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"From its foundation some 60 years ago, right up to the present day, woman scientists trained at the MRC Laboratory of Molecular Biology (LMB) in Cambridge, UK have produced outstanding work, and many have gone on to stellar careers at the world's foremost scientific institutions. This book showcases the scientific achievements of some of these pioneers, describing the work they have done within the context of their lives outside the lab. Their stories demonstrate how these two competing priorities can be combined into a successful whole"--
"Astronomy was the earliest science in which women's participation has been recorded. Enheduanna, the Mezopotanian priestess around 2350 BCE monitored the stars and Hypathia in the fourth century is especially famous. Women astronomers such as Sophia Brahe, Maria Cunitz, Elisabetha Hevelius, Maria Margaretha Kirch, and Caroline Herschel often worked alongside family members, husbands or brothers. The next generations were more independent, of them, Mary Somerville, Maria Mitchell, Williamina Fleming, and Nancy Grace Roman are mentioned. Vera C. Rubin had revolutionary ideas about the black holes whose real significance is recognized today. Jocelyn Bell Burnell helped in the discovery of pulsars for which her professor received the Nobel Prize. France A. Cordova was elevated to various top administrative positions. Finally, the astronomer Andrea M. Ghez received a share of the physics Nobel Prize for her work on black holes"--
Shane Crotty's biography of David Baltimore details the life and work of one of the most brilliant, powerful, and controversial scientists of our time. Although only in his early sixties, Baltimore has made major discoveries in molecular biology, established the prestigious Whitehead Institute at MIT, been president of Rockefeller University, won the Nobel Prize, and been vilified by detractors in one of the most scandalous and protracted investigations of scientific fraud ever. He is now president of Caltech and a leader in the search for an AIDS vaccine. Crotty not only tells the compelling story of this larger-than-life figure, he also treats the reader to a lucid account of the amazing revolution that has occurred in biology during the past forty years. Basing his narrative on many personal interviews, Crotty recounts the milestones of Baltimore's career: completing his Ph.D. at Rockefeller University in eighteen months, participating in the anti—Vietnam War movement, winning a Nobel Prize at age thirty-seven for the codiscovery of reverse transcriptase, and co-organizing the recombinant DNA/genetic engineering moratorium. Along the way, readers learn what viruses are and what they do, what cancer is and how it happens, the complexities of the AIDS problem, how genetic engineering works, and why making a vaccine is a complicated process. And, as Crotty considers Baltimore's public life, he retells the famous scientific fraud saga and Baltimore's vindication after a decade of character assassination. Crotty possesses the alchemical skill of converting technical scientific history into entertaining prose as he conveys Baltimore's huge ambitions, intensity, scientific genius, attitude toward science and politics, and Baltimore's own view about what happened in the "Baltimore Affair." Ahead of the Curve shows why with his complex personality, keen involvement in public issues, and wide-ranging interests David Baltimore has not only shaped the face of American science as we know it today, but has also become a presence in our culture.
This book tells the story of a professional problem-solving group that for more than 25 years has empowered its members by providing practical and emotional support. The objective of "Group," as Ellen Daniell and six other members call their bimonthly gatherings, is cooperation in a competitive world. And the objective of "Every Other Thursday" is to encourage those who feel isolated or stressed in a work or academic setting to consider the benefits of such a group--a group in which everyone is on your side.Each of the high-achieving individuals in Group (including members of the National Academy of Sciences, a senior scientist at a prestigious research institute, and university professors and administrators) has found the support of the others to be an essential part of her own success. Daniell provides detailed examples of how members help one another navigate career setbacks or other difficulties. She shows that group support, discussion, and application of common experience bring to light practical solutions and broader perspectives. In an inspirational conclusion, the author offers advice and practical guidelines for those who would like to establish a group of their own.
In 2007, the National Academy of Sciences (NAS) released Beyond Bias and Barriers: Fulfilling the Promise of Women in Academic Science and Engineering, an influential study suggesting that women face a hostile environment in the laboratory. The NAS report dismissed the possibi...
The Meaning of Success: Insights from Women at Cambridge makes a compelling case for a more inclusive definition of success. It argues that in order to recognise, reward and realise the talents of both women and men, a more meaningful definition of success is needed. Practical ways of achieving this are explored through interviews with female role models at the University of Cambridge. First-person stories bring alive the achievements and challenges women experience in their working lives, and the effect gender has on careers. The book stimulates a debate about how to bring about a more inclusive working environment.
Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.
This volume presents the latest collection of immunophenotypic techniques and applications used in research and clinical settings. Chapters in this book cover topics such as constructions of high dimensions fluorescence and mass cytometry panels; fluorescence barcoding; using dried or lyophilized reagents; and immunophenotypic examples of specific cell types. The book concludes with a discussion on the critical roles of quality control and immunophenotyping in the clinical environment. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Immunophenotyping: Methods and Protocols is a valuable resource for any researchers, clinician, or scientist interested in learning more about this evolving field.