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AIDS Epidemiology

Author : Ron Brookmeyer
Publisher : Oxford University Press
Page : 374 pages
File Size : 30,10 MB
Release : 1994-01-06
Category : Medical
ISBN : 0199748748

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AIDS has appeared in more than 130 countries, and over 100,000 cases of AIDS have been reported in the U.S. alone. More and more, the public will be depending on statisticians to provide answers about the future course of this epidemic. This comprehensive work confronts the problems that are unique to AIDS research and unites them under a single conceptual framework. It focuses on methods for the design and analysis of epidemiologic studies, the natural history of AIDS and the transmission of HIV, methods for tracking and projecting the course of the epidemic, and statistical issues in therapeutic trials. The various methods of monitoring and forecasting this disease receive comprehensive treatment. These methods include back-calculation, which the authors developed; interpretation of survey data on HIV prevalence; mathematical models for HIV transmission; and approaches that combine different types of epidemiological data. Much of this material -- such as a discussion of methods for assessing safety of the blood supply, an evaluation of survey approaches, and methods to project pediatric AIDS incidence -- is not available in any other work.

Preventing HIV Transmission

Author : National Research Council and Institute of Medicine
Publisher : National Academies Press
Page : 352 pages
File Size : 30,12 MB
Release : 1995-09-14
Category : Medical
ISBN : 0309176212

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This volume addresses the interface of two major national problems: the epidemic of HIV-AIDS and the widespread use of illegal injection drugs. Should communities have the option of giving drug users sterile needles or bleach for cleaning needs in order to reduce the spread of HIV? Does needle distribution worsen the drug problem, as opponents of such programs argue? Do they reduce the spread of other serious diseases, such as hepatitis? Do they result in more used needles being carelessly discarded in the community? The panel takes a critical look at the available data on needle exchange and bleach distribution programs, reaches conclusions about their efficacy, and offers concrete recommendations for public policy to reduce the spread of HIV/AIDS. The book includes current knowledge about the epidemiologies of HIV/AIDS and injection drug use; characteristics of needle exchange and bleach distribution programs and views on those programs from diverse community groups; and a discussion of laws designed to control possession of needles, their impact on needle sharing among injection drug users, and their implications for needle exchange programs.

Preventing and Mitigating AIDS in Sub-Saharan Africa

Author : National Research Council (U.S.). Panel on Data and Research Priorities for Arresting AIDS in Sub-Saharan Africa
Publisher : National Academies
Page : 36 pages
File Size : 33,86 MB
Release : 1996-01-01
Category : Medical
ISBN :

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The AIDS epidemic in Sub-Saharan Africa continues to affect all facets of life throughout the subcontinent. Deaths related to AIDS have driven down the life expectancy rate of residents in Zambia, Kenya, and Uganda with far-reaching implications. This book details the current state of the AIDS epidemic in Africa and what is known about the behaviors that contribute to the transmission of the HIV infection. It lays out what research is needed and what is necessary to design more effective prevention programs.

Disease Control Priorities, Third Edition (Volume 6)

Author : King K. Holmes
Publisher : World Bank Publications
Page : 1027 pages
File Size : 46,36 MB
Release : 2017-11-06
Category : Medical
ISBN : 1464805253

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Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

HIV/AIDS in the Post-HAART Era

Author : John C. Hall
Publisher : PMPH-USA
Page : 1052 pages
File Size : 43,1 MB
Release : 2011
Category : AIDS (Disease)
ISBN : 9781607951056

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The science of the virus and its effects and the clinical approaches to its treatment and transmission prevention are placed in the context of the history and epidemiology of the HIV-AIDS pandemic. Each organ system of the body is explored as to manifestations of the disease, treatment now and in the future, as well as what the disease has taught us about the immune response. The science of epidemiology, which is so important in allowing for tracking of the disease and potential limitation of transmission, is another aspect of AIDS explored in detail. The pandemic manifests differently in different parts of the world, and the relevance of the volume is enhanced by its international group of contributors. No other text provides the historical and epidemiological context of this disease along with an update of diagnosis and treatment. The underlying science and epidemiology of AIDS are not neglected, so the student or clinician who is treating patients with AIDS can gain a full understanding of HIV/AIDS in individual patients and in their communities.

