[PDF] Anti Aging Drugs eBook

Author : Alexander M Vaiserman
Publisher : Royal Society of Chemistry
Page : 592 pages
File Size : 10,35 MB
Release : 2017-02-01
Category : Health & Fitness
ISBN : 178262435X

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Aging is a natural phenomenon that is peculiar to all living things. However, accumulating findings indicate that senescence could be postponed or prevented by certain approaches. Substantial evidence has emerged supporting the possibility of radical human health and lifespan extension, in particular through pharmacological modulation of aging. A number of natural dietary ingredients and synthetic drugs have been assumed to have geroprotective potential. In the development of anti-aging therapeutics, several cell, insect, and animal models may provide useful starting points prior to human studies. This book provides an overview of current research aimed to search for life-extending medications and describes pharmacological aspects of anti-aging medicine. Readers are introduced to the fascinating historical background of geroprotection in the first chapter. In-depth information on models for investigating geroprotective drugs precedes a section covering anti-aging properties of pharmaceutical compounds, such as calorie restriction mimetics, autophagy inducers, senolytics and mitochondrial antioxidants. Finally, strategies to translate discoveries from aging research into drugs and healthcare policy perspectives on anti-ageing medicine are provided to give a complete picture of the field. A timely and carefully edited collection of chapters by leading researchers in the field, this book will be a fascinating and useful resource for pharmacologists, gerontologists and any scientifically interested person wishing to know more about the current status of research into anti-aging remedies, challenges and opportunities.

Author : Astrid Stuckelberger
Publisher : vdf Hochschulverlag AG
Page : 330 pages
File Size : 29,45 MB
Release : 2008
Category : Aging
ISBN : 3728131954

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The 21st century technological development is revolutionizing medicine and health care, bringing new hopes to human suffering by offering cures and treatments which were unthinkable a few decades ago. This is where anti-ageing medicine finds its niche. Anti-ageing medicine aims at slowing, arresting, and reversing phenomena associated with ageing by merging biotechnological innovation and engineered solutions. Ideally, by means of the newest medical technology, the "body machinery" should be kept fit and at peak performance all life long. Early detection of age-related dysfunction should thus be "fixed" at any age with interventions such as metabolic fine tuning, enhancement, regeneration, restoration or replacement of "body parts" (i.e. organs, skin, bone or muscle). It covers a vast array of domains: from cell therapy to pharmaceutical interventions, from bio-surgery to aesthetic surgery, from human enhancement to fortified food, from smart housing and robots to toxic-free environments. Anti-ageing medicine holds promises but also significant risks and safety issues which are addressesd in this book. It presents the latest scientific evidence on what works or does not work. It also provides public policy recommendations to ensure the protection of consumers and their rights while encouraging research and development. This book is intended for academics, health professionals, business persons, consumers and policy-makers interested in the latest evidence and ethical issues about anti-ageing medicine.

Author : Theodore Goldsmith
Publisher : Azinet Press
Page : 138 pages
File Size : 23,95 MB
Release : 2020-08-29
Category : Health & Fitness
ISBN : 9780978870966

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Aging is a treatable condition! For more than a century aging and a particular lifespan have been widely thought to be an inescapable and fundamental aspect of human existence. Indeed, Darwin's evolution theory tells us that the force of evolution is toward defeating aging, leading to the idea that aging is the result of unalterable laws of physics or chemistry. We can find different treatments for different age-related diseases like cancer and heart disease but aging is itself an untreatable fact of life. Today it is increasingly clear that aging is actually the result of complex biological programs that purposely limit lifespan in humans and most animals because this created an evolutionary advantage for populations of wild animals including our prehistoric ancestors. Programmed aging and supporting evolutionary concepts are a logical consequence of relatively recent discoveries in genetics as well as observations regarding the aging and lifespan characteristics of many different organisms. As a consequence, we can increase healthy human lifespan by interfering with the aging program. Interfering with a biological process is a familiar problem in medicine, and research toward developing treatments based on this idea are underway. Goldsmith describes the 160-year history of still-unresolved scientific arguments over the evolutionary nature of aging, the increasing empirical evidence of aging programs, and the exciting prospects for lifespan extension and healthy living. More practically, the book describes: Key observations about the nature of aging. Orally administered substances known to increase longevity in mice. Why exercise increases longevity. Anti-aging medicine issues with existing health care systems. Social, educational, ethical, and economic issues with extending lifespan. How lifespan extension concepts add to our ability to devise treatments for age-related diseases. Contents 1. Introduction 2. Nature of Aging and Lifespan 3. Evolution Theory and Aging 4. Evidence Supporting Programmed Aging 5. U.S. Health System Summary 6. Exercise and Activity - Effects on Aging 7. Non-Science Factors Favor Non-Programmed Aging 8. Programmed vs Non-Programmed Aging - Current Status 9. Anti-Aging Research 10. Anti-Aging Medicine 11. Conclusion 12. Free Resources and Further Reading 13. Author's Notes 14. Appendix 15. Glossary 16. References

