[PDF] Modeling Hiv Transmission And Aids In The Us eBook

Author : Herbert W. Hethcote
Publisher : Springer Science & Business Media
Page : 243 pages
File Size : 43,30 MB
Release : 2013-03-09
Category : Mathematics
ISBN : 3642514774

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The disease that came to be called acquired immunodeficiency syndrome (AIDS) was first identified in the summer of 1981. By that time, nearly 100,000 persons in the United States may have been infected with human immunodeficiency virus (HIV). By the time the routes of transmission were clearly identified and HIV was established as the cause of AIDS in 1983, over 300,000 people may have been infected. That number has continued to increase, with approximately 1,000,000 Americans believed to be infected in 1991. The epidemic is of great public health concern because HlV is infectious, causes severe morbidity and death in most if not all of those infected, and often occurs in relatively young persons. In addition, the cost of medical care for a person with HIV disease is high, and the medical care needs of HIV-infected persons place a severe burden on the medical care systems in many areas. Understanding and controlling the HIV epidemic is a particularly difficult challenge. The long and variable period between HIV infection and clinical disease makes it difficult both to forecast the future magnitude of the epidemic, which is important for health care planning, and to estimate the number infected in the last several years, which is important for monitoring the current status of the epidemic.

Author : King K. Holmes
Publisher : World Bank Publications
Page : 1027 pages
File Size : 21,69 MB
Release : 2017-11-06
Category : Medical
ISBN : 1464805253

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Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Author : Ron Brookmeyer
Publisher : Oxford University Press
Page : 374 pages
File Size : 39,76 MB
Release : 1994-01-06
Category : Medical
ISBN : 0199748748

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AIDS has appeared in more than 130 countries, and over 100,000 cases of AIDS have been reported in the U.S. alone. More and more, the public will be depending on statisticians to provide answers about the future course of this epidemic. This comprehensive work confronts the problems that are unique to AIDS research and unites them under a single conceptual framework. It focuses on methods for the design and analysis of epidemiologic studies, the natural history of AIDS and the transmission of HIV, methods for tracking and projecting the course of the epidemic, and statistical issues in therapeutic trials. The various methods of monitoring and forecasting this disease receive comprehensive treatment. These methods include back-calculation, which the authors developed; interpretation of survey data on HIV prevalence; mathematical models for HIV transmission; and approaches that combine different types of epidemiological data. Much of this material -- such as a discussion of methods for assessing safety of the blood supply, an evaluation of survey approaches, and methods to project pediatric AIDS incidence -- is not available in any other work.

Author : D. M. Basavarajaiah
Publisher : Springer Nature
Page : 340 pages
File Size : 18,40 MB
Release : 2019-11-29
Category : Medical
ISBN : 9811501513

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This book presents models describing HIV transmission rates at population level, discussing the main statistical methods and analytical interventions. It also assesses the practical applicability of the various modelling techniques, offering readers insights into what methods are available and, more importantly, when they should be used to address HIV transmission at global level. The book includes realistic simulation models fitted to clarify the rate of HIV mother-to-child transmission (HIV MTCT), and substantiates the conclusions that can be drawn as well as the appropriate time for making global-level clinical decisions concerning people living with HIV/AIDS (PLHIVs). Intended for students, academics and researchers, the book offers more than just an introduction to the topic – it also features in-depth, yet easy-to-understand, descriptions of a new mathematical/statistical HIV mother-to-child transmission model, making it a useful resource for clinicians, public health workers and policymakers involved in implementing HIV-prevention programmes at national /global level.

Author : Eric R. Wright
Publisher : Springer
Page : 309 pages
File Size : 37,17 MB
Release : 2016-07-30
Category : Social Science
ISBN : 3319340042

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This book examines the HIV/AIDS epidemic in the United States using the concept of syndemics to contextualize the risk of both well-known, and a few lesser-known, subpopulations that experience disproportionately high rates of HIV and/or AIDS within the United States. Since discovery, HIV/AIDS has exposed a number of social, psychological, and biological aspects of disease transmission. The concept of “syndemics,” or “synergistically interacting epidemics” has emerged as a powerful framework for understanding both the epidemiological patterns and the myriad of problems associated with HIV/AIDS around the world and within the United States. The book considers the disparities in HIV/AIDS in relation to social aspects, risk behavior and critical illness comorbidities. It updates and enhances our understanding of the HIV/AIDS epidemic in the United States and contributes to the expanding literature on the role of syndemics in shaping the public’s health.​

Author : Margaret L. Brandeau
Publisher : Raven Press (ID)
Page : 664 pages
File Size : 26,18 MB
Release : 1994
Category : AIDS (Disease)
ISBN :

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Emerging from the 34th Joint National Meeting of the Operations Research Society of America and The Institute of Management Sciences, held in San Francisco, November 1992, this volume presents AIDS modeling research that can directly or indirectly improve decision making for planning, resource allocation, and public health policy. The volume is divided into four sections: AIDS policy modeling; models for AIDS backcasting and forecasting; modeling infectivity and disease progression; and modeling the social organization of risky behavior. Annotation copyright by Book News, Inc., Portland, OR

Author : W. Y. Tan
Publisher : World Scientific
Page : 610 pages
File Size : 41,30 MB
Release : 2005
Category : Mathematics
ISBN : 9812561390

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- Only book on extensive, deterministic models, statistic models, stochastic models and state space models and statistical methods for HIV epidemic involving IV drug usage and HIV epidemic in homosexual populations. - Provides most recent biological insights into HIV pathogenesis and HIV kinetics at the cellular level, and illustrates how to build up mathematical models based on these biological insights. - Only publication that provides in-depth analysis of HAART treatment protocols and discusses possible improvements to the HAART protocol. The book also provides connection between pharmacokinetics with treatment in HIV-infected individuals.

Author : National Research Council and Institute of Medicine
Publisher : National Academies Press
Page : 352 pages
File Size : 19,81 MB
Release : 1995-09-14
Category : Medical
ISBN : 0309176212

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This volume addresses the