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Stem Cells and the Future of Regenerative Medicine

Author : Institute of Medicine
Publisher : National Academies Press
Page : 112 pages
File Size : 49,37 MB
Release : 2002-01-25
Category : Science
ISBN : 0309170427

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Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Adult and Embryonic Stem Cells

Author : Kursad Turksen
Publisher : Springer Science & Business Media
Page : 267 pages
File Size : 50,7 MB
Release : 2012-02-03
Category : Science
ISBN : 1617796298

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This volume will cover a series of reviews on stem cells including adult and embryonic stem cells. Speakers were invited to present these talks during the Stem Cell Symposia in fall of 2010, in Samsun, Turkey. Unique aspect of this volume is that it brings a multidisciplinary aspect of stem cells extracted from a symposium.

Adult Stem Cell Research

Author : United States. Congress. Senate. Committee on Commerce, Science, and Transportation. Subcommittee on Science, Technology, and Space
Publisher :
Page : 82 pages
File Size : 18,2 MB
Release : 2013
Category : Federal aid to research
ISBN :

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Stem Cell Research

Author : Lillian E. Forman
Publisher : ABDO Publishing Company
Page : 114 pages
File Size : 41,58 MB
Release : 2007-09-01
Category : Juvenile Nonfiction
ISBN : 1617852627

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Discusses the controversial viewpoints regarding stem cell research.

Stem Cells

Author : Christine L. Mummery
Publisher : Academic Press
Page : 446 pages
File Size : 39,92 MB
Release : 2014-05-23
Category : Science
ISBN : 0124115675

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The second edition of Stem Cells: Scientific Facts and Fiction provides the non-stem cell expert with an understandable review of the history, current state of affairs, and facts and fiction of the promises of stem cells. Building on success of its award-winning preceding edition, the second edition features new chapters on embryonic and iPS cells and stem cells in veterinary science and medicine. It contains major revisions on cancer stem cells to include new culture models, additional interviews with leaders in progenitor cells, engineered eye tissue, and xeno organs from stem cells, as well as new information on "organs on chips" and adult progenitor cells. In the past decades our understanding of stem cell biology has increased tremendously. Many types of stem cells have been discovered in tissues that everyone presumed were unable to regenerate in adults, the heart and the brain in particular. There is vast interest in stem cells from biologists and clinicians who see the potential for regenerative medicine and future treatments for chronic diseases like Parkinson's, diabetes, and spinal cord lesions, based on the use of stem cells; and from entrepreneurs in biotechnology who expect new commercial applications ranging from drug discovery to transplantation therapies. Explains in straightforward, non-specialist language the basic biology of stem cells and their applications in modern medicine and future therapy Includes extensive coverage of adult and embryonic stem cells both historically and in contemporary practice Richly illustrated to assist in understanding how research is done and the current hurdles to clinical practice

Stem Cell Research

Author : David E. Newton
Publisher : Facts on File
Page : 284 pages
File Size : 16,59 MB
Release : 2007
Category : Medical
ISBN : 9780816065769

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One of the most controversial debates in scientific research today focuses on the use of embryonic stem cells in medical research. Recent discoveries suggest that stem cells exist within embryos and are even more plastic than adult cells, meaning that they are capable of developing into virtually any type of cell found in a living body. This discovery has raised the possibility of using embryonic stem cells for the treatment of a host of medical conditions, including Parkinson's and Alzheimer's diseases, spinal cord injuries, strokes, burns, heart disease, diabetes, osteoarthritis, and rheumatoid arthritis. In each instance, the transplantation of embryonic stem cells into the patient's body is expected to result in the growth of healthy new tissue or organs that have been damaged by the disease being treated. However, opponents of this scientific procedure doubt the validity of the scientific premises behind these therapeutic uses and oppose the destruction of human embryos for further research. Current federal law and regulations allow researchers to use federal funds to conduct some types of stem cell research using adult stem cells, but not embryonic stem cells, which significantly slows the progress of this possibly life-altering medical study. Exploring the political and ethical issues associated with this area of study, Stem Cell Research gives students and general readers alike a comprehensive look at both the science and the controversy surrounding this groundbreaking research. This first-stop reference provides clear and essential information needed to define, understand, and research this important issue objectively. Covering court cases, legislation, and relevant policies, this volume also includes a chronology; a glossary; a guide to further research; an annotated bibliography, an integral part of the Library in a Book series; appendixes; as well as an index.

