[PDF] Statistical Method In Biological Assay Dj Finney eBook

Author : Z. Govindarajulu
Publisher : Karger Medical and Scientific Publishers
Page : 249 pages
File Size : 14,9 MB
Release : 2001
Category : Science
ISBN : 3805571194

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In the face of the ever-increasing importance of statistical methods in medical research and practice, the first edition of this publication has provided a sound and deep understanding of statistical methods in bioassay to many students and researchers. In addition to the profound presentation of statistical methods of the first edition, here the reader will find new material stemming from the recent statistical literature as well as data reflecting modern trends in general applied statistical research. Examples are discussions on design and planning, e.g. choices of dose levels, and additional section in the chapter on Bayes methods, and a new chapter on sequential estimation for the logistic model. The book will be a valuable source of information to students in the experimental area of statistical aspects of biological assay, professional statisticians with an interest in research in this topic, teachers in statistics and biology, and investigators in the biological and medical sciences who use bioassay in their work.

Author : Charles Ralph Buncher
Publisher : CRC Press
Page : 606 pages
File Size : 30,5 MB
Release : 1993-11-17
Category : Mathematics
ISBN : 9780824790738

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This rewritten and updated second edition provides comprehensive information on the wide-ranging applications of statistics in the pharmacological field. Focusing on practical aspects, it sets out to bridge the gap between industry and academia.;Reflecting the changes that have taken place since publication of the first edition, this volume covers new topics such as: cancer clinical trials, clinical trials of AIDS patients and animal tumorigenicity studies; the development of antiepileptic drugs; the role of epidemiology in postmarketing trials and adverse drug experience; computer-assisted new drug application (CANDA) submissions; contract research organizations; interim analysis in clinical trials; and room-temperature tests for the stability of drugs.;This work is intended as: a reference for statisticians, biostatisticians, pharmacologists, administrators, managers, and scientists in the pharmaceutical industry; and a text for graduate students taking courses in applied statistics or pharmaceutical statistics.

Author : David J. Finney
Publisher : Charles Griffin Book
Page : 522 pages
File Size : 45,41 MB
Release : 1987
Category : Biological assay.
ISBN : 9780195205671

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A standard work for 30 years, this book emphasizes experimental design and the practice of statistical estimation, making it especially valuable for those working as consultants in research and technology. The author describes the central statistical procedures for radioimmunoassay, and presents new ideas on the combination of bioassay results. He describes routine assay computations and illustrates recently developed programs for quantitative and quantal responses.

Author : Michael C. Newman
Publisher : CRC Press
Page : 452 pages
File Size : 29,33 MB
Release : 1994-12-21
Category : Science
ISBN : 9780873716222

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This book provides a quantitative treatment of the science of ecotoxicology. The first chapters consider fundamental concepts and definitions essential to understanding the fate and effects of toxicants at various levels of ecological organization as covered in the remaining chapters. Scientific ecotoxicology and associated topics are defined. The historical perspective, rationale, and characteristics are outlined for the strong inferential and quantitative approach advocated in this book. The general measurement process is discussed, and methodologies for defining and controlling variance, which could otherwise exclude valid conclusions regarding ecotoxicological endeavors, are considered. Ecotoxicological concepts at increasing levels of ecological organization are discussed in the second part of the book. Quantitative methods used to measure toxicant effects are outlined in this section. The final chapter summarizes the book with a brief discussion of ecotoxicological assessment. Numerous figures and tables accompany text, with many statistical tables found in the appendix for quick reference. Although the book primarily focuses on aquatic systems, with appropriate modification the concepts and methods can be applied to terrestrial systems.

Author : Uchenna Petronilla Ogoke
Publisher : IPS Intelligentsia Publishing Services
Page : 72 pages
File Size : 16,95 MB
Release : 2021-08-21
Category : Medical
ISBN : 9789912730

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Statistical Theory and Analysis in Bioassay is a seven chapter monograph tailored essentially to meet the needs of graduate students, practitioners and researchers in the fields of medicine, pharmacology, biosciences/life sciences and related fields that employs the tools of biostatistics in bioassays and analysis. In this wise, we have taken time to discuss in details relevant topics; principles, methods and applications. Practice exercises are also included where necessary. The earlier chapters give background information, definition of terms, purpose, types, structure and relative potency in bioassay. An important theorem, Fieller’s theorem is proved in details with illustrative examples. The last two chapters are on dose-response relationship, fitting in parallelline assays and estimation. We are convinced that this monograph will meet the expectations of the readers while constructive criticisms that will improve another edition will be appreciated.