke Antithrombotics for ischemic stroke Antithrombotic therapy for non-ST elevation acute coronary syndrome Hemorrhagic complications of anticoagulants in hospitalized patients Heparin-induced thrombocytopenia Hospitalists and other members of the patient care team will find that Inpatient Anticoagulation answers their questions with dependable and timely information.