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Subcortical Structures and Cognition

Author : Leonard F. Koziol
Publisher : Springer Science & Business Media
Page : 415 pages
File Size : 49,68 MB
Release : 2009-04-21
Category : Psychology
ISBN : 0387848681

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Clinical psychologists and neuropsychologists are traditionally taught that cognition is mediated by the cortex and that subcortical brain regions mediate the coordination of movement. However, this argument can easily be challenged based upon the anatomic organization of the brain. The relationship between the prefrontal cortex/frontal lobes and basal ganglia is characterized by loops from these anterior brain regions to the striatum, the globus pallidus, and the thalamus, and then back to the frontal cortex. There is also a cerebrocerebellar system defined by projections from the cerebral cortex to the pontine nuclei, to the cerebellar cortex and deep cerebellar nuclei, to the red nucleus and then back to thalamus and cerebral cortex, including all regions of the frontal lobes. Therefore, both the cortical-striatal and cortical-cerebellar projections are anatomically defined as re-entrant systems that are obviously in a position to influence not only motor behavior, but also cognition and affect. This represents overwhelming evidence based upon neuroanatomy alone that subcortical regions play a role in cognition. The first half of this book defines the functional neuroanatomy of cortical-subcortical circuitries and establishes that since structure is related to function, what the basal ganglia and cerebellum do for movement they also do for cognition and emotion. The second half of the book examines neuropsychological assessment. Patients with lesions restricted to the cerebellum and/or basal ganglia have been described as exhibiting a variety of cognitive deficits on neuropsychological tests. Numerous investigations have demonstrated that higher-level cognitive functions such as attention, executive functioning, language, visuospatial processing, and learning and memory are affected by subcortical pathologies. There is also considerable evidence that the basal ganglia and cerebellum play a critical role in the regulation of affect and emotion. These brain regions are an integral part of the brain’s executive system. The ability to apply new methodologies clinically is essential in the evaluation of disorders with subcortical pathology, including various developmental disorders (broadly defined to include learning disorders and certain psychiatric conditions), for the purpose of gaining greater understanding of these conditions and developing appropriate methodologies for treatment. The book is organized around three sources of evidence: neuroanatomical connections; patients with various disease processes; experimental studies, including various imaging techniques. These three sources of data present compelling evidence that the basal ganglia and cerebellum are involved in cognition, affect, and emotion. The question is no longer if these subcortical regions are involved in these processes, but instead, how they are involved. The book is also organized around two basic concepts: (1) the functional neuroanatomy of the basal ganglia and the cerebellum; and (2) how this relates to behavior and neuropsychological testing. Cognitive neuroscience is entering a new era as we recognize the roles of subcortical structures in the modulation of cognition. The fields of neuropsychology, cognitive psychology, neuropsychiatry, and neurology are all developing in the direction of understanding the roles of subcortical structures in behavior. This book is informative while defining the need and direction for new paradigms and methodologies for neuropsychological assessment.

The Oxford Handbook of Neurolinguistics

Author : Greig I. de Zubicaray
Publisher : Oxford University Press
Page : 672 pages
File Size : 42,23 MB
Release : 2019-03-01
Category : Language Arts & Disciplines
ISBN : 0190914866

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Neurolinguistics is a young and highly interdisciplinary field, with influences from psycholinguistics, psychology, aphasiology, and (cognitive) neuroscience, as well as other fields. Neurolinguistics, like psycholinguistics, covers aspects of language processing; but unlike psycholinguistics, it draws on data from patients with damage to language processing capacities, or the use of modern neuroimaging technologies such as fMRI, TMS, or both. The burgeoning interest in neurolinguistics reflects that an understanding of the neural bases of this data can inform more biologically plausible models of the human capacity for language. The Oxford Handbook of Neurolinguistics provides concise overviews of this rapidly-growing field, and engages a broad audience with an interest in the neurobiology of language. The chapters do not attempt to provide exhaustive coverage, but rather present discussions of prominent questions posed by given topics. The volume opens with essential methodological chapters: Section I, Methods, covers the key techniques and technologies used to study the neurobiology of language today, with chapters structured along the basic divisions of the field. Section II addresses the neurobiology of language acquisition during healthy development and in response to challenges presented by congenital and acquired conditions. Section III covers the many facets of our articulate brain, or speech-language pathology, and the capacity for language production-written, spoken, and signed. Questions regarding how the brain comprehends meaning, including emotions at word and discourse levels, are addressed in Section IV. Finally, Section V reaches into broader territory, characterizing and contextualizing the neurobiology of language with respect to more fundamental neuroanatomical mechanisms and general cognitive domains.

