[PDF] Recent Advances In Scar Biology eBook

Author : Rei Ogawa
Publisher : MDPI
Page : 203 pages
File Size : 41,45 MB
Release : 2019-01-29
Category : Biology (General)
ISBN : 303897398X

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This book is a printed edition of the Special Issue "Recent Advances in Scar Biology" that was published in IJMS

Author : Luc Téot
Publisher : Springer Nature
Page : 553 pages
File Size : 26,37 MB
Release : 2020-12-07
Category : Medical
ISBN : 3030447669

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This text book is open access under a CC BY 4.0 license. Written by a group of international experts in the field and the result of over ten years of collaboration, it allows students and readers to gain to gain a detailed understanding of scar and wound treatment – a topic still dispersed among various disciplines. The content is divided into three parts for easy reference. The first part focuses on the fundamentals of scar management, including assessment and evaluation procedures, classification, tools for accurate measurement of all scar-related elements (volume density, color, vascularization), descriptions of the different evaluation scales. It also features chapters on the best practices in electronic-file storage for clinical reevaluation and telemedicine procedures for safe remote evaluation. The second section offers a comprehensive review of treatment and evidence-based technologies, presenting a consensus of the various available guidelines (silicone, surgery, chemical injections, mechanical tools for scar stabilization, lasers). The third part evaluates the full range of emerging technologies offered to physicians as alternative or complementary solutions for wound healing (mechanical, chemical, anti-proliferation). Textbook on Scar Management will appeal to trainees, fellows, residents and physicians dealing with scar management in plastic surgery, dermatology, surgery and oncology, as well as to nurses and general practitioners

Author : Berna Aksoy
Publisher :
Page : 464 pages
File Size : 25,11 MB
Release : 2019-07-25
Category :
ISBN : 9781536156577

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Any cutaneous insult results in wound healing and wound healing results in formation of a scar. Human cutaneous scars represent a very important problem in clinical practice. Human cutaneous scars cause both cosmetic and medical problems in people who have them. There are various types of human cutaneous scars: physiologic normotrophic scars, atrophic scars, and proliferative scars. Additionally, there are scar complications that physicians must deal with. Scar complications include unstable scars, contractures and even development of malignancy at worst. Treatment of scars is also challenging especially in case of development of abnormal scars. Human cutaneous scars have various aspects of interest such as biology, clinical significance, patient perspective, prevention, and treatment. There are various preclinical models for studying them. Scarless healing is another item of interest that is observed in fetal wound healing and in some animals. There are various studies specifically examining the biology and the treatment of proliferative scars. The cutaneous scars are very common so every physician will face a cutaneous scar-related problem in his/her medical practice. The significance is indicated by the frequency of burn injury and traffic accidents and by the importance of incision scars for any surgeon. The editors of this book have enormous experience in the clinical management of human cutaneous scars. The editors also studied the biology of abnormal scarring by developing new animal models. The editors also have performed clinical studies to increase therapeutic options for the treatment of abnormal scars. In this hardcover book, the aim is to examine human cutaneous scars in every aspect: historical aspects, clinical significance, biology, laboratory and animal models, histopathology, scarless healing, scar complications, and treatment. In this book, all the available treatment methods are examined in detail.

Author : Andrew C. Krakowski
Publisher : Lippincott Williams & Wilkins
Page : 928 pages
File Size : 20,73 MB
Release : 2017-02-08
Category : Medical
ISBN : 1496384814

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Apply cutting-edge expertise to manage your patients’ scarring issues! Scarring and fibrosis affect millions of people worldwide, and can be devastating both physically and psychologically, whether they result from major trauma such as burns or common conditions such as acne. Put today’s most advanced clinical approaches to work for your patients with The Scar Book: Formation, Mitigation, Rehabilitation, and Prevention! A multidisciplinary team of leading world experts presents the state of the art in scar pathophysiology and treatment, breaking down the barriers between medical disciplines to provide unprecedented holistic guidance.

Author : Robert Fitridge
Publisher : University of Adelaide Press
Page : 589 pages
File Size : 35,31 MB
Release : 2011
Category : Medical
ISBN : 1922064009

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New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Author : Institute of Medicine
Publisher : National Academies Press
Page : 457 pages
File Size : 15,59 MB
Release : 2001-08-10
Category : Medical
ISBN : 0309072859

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Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.

Author : Mohammad Albanna
Publisher : Academic Press
Page : 468 pages
File Size : 16,47 MB
Release : 2016-01-14
Category : Technology & Engineering
ISBN : 012801797X

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The skin is the largest human organ system. Loss of skin integrity due to injury or illness results in a substantial physiologic imbalance and ultimately in severe disability or death. From burn victims to surgical scars and plastic surgery, the therapies resulting from skin tissue engineering and regenerative medicine are important to a broad spectrum of patients. Skin Tissue Engineering and Regenerative Medicine provides a translational link for biomedical researchers across fields to understand the inter-disciplinary approaches which expanded available therapies for patients and additional research collaboration. This work expands on the primary literature on the state of the art of cell therapies and biomaterials to review the most widely used surgical therapies for the specific clinical scenarios. Explores cellular and molecular processes of wound healing, scar formation, and dermal repair Includes examples of animal models for wound healing and translation to the clinical world Presents the current state of, and clinical opportunities for, extracellular matrices, natural biomaterials, synthetic biomaterials, biologic skin substitutes, and adult and fetal stem and skin cells for skin regenerative therapies and wound management Discusses new innovative approaches for wound healing including skin bioprinting and directed cellular therapies

Author : Niti Khunger
Publisher : Elsevier Health Sciences
Page : 136 pages
File Size : 34,67 MB
Release : 2013-07-12
Category : Medical
ISBN : 8131231712

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A number of scar revision techniques can be utilized to treat specific types of scars, in combination with each other or with adjunctive therapies to achieve optimal results. Pathological conditions like hypertrophic scars and keloids are still challenging. Though a number of therapies exist to treat keloids, such as intralesional steroids and anti-metabolites, cryosurgery, to name a few, none are definitive in treatment. Understanding the molecular basis of keloids may lead to development of new therapies. Striae, also known as ‘stretch marks’, are extremely common, disfiguring and a real challenge to treat. Management of striae is a neglected field of research. Except for topical retinoids, the efficacy satisfactorily. Current treatment options include chemical peels, lasers and collagen induction therapy, with a tendency towards active intervention. However, studies are necessary to determine treatment strategies which produce results that are effective with minimal adverse effects. Post-acne scarring is one of the most common causes of facial scars, causing considerable cosmetic disability. Acne is a common skin disorder, unfortunately affecting a large number of teenagers. Usually patients have a combination of different types of scars; hence no single modality is useful. A combination of procedures is generally required for a satisfactory cosmetic outcome. The use of fractional lasers is gaining importance, as it is a minimally invasive procedure as compared to aggressive resurfacing procedures of the past. Collagen induction therapy is another promising technique. Today, patients are also getting up-to-date information about the various modalities available for scar treatment through media, such as magazines, advertisements and internet. However, exaggerated advertisements and information from nonprofessional sources, particularly with regard to lasers can influence patient expectations and result in unrealistic expectations. Patients need to understand that deep scars cannot be eliminated fully and can only be improved. They usually have high expectations from procedural techniques. Proper counseling is extremely important for a happy and satisfactory outcome. Current innovations and techniques in scar prevention and management and increasing use of minimally invasive surgeries are paving the way toward smoother, less noticeable scars. Every surgeon practicing aesthetics should be well versed with modalities of scar management and this is the aim of this clinical update.