Author : Vitaly Koltover
Publisher : Academic Press
Page : 400 pages
File Size : 13,75 MB
Release : 2022-12-07
Category : Medical
ISBN : 0128236809

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Anti-Aging Pharmacology provides an overview of current research aimed at the pharmacological modulation of aging, including a discussion of the growing number of novel drug classes with promising anti-aging potential. The aging process is the main risk factor for all chronic diseases affecting the elderly. With lifespans extending across the globe, these chronic diseases are placing a larger burden on individuals and health care systems. Therefore, slowing down the aging rate could be more effective in delaying aging-associated chronic disorders than combating them one by one, which is the conventional approach in a current disease-based pharmacological paradigm. This book contains the work of the world’s leading researchers in the field, including sections on the conceptual and methodological background of anti-aging pharmacology, the basic classes of anti-aging drugs, phytochemicals, outcomes of anti-aging developments and future directions. This book will be of interest to a wide audience, ranging from pharmacologists, medicinal chemists and academic researchers in gerontology, biomedical sciences and those in medical practice. Includes updated information about current developments in anti-aging pharmacology Offers practical advice on the applicability of certain healthspan-promoting medications Discusses potential challenges related to the translation of anti-aging drugs in clinical practice

Author : Andrew Steele
Publisher : Anchor
Page : 353 pages
File Size : 33,72 MB
Release : 2021-03-23
Category : Science
ISBN : 0385544936

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“A fascinating look at how scientists are working to help doctors treat the aging process itself, helping us all to lead longer, healthier lives.” —Sanjay Gupta, MD Aging—not cancer, not heart disease—is the underlying cause of most human death and suffering. The same cascade of biological changes that renders us wrinkled and gray also opens the door to dementia and disease. We work furiously to conquer each individual disease, but we never think to ask: Is aging itself necessary? Nature tells us it is not: there are tortoises and salamanders who are spry into old age and whose risk of dying is the same no matter how old they are, a phenomenon known as “biological immortality.” In Ageless, Andrew Steelecharts the astounding progress science has made in recent years to secure the same for humans: to help us become old without getting frail, to live longer without ill health or disease.

Author : Dr. Marios Kyriazis
Publisher : Watkins Media Limited
Page : 167 pages
File Size : 48,76 MB
Release : 2012-01-01
Category : Health & Fitness
ISBN : 1780283008

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An in-depth analysis of the benefits, limitations and side effects of the most commonly used anti-ageing medicines.

Author : Sandeep Kumar Singh
Publisher : Academic Press
Page : 411 pages
File Size : 50,68 MB
Release : 2022-07-19
Category : Medical
ISBN : 0323902367

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Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging is a comprehensive and timely book on all aspects of anti-aging strategies. The book provides comprehensive, foundational knowledge on the mechanisms of aging and current anti-aging strategies and approaches developed. Aging research has experienced an unprecedented advance over recent years with the discovery that the rate of aging is determined, at least to some extent, mainly by our genetics and modulated by environmental factors. The hallmarks of aging describe the molecular and cellular processes that govern biological aging and their variation in individuals. Covers different aspects of anti-aging research, from foundational knowledge to future perspectives Provides understanding on the different hallmarks of aging and how they can be applied in the development of anti-aging drugs Discusses various anti-aging strategies, including telomerase reactivation, clearance of senescent cells, stem cell-based therapy, and others

Author : J. Robin Harris
Publisher : Springer
Page : 499 pages
File Size : 12,56 MB
Release : 2019-03-19
Category : Medical
ISBN : 9811336814

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This volume of the subcellular Biochemistry series will attempt to bridge the gap between the subcellular events that are related to aging as they were described in the first volume of this set of two books and the reality of aging as this is seen in clinical practice. All chapters will start from the biochemistry or cell biology, where the data is available and work up towards the understanding that we have of aging in the various areas that are related to the subject. Key focus points for this volume are nutrition, external factors and genetics on aging. There will also be chapters that will focus on various organs or tissues in which aging has been well studied, like the eyes, the muscles, the immune system and the bones. The aim of the book project and the book project that is published in concert with this volume is to bring the subcellular and clinical areas into closer contact.