HIV and AIDS in Africa

Author : Ezekiel Kalipeni
Publisher : Wiley-Blackwell
Page : 416 pages
File Size : 33,68 MB
Release : 2003-11-21
Category : Social Science
ISBN : 9780631223573

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HIV and AIDS in Africa: Beyond Epidemiology is a collection that seeks to further our understanding of AIDS by shifting the predominant understandings generated by biomedical and epidemiological research. Brings together international contributors---including often overlooked African scholars and activists---from across the social sciences to examine HIV and AIDS from angles previously unexplored. By presenting on-the-ground evidence and ethnographic cases, emphasizes that HIV transmission in sub-Saharan Africa is a complex and regionally specific phenomenon rooted in local economies, deepening poverty, migration, gender, war, global economies, and cultural politics. Recognizes that AIDS in Africa cannot be stemmed until social, gender, and economic inequities are addressed in meaningful ways.

Modeling HIV Transmission and AIDS in the United States

Author : Herbert W. Hethcote
Publisher : Springer Science & Business Media
Page : 243 pages
File Size : 31,60 MB
Release : 2013-03-09
Category : Mathematics
ISBN : 3642514774

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The disease that came to be called acquired immunodeficiency syndrome (AIDS) was first identified in the summer of 1981. By that time, nearly 100,000 persons in the United States may have been infected with human immunodeficiency virus (HIV). By the time the routes of transmission were clearly identified and HIV was established as the cause of AIDS in 1983, over 300,000 people may have been infected. That number has continued to increase, with approximately 1,000,000 Americans believed to be infected in 1991. The epidemic is of great public health concern because HlV is infectious, causes severe morbidity and death in most if not all of those infected, and often occurs in relatively young persons. In addition, the cost of medical care for a person with HIV disease is high, and the medical care needs of HIV-infected persons place a severe burden on the medical care systems in many areas. Understanding and controlling the HIV epidemic is a particularly difficult challenge. The long and variable period between HIV infection and clinical disease makes it difficult both to forecast the future magnitude of the epidemic, which is important for health care planning, and to estimate the number infected in the last several years, which is important for monitoring the current status of the epidemic.

The Social Impact of AIDS in the United States

Author : National Research Council
Publisher : National Academies Press
Page : 337 pages
File Size : 36,72 MB
Release : 1993-02-01
Category : Medical
ISBN : 0309046289

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Europe's "Black Death" contributed to the rise of nation states, mercantile economies, and even the Reformation. Will the AIDS epidemic have similar dramatic effects on the social and political landscape of the twenty-first century? This readable volume looks at the impact of AIDS since its emergence and suggests its effects in the next decade, when a million or more Americans will likely die of the disease. The Social Impact of AIDS in the United States addresses some of the most sensitive and controversial issues in the public debate over AIDS. This landmark book explores how AIDS has affected fundamental policies and practices in our major institutions, examining: How America's major religious organizations have dealt with sometimes conflicting values: the imperative of care for the sick versus traditional views of homosexuality and drug use. Hotly debated public health measures, such as HIV antibody testing and screening, tracing of sexual contacts, and quarantine. The potential risk of HIV infection to and from health care workers. How AIDS activists have brought about major change in the way new drugs are brought to the marketplace. The impact of AIDS on community-based organizations, from volunteers caring for individuals to the highly political ACT-UP organization. Coping with HIV infection in prisons. Two case studies shed light on HIV and the family relationship. One reports on some efforts to gain legal recognition for nonmarital relationships, and the other examines foster care programs for newborns with the HIV virus. A case study of New York City details how selected institutions interact to give what may be a picture of AIDS in the future. This clear and comprehensive presentation will be of interest to anyone concerned about AIDS and its impact on the country: health professionals, sociologists, psychologists, advocates for at-risk populations, and interested individuals.

Mathematical and Statistical Approaches to AIDS Epidemiology

Author : Carlos Castillo-Chavez
Publisher : Springer Science & Business Media
Page : 416 pages
File Size : 48,93 MB
Release : 2013-03-13
Category : Medical
ISBN : 3642934544

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The 18 research articles of this volume discuss the major themes that have emerged from mathematical and statistical research in the epidemiology of HIV. The opening paper reviews important recent contributions. Five sections follow: Statistical Methodology and Forecasting, Infectivity and the HIV, Heterogeneity and HIV Transmission Dynamics, Social Dynamics and AIDS, and The Immune System and The HIV. In each, leading experts in AIDS epidemiology present the recent results. Some address the role of variable infectivity, heterogeneous mixing, and long periods of infectiousness in the dynamics of HIV; others concentrate on parameter estimation and short-term forecasting. The last section looks at the interaction between the HIV and the immune system.

Confronting AIDS

Author : National Academy of Sciences
Publisher : National Academies Press
Page : 393 pages
File Size : 48,82 MB
Release : 1986-02-01
Category : Medical
ISBN : 0309036992

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This volume examines the complex medical, social, ethical, financial, and scientific problems arising from the AIDS epidemic and offers dozens of public policy and research recommendations for an appropriate national response to this dread disease.