[PDF] Multiple Risk Factors In Cardiovascular Disease eBook

Author : Antonio M. Gotto Jr.
Publisher : Springer Science & Business Media
Page : 370 pages
File Size : 36,55 MB
Release : 2012-12-06
Category : Medical
ISBN : 9401150222

GET BOOK

This volume is a collection of the most significant contributions to the 4th International Symposium on MULTIPLE RISK FACTORS IN CARDIOVASCULAR DISEASE: STRATEGIES OF PREVENTION OF CORONARY HEART DISEASE, CARDIAC F AlLURE, AND STROKE held in Washington, D. C. in April 1997. The meeting focused on the risk factors for cardiovascular disease and their interactions. The need for this symposium is based on the epidemiological, clinical, and biological evidence that individuals from industrialized countries often possess two or more risk factors which synergistically increase the global risk profile. This has become more evident in recent years with the increase in life expectancy of populations in the industrialized countries. The evidence that a combination of risk factors confers a very high risk of developing cardiovascular diseases, is of pivotal interest in the process of detection of patients who will benefit the most from pharmacological treatment. Many recent epidemiological data identifying the intrinsic and environmental factors contributing to the development of atherosclerosis are discussed. These results, in parallel with basic and clinical research, underline atherosclerosis as a complex and multifactorial process involving the influences of lipids, including lipoprotein subfractions, blood pressure rheologic forces, carbohydrate tolerance, and thrombogenic factors, including fibrinogen, tissue factor, PAl-I, and homocysteine. Furthennore, the risk associated with anyone of these risk factors varies widely depending on the level of the associated atherogenic risk factors. Hyper cholesterolemia and hypertriglyceridemia, for instance, are more common than would be expected by chance among hypertensive patients.

Author : Antonio M. Gotto Jr.
Publisher : Springer Science & Business Media
Page : 357 pages
File Size : 34,93 MB
Release : 2013-06-29
Category : Medical
ISBN : 940112700X

GET BOOK

This book includes the most significant contributions of the First International Symposium on "Multiple risk factors in cardiovascular disease", chaired by Professors A. V. Chobanian (Boston), A. M. Gotto Jr. (Houston), c. Lenfant (Bethesda), R. Paoletti and A. Zanchetti (Milan), held in Washington DC, 10-12 December 1990, which focused on the risk factors for cardiovascular disease and their interactions. The need for this symposium is based on the epidemiological evidence that individuals from industrialized countries often possess two or more risk factors which synergically increase the global risk profile. The evidence that isolated vascular risk factors are not commonly found in high risk patients but more often a combination of risk factors are detected, is highlighted. Many recent epidemiological data identifying the intrinsic and environ mental factors contributing to the development of atherosclerosis are discussed. These results, in parallel to basic and clinical research, underline how atherosclerosis is a complex and multifac torial process involving the influences of lipid deposition, blood pressure, rheologic forces, carbohydrate tolerance, and thrombogenic factors (fibrinogen and platelets). Atherosclerosis is markedly accelerated by other risk factors, more so in the presence of concomitant hypercholes terolemia, hypertension, diabetes, upper body obesity. Furthermore, the risk associated with anyone of these risk factors varies widely depending on level of the associated atherogenic risk factors.

Author : Dorairaj Prabhakaran
Publisher : World Bank Publications
Page : 948 pages
File Size : 23,91 MB
Release : 2017-11-17
Category : Medical
ISBN : 1464805202

GET BOOK

Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.

Author : Antonio M. Gotto
Publisher :
Page : 478 pages
File Size : 25,51 MB
Release : 1995
Category : Medical
ISBN :

GET BOOK

Patients with two or more risk factors have a very high risk of developing cardiovascular disease. It follows that the strategy for the intervention of multiple risk factors is in fact of paramount relevance in detecting patients at high risk of cardiovascular disease requiring therapeutic intervention. The text also discusses risk factors from the point of view of biochemists and pharmacologists by addressing the mechanisms underlying the onset of hypertension, hyperlipoproteinaemia, hypercoagulability and the possibility of therapeutic intervention.

Author : Naranjan S. Dhalla
Publisher : Springer
Page : 648 pages
File Size : 31,49 MB
Release : 2012-10-31
Category : Medical
ISBN : 9781461350842

GET BOOK

Pathophysiology of Cardiovascular Disease has been divided into four sections that focus on heart dysfunction and its associated characteristics (hypertrophy, cardiomyopathy and failure); vascular dysfunction and disease; ischemic heart disease; and novel therapeutic interventions. This volume is a compendium of different approaches to understanding cardiovascular disease and identifying the proteins, pathways and processes that impact it.