Subcortical Functions in Language and Memory

Author : Bruce A. Crosson
Publisher : Guilford Press
Page : 392 pages
File Size : 44,2 MB
Release : 1992-02-01
Category : Psychology
ISBN : 9780898627909

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How do the thalamus, basal ganglia, and basal forebrain participate in language and memory? Are these anatomic entities involved in regulation of cortical activity, complex information processing, transfer of information between cortical units, motivation, or in other functions? This volume is the first single-authored volume devoted to understanding how deep brain structures participate in language and memory. Addressing a relatively new area of research, the book is unique in two ways. First, it comprehensively covers both language and memory not only with extensive literature reviews, but also with examinations of the anatomy of the structures involved and discussions of theory in light of empirical data. Second, the book takes a systems approach to the topics. In order to produce and understand language or to record and retrieve memories, different parts of the brain must operate as integrated systems. As subcortical structures are parts of these systems, this book endeavors to understand how these phylogenetically older structures contribute to systems responsible for communication and mnestic functions. Designed to facilitate this end, each of the book's sections follows a neuroanatomy--empirical data--theory format. Part I concentrates on the participation (or nonparticipation) of various subcortical structures in language. Rather than attempt to arrive at definitive conclusions, these chapters explore the possibilities suggested by the currently available data. Following a description of the neuroanatomy and a discussion of the data concerning the thalamus and basal ganglia, attention is paid to theories regarding the participation of these structures in language. Part II addresses the thalamus, other diencephalic structures, the basal forebrain, and the basal ganglia regarding their possible roles in memory. The connections between these structures are addressed, as is the relationship between current data on the participation of subcortical structures in memory and current neuropsychological assumptions about memory. The extensive literature on memory in alcoholic Korsakoff's syndrome and Huntington's disease is culled for insights into what memory processes are subserved by subcortical structures, and memory theory is examined in light of what the subcortical literature reveals about memory. Paving the way for future research that holds the promise of a greater flexibility and complexity than now exists with purely cortical models, this volume will interest clinical and experimental neuropsychologists, cognitive psychologists, behavioral neurologists, speech/language pathologists, and psychiatrists with an interest in behavioral neurology. It also serves as a text for upper level graduate courses covering subcortical functions in cognition, neural systems, and advanced human neuropsychology.

Discovering the Brain

Author : National Academy of Sciences
Publisher : National Academies Press
Page : 195 pages
File Size : 38,57 MB
Release : 1992-01-01
Category : Medical
ISBN : 0309045290

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The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

Exploring the Thalamus and Its Role in Cortical Function

Author : S. Murray Sherman
Publisher : MIT Press (MA)
Page : 0 pages
File Size : 33,5 MB
Release : 2006
Category : Higher nervous activity
ISBN : 9780262195324

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The thalamus plays a critical role in perceptual processing, but many questions remain about what thalamic activities contribute to sensory and motor functions. In this book, two pioneers in research on the thalamus examine the close two-way relationships between thalamus and cerebral cortex and look at the distinctive functions of the links between the thalamus and the rest of the brain. Countering the dominant "corticocentric" approach to understanding the cerebral cortex—which does not recognize that all neocortical areas receive important inputs from the thalamus and send outputs to lower motor centers—S. Murray Sherman and R. W. Guillery argue for a reappraisal of the way we think about the cortex and its interactions with the rest of the brain. The book defines some of the functional categories critical to understanding thalamic functions, including the distinctions between drivers (pathways that carry messages to the cortex) and modulators (which can change the pattern of transmission) and between first-order and higher-order thalamic relays—the former receiving ascending drivers and the latter receiving cortical drivers. This second edition further develops these distinctions with expanded emphasis throughout the book on the role of the thalamus in cortical function. An important new chapter suggests a structural basis for linking perception and action, supplying supporting evidence for a link often overlooked in current views of perceptual processing.

