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Technological Advances in the Treatment of Type 1 Diabetes

Author : D. Bruttomesso
Publisher : Karger Medical and Scientific Publishers
Page : 274 pages
File Size : 10,72 MB
Release : 2014-11-17
Category : Medical
ISBN : 331802337X

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The current epidemic of diabetes, obesity and related disorders is a driving force in the development of new technologies. Technological advances offer great new opportunities for the treatment of these chronic diseases. This review presents an update of developments that promise to revolutionize the treatment of diabetes. It examines hospital and outpatient care, intensive insulin therapy, blood glucose monitoring and innovative steps towards the construction of an artificial pancreas. Providing a comprehensive overview on the latest advances, this volume of Frontiers in Diabetes will be of particular interest to all healthcare providers involved in the daily management of patients with diabetes or related diseases.

Diabetes Digital Health

Author : David C. Klonoff
Publisher : Elsevier
Page : 311 pages
File Size : 15,15 MB
Release : 2020-04-04
Category : Medical
ISBN : 0128174862

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Diabetes Digital Health brings together the multifaceted information surrounding the science of digital health from an academic, regulatory, industrial, investment and cybersecurity perspective. Clinicians and researchers who are developing and evaluating mobile apps for diabetes patients will find this essential reading, as will industry people whose companies are developing mobile apps and sensors. Provides valuable information for clinicians, researchers and industry about the design and evaluation of patient-facing diabetes adherence technologies Highlights cutting-edge topics that are presented and discussed at the Digital Diabetes Congress

Personalized Predictive Modeling in Type 1 Diabetes

Author : Eleni I. Georga
Publisher : Academic Press
Page : 253 pages
File Size : 42,50 MB
Release : 2017-12-11
Category : Computers
ISBN : 0128051469

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Personalized Predictive Modeling in Diabetes features state-of-the-art methodologies and algorithmic approaches which have been applied to predictive modeling of glucose concentration, ranging from simple autoregressive models of the CGM time series to multivariate nonlinear regression techniques of machine learning. Developments in the field have been analyzed with respect to: (i) feature set (univariate or multivariate), (ii) regression technique (linear or non-linear), (iii) learning mechanism (batch or sequential), (iv) development and testing procedure and (v) scaling properties. In addition, simulation models of meal-derived glucose absorption and insulin dynamics and kinetics are covered, as an integral part of glucose predictive models. This book will help engineers and clinicians to: select a regression technique which can capture both linear and non-linear dynamics in glucose metabolism in diabetes, and which exhibits good generalization performance under stationary and non-stationary conditions; ensure the scalability of the optimization algorithm (learning mechanism) with respect to the size of the dataset, provided that multiple days of patient monitoring are needed to obtain a reliable predictive model; select a features set which efficiently represents both spatial and temporal dependencies between the input variables and the glucose concentration; select simulation models of subcutaneous insulin absorption and meal absorption; identify an appropriate validation procedure, and identify realistic performance measures. Describes fundamentals of modeling techniques as applied to glucose control Covers model selection process and model validation Offers computer code on a companion website to show implementation of models and algorithms Features the latest developments in the field of diabetes predictive modeling

The Discovery of Insulin

Author : Michael Bliss
Publisher : University of Toronto Press
Page : 320 pages
File Size : 44,82 MB
Release : 2017-06-22
Category : Medical
ISBN : 1487516746

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The discovery of insulin at the University of Toronto in 1921-22 was one of the most dramatic events in the history of the treatment of disease. Insulin was a wonder-drug with ability to bring patients back from the very brink of death, and it was no surprise that in 1923 the Nobel Prize for Medicine was awarded to its discoverers, the Canadian research team of Banting, Best, Collip, and Macleod. In this engaging and award-winning account, historian Michael Bliss recounts the fascinating story behind the discovery of insulin – a story as much filled with fiery confrontation and intense competition as medical dedication and scientific genius. Originally published in 1982 and updated in 1996, The Discovery of Insulin has won the City of Toronto Book Award, the Jason Hannah Medal of the Royal Society of Canada, and the William H. Welch Medal of the American Association for the History of Medicine.