Author : Nikolaos Papageorgiou
Publisher : Academic Press
Page : 254 pages
File Size : 36,89 MB
Release : 2016-08-05
Category : Science
ISBN : 0128033134

GET BOOK

Cardiovascular Diseases: Genetic Susceptibility, Environmental Factors and Their Interaction covers the special heritability characteristics and identifying genetic and environmental contributions to cardiovascular health. This important reference provides an overview of the genetic basis of cardiovascular disease and its risk factors. Included are important topics, ranging from lifestyle choices, risk factors, and exposure, to pollutants and chemicals. Also covered are the influences of Mendelian traits and familial aggregation and the interactions and interrelationships between genetics and environmental factors which, when compared, provide a sound understanding of the interplay between inherited and acquired risk factors. The book provides a much needed reference for this rapidly growing field of study. By combining the latest research within the structured chapters of this reference, a better understanding of genetic and environmental contribution to cardiovascular disease is found, helping to substantiate further investigations in the field and design prevention and treatment strategies. Provides an overview of the genetic basis of cardiovascular disease and its risk factors Reviews several large population-based studies which indicate that exposure to several environmental factors may increase CVD morbidity and mortality, exploring the plausibility of this association by data from animal studies Reflects on future studies to help understanding the role of genes and environmental factors in the development and progression of cardiovascular disease

Author :
Publisher :
Page : 0 pages
File Size : 35,41 MB
Release : 2001
Category :
ISBN :

GET BOOK

Despite the decrease in coronary heart disease mortality over the past 30 years, coronary heart disease (CHD) continues to reign as the leading cause of death in men and women. Cardiovascular disease, including CHD, kills nearly 500,000 American women each year and black women generally have a higher prevalence of CHD risk factors and a higher death rate at a younger age than white women (Haan, 1996). Risk factors are highly prevalent in women aged 20-74 years. One third have hypertension, 14 have hypercholesterolemia, % are overweight, and % are sedentary. These factors are more prevalent in women of lower socioeconomic status and lower educational level (Wenger, 1995). In 1995, an estimated 34.3% of women reported having 1 risk factor and 30% of women reported having two or more of the following risk factors for cardiovascular disease: hypertension, high blood cholesterol, diabetes, overweight and smoking. The prevalence of two or more risk factors increased with age, decreased with educational level and was higher among black women. The percentage of women with two or more risk factors was significantly higher than estimates from 1992 (Greenlund, et al., 1998).

Author : Institute of Medicine
Publisher : National Academies Press
Page : 200 pages
File Size : 17,21 MB
Release : 2011-08-26
Category : Medical
ISBN : 0309212197

GET BOOK

Chronic diseases are common and costly, yet they are also among the most preventable health problems. Comprehensive and accurate disease surveillance systems are needed to implement successful efforts which will reduce the burden of chronic diseases on the U.S. population. A number of sources of surveillance data-including population surveys, cohort studies, disease registries, administrative health data, and vital statistics-contribute critical information about chronic disease. But no central surveillance system provides the information needed to analyze how chronic disease impacts the U.S. population, to identify public health priorities, or to track the progress of preventive efforts. A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases outlines a conceptual framework for building a national chronic disease surveillance system focused primarily on cardiovascular and chronic lung diseases. This system should be capable of providing data on disparities in incidence and prevalence of the diseases by race, ethnicity, socioeconomic status, and geographic region, along with data on disease risk factors, clinical care delivery, and functional health outcomes. This coordinated surveillance system is needed to integrate and expand existing information across the multiple levels of decision making in order to generate actionable, timely knowledge for a range of stakeholders at the local, state or regional, and national levels. The recommendations presented in A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases focus on data collection, resource allocation, monitoring activities, and implementation. The report also recommends that systems evolve along with new knowledge about emerging risk factors, advancing technologies, and new understanding of the basis for disease. This report will inform decision-making among federal health agencies, especially the Department of Health and Human Services; public health and clinical practitioners; non-governmental organizations; and policy makers, among others.

Author : Jeanne L. Tillotson
Publisher :
Page : 342 pages
File Size : 36,35 MB
Release : 1985
Category : Heart
ISBN :

GET BOOK

Abstract: A monograph for health professionals provides details on a special intervention program for preventing heart disease (MRFIT), covering counseling on how to: adopt and maintain a nutritious fat-controlled diet; avoid weight gain; abstain from cigarette smoking; and comply with drug therapy for hypertension. The health educational materials developed under this program in a 10-year (1972-82) multiple risk factor intervention trial are presented. Included for each risk factor area are: printed educational materials, forms for monitoring the progress of individuals, and an annotated listing of audiovisual materials and their availability.

Author : Roger Detels
Publisher : Oxford University Press
Page : 1717 pages
File Size : 16,33 MB
Release : 2017
Category : Medical
ISBN : 019881013X

GET BOOK

Sixth edition of the hugely successful, internationally recognised textbook on global public health and epidemiology, with 3 volumes comprehensively covering the scope, methods, and practice of the discipline