The Linguistic Cerebellum

Author : Peter Mariën
Publisher : Academic Press
Page : 446 pages
File Size : 28,29 MB
Release : 2015-09-07
Category : Medical
ISBN : 0128017856

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The Linguistic Cerebellum provides a comprehensive analysis of this unique part of the brain that has the most number of neurons, each operating in distinct networks to perform diverse functions. This book outlines how those distinct networks operate in relation to non-motor language skills. Coverage includes cerebellar anatomy and function in relation to speech perception, speech planning, verbal fluency, grammar processing, and reading and writing, along with a discussion of language disorders. Discusses the neurobiology of cerebellar language functions, encompassing both normal language function and language disorders Includes speech perception, processing, and planning Contains cerebellar function in reading and writing Explores how language networks give insight to function elsewhere in the brain

The Contribution of the Hippocampus to Language Processing

Author : Saleh Alamri
Publisher :
Page : 218 pages
File Size : 27,88 MB
Release : 2017
Category :
ISBN :

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Humans display distinct unlimited capacity to produce expressions in language and use them flexibly in language processing. This characteristic of human language allows speakers to use novel, flexible, and complex structures during communication. Neurobiologically, however, it is not fully understood how the rapid process of language production and language comprehension occurs, including word generation, interpretations and common representations that facilitate the process of real-time language processing. The classical theories and approaches have limited the language network to perisylvian cortical regions, namely the Broca's and Wernicke's areas. This thesis proposes that the language network goes beyond the cortical regions indicated by traditional views. In doing so, this thesis puts forward a hypothesis that subcortical structures are not only fundamental to memory but also to language, in which online language processing receives a major contribution from the hippocampal declarative memory, which allows speakers and listeners to use language flexibly. The mechanism of such a contribution by the hippocampal declarative memory system during online language processing is via relational binding in which hippocampal declarative memory rapidly retrieves a network of relative, stored information to serve in the particular context. To support the hypothesis of hippocampal implications in language processing, several pathologies that affect the hippocampus have been reviewed, including Alzheimer's disease, Down syndrome, Williams' syndrome, schizophrenia, depression and bipolar disorder. The review evaluated hippocampal neurobiological alterations in each pathology, and determined cognitive and language profiles. Findings from previous pathologies indicate that the hippocampus affects language at two levels. First, in the general delay in language acquisition and other cognitive aspects, and second, in the disturbed use of language during online communication; short lag interaction is seen to occur when the hippocampal formation is lesioned. It appears that hippocampal lesions suppress the flexible use of stored information within certain contexts in communication, as it does in flexible navigation in animal models. This thesis concludes that the hippocampus is a multi-cognitive operator that is implicated in several cognitive areas including the flexible use of language during real-time processing, and therefore it should be taken into account in the language network in the human brain.

Subcortical Dementia

Author : Jeffrey L. Cummings
Publisher : Oxford University Press, USA
Page : 296 pages
File Size : 28,9 MB
Release : 1990
Category : Language Arts & Disciplines
ISBN :

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This is the first book devoted to subcortical dementia. It brings together the contributions of neurologists, neuropsychologists, neurochemists, and neuroanatomists to provide a comprehensive description of the dementia syndromes associated with subcortical dysfunction. The behavioral and neuropsychological alterations observed in multiple subcortical strokes, Parkinson's disease, Huntington's disease, and other disorders affecting the deep hemispheric brain are presented. The profiles of subcortical dementia recently identified in the AIDS dementia complex and multiple sclerosis are also discussed. The contrasting neuropsychological profile of subcortical dementias and cortical disorders such as Alzheimer's disease are summarized, and clinically useful means of distinguishing among dementing disorders are emphasized. The book provides practical information that will help clinicians evaluate and treat the many disorders that manifest intellectual impairment in association with subcortical disease. It also synthesizes information from a variety of clinical and basic scientific disciplines to enhance understanding of the role of subcortical structures in human cognition.

The Neurobiology of Learning

Author : John H. Schumann
Publisher : Routledge
Page : 237 pages
File Size : 24,35 MB
Release : 2014-04-04
Category : Education
ISBN : 1135619514

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This book constitutes a timely contribution to the existing literature by presenting a relatively comprehensive, neurobiological account of certain aspects of second language acquisition. It represents the collaborative efforts of members of the Neurobiology of Language Research Group in the Applied Linguistics and TESL Department at UCLA. Members of the group are trained in neurobiology and then use this knowledge to develop biological accounts of various aspects of applied linguistics. The volume avoids the corticocentric bias that characterizes many brain-language publications--both cortical and subcortical structures receive their appropriate attention. In addition, it demonstrates that enough is presently known about the brain to inform our conceptualizations of how humans acquire second languages, thus, it provides a refreshingly novel, highly integrative contribution to the (second) language acquisition literature. The goal of the research program was based on the need to draw more links between the neurobiological mechanisms and second language acquisition. As such, the book promotes a neurobiology of language that starts with the brain and moves to behavior. The fundamental insights presented should guide second language acquisition researchers for years to come.