Oral Delivery of Insulin

Author : T.A. Sonia
Publisher : Elsevier
Page : 361 pages
File Size : 17,17 MB
Release : 2014-12-11
Category : Medical
ISBN : 1908818689

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Diabetes Mellitus, a syndrome of disordered metabolism, characterised by abnormal elevation in blood glucose level, has become a life-threatening condition for many people. Current means of therapy for Diabetes Mellitus do not mimic the normal physiological pattern of insulin release. Oral delivery is the preferred route of administration due to its non-invasive nature. Oral delivery of insulin presents an overview of Diabetes Mellitus, and discusses the strategies and techniques adopted for oral delivery of insulin. This title begins with an introductory chapter on symptoms, complications and therapy for Diabetes Mellitus. Subsequent chapters cover the various routes for administering insulin; the challenges and strategies of oral delivery; experimental techniques in the development of an oral insulin carrier; lipids; inorganic nanoparticles and polymers in oral insulin delivery; and a summary and presentation of future perspectives on oral delivery of insulin. Presents an overview of Diabetes Mellitus Includes a discussion of various strategies and techniques adopted for oral delivery of insulin Presents an update of research in the field

Recent Advances in Diabetes

Author : Rajeev Chawla
Publisher : Jaypee Brothers Medical Publishers
Page : 158 pages
File Size : 28,88 MB
Release : 2018-11-20
Category : Medical
ISBN : 9386261677

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Stem Cells – From Hype to Real Hope

Author : Khawaja Husnain Haider
Publisher : Walter de Gruyter GmbH & Co KG
Page : 340 pages
File Size : 46,18 MB
Release : 2018-12-17
Category : Medical
ISBN : 3110586916

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This book is a compilation of the bench experience of leading experts from various research labs involved in the cutting edge area of research. The authors describe the use of stem cells both as part of the combinatorial therapeutic intervention approach and as tools (disease model) during drug development, highlighting the shift from a conventional symptomatic treatment strategy to addressing the root cause of the disease process. The book is a continuum of the previously published book entitled "Stem Cells: from Drug to Drug Discovery" which was published in 2017.

Medical Management of Type 1 Diabetes

Author : Cecilia C. Low Wang
Publisher :
Page : 0 pages
File Size : 16,21 MB
Release : 2016-11-15
Category : Diabetes
ISBN : 9781580406307

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Type 1 diabetes, formerly known as juvenile diabetes, is a complex disorder that requires a great deal of patient-guided self-care. In recent years, advances in diabetes treatment have dramatically shifted potential outcomes in the favor of the patient with diabetes. The challenge for health care professionals is to realize this potential through an individualized, flexible, and responsive treatment plan for patients with type 1 diabetes. Now in its seventh edition, Medical Management of Type 1 Diabetes offers health care providers the newest information and guidelines for the treatment of type 1 diabetes. Built on the foundation of multiple daily insulin injections and insulin pump therapy, this book guides health care providers in helping their patients continually strive for optimal blood glucose control. This new edition focuses on the latest molecular advances, new treatment methods, recent clinical trials, and the American Diabetes Association's Standards of Care. Key topics also include new insulins and administration protocols, advanced carbohydrate counting, and emphasis on continuing patient education. Individual sections address all of the topics in managing type 1 diabetes, including diagnosis and classification/pathogenesis, diabetes standards and education, tools of therapy, special situations, psychosocial factors affecting adherence, quality of life, and well-being and complications. Medical Management of Type 1 Diabetes is an essential addition to any clinician's library for the treatment and understanding of type 1 diabetes.

Diabetes Technology

Author : Boris Draznin
Publisher : American Diabetes Association
Page : 476 pages
File Size : 36,87 MB
Release : 2019-06-17
Category : Medical
ISBN : 1580407072

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We live in a century of technological revolution and the birth of artificial intelligence. Like every other sphere of our life, diabetes-related technology is moving forward with lightning speed. New and improved insulin administration devices, increased capacity for monitoring one’s blood glucose levels, and the ability to communicate directly with the device supplying insulin as well as with the patient and his/her healthcare provider have changed diabetes therapy forever. The problem is that diabetes-related technology is moving ahead much faster than physicians and other healthcare professionals can incorporate these advances into our practices. Diabetes Technology will consist of three parts: Part I addresses the clinical science of diabetes pumps, continuous glucose monitoring and communication technology with numerous practical aspects. Part III offers personal stories of healthcare providers who treat their own diabetes with modern diabetes technology. In particular, they will address how and why they decided to use this technology and the positive and negative aspects of their decision.