Adult Stem Cell Standardization

Author : Paolo Di Nardo
Publisher : River Publishers
Page : 262 pages
File Size : 21,32 MB
Release : 2011
Category : Medical
ISBN : 8792329748

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The ambitious goal of this book is to gather the most innovative and scientifically robust knowledge and technologies on stem cells and involve investigators from academy and industry in formulating recommendations to standardize the isolation and manipulation of stem cells using solid and well-documented knowledge.

Perinatal Stem Cells

Author : Anthony Atala
Publisher : Academic Press
Page : 438 pages
File Size : 39,86 MB
Release : 2018-06-14
Category : Medical
ISBN : 0128120630

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Perinatal Stem Cells provides researchers and clinicians with a comprehensive description of the current clinical and pre-clinical applications of stem cells derived from perinatal sources, such as amniotic fluid, placenta and placental membranes, the umbilical cord and Wharton’s jelly. It's compiled by leading experts in the field, offering readers detailed insights into sources of perinatal stem cells and their potential for disease treatment. Therapeutic applications of perinatal stem cells include the treatment of in utero and pregnancy related diseases, cardiac disease, liver disease, pulmonary disease, inflammatory diseases, for hematopoietic regeneration, and for neural protection after stroke or traumatic brain injury. In addition, the rapid advance in clinical translation and commercialization of perinatal stem cell therapies is highlighted in a section on Clinical and Industry Perspective which provides insight into the new opportunities and challenges involved in this novel and exciting industry. Explores current clinical and pre-clinical application of stem cells derived from perinatal sources Offers detailed insight into sources of perinatal stem cells and their potential for disease treatment Discusses progress in the manufacturing, banking and clinical translation of perinatal stem cells Edited by a world-renowned team to present a complete story of the development and promise of perinatal stem cells

Stem Cells in Reproductive Medicine

Author : Carlos Simón
Publisher : Cambridge University Press
Page : 199 pages
File Size : 27,49 MB
Release : 2013-07-04
Category : Medical
ISBN : 1107034477

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Stem cell science has the potential to impact human reproductive medicine significantly - cutting edge technologies allow the production and regeneration of viable gametes from human stem cells offering potential to preciously infertile patients. Written by leading experts in the field Stem Cells in Reproductive Medicine brings together chapters on the genetics and epigenetics of both the male and female gametes as well as advice on the production and regeneration of gene cells in men and women, trophoblasts and endometrium from human embryonic and adult stem cells. Although focussing mainly on the practical elements of the use of stem cells in reproductive medicine, the book also contains a section on new developments in stem cell research. The book is essential reading for reproductive medicine clinicians, gynecologists and embryologists who want to keep abreast of practical developments in this rapidly developing field.

Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research

Author : National Research Council
Publisher : National Academies Press
Page : 112 pages
File Size : 44,92 MB
Release : 2007-03-22
Category : Medical
ISBN : 0309179602

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It is widely understood that stem cell treatments have the potential to revolutionize medicine. Because of this potential, in 2004 California voters approved Proposition 71 to set up a 10-year, $3 billion program to fund research on stem cells. Under the direction of the California Institute for Regenerative Medicine, this program will pay to build facilities for stem cell research and will fund doctors and scientists to carry out research with the ultimate goal of helping to develop therapies based on stem cells. For this research to move forward, however, will require a steady supply of stem cells, particularly human embryonic stem cells. Those stem cells are collected from developing human embryos created from eggs-or oocytes-harvested from the ovaries of female donors. Thus much of the promise of stem cells depends on women choosing to donate oocytes to the research effort. The oocyte donation process is not without risk, however. Donors are given doses of hormones to trigger the production of more eggs than would normally be produced, and this hormone treatment can have various side effects. Once the eggs have matured in the ovary, they must be retrieved via a surgical procedure that is typically performed under anesthesia, and both the surgery and the anesthesia carry their own risks. Furthermore, given the very personal nature of egg donation, the experience may carry psychological risks for some women as well. With this in mind, in 2006 the California Institute for Regenerative Medicine contracted with the National Academies to organize a workshop that would bring together experts from various areas to speak about the potential risks of oocyte donation and to summarize what is known and what needs to be known about this topic. The Committee on Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research was formed to plan the workshop, which was held in San Francisco on September 28, 2006. This report is a summary and synthesis of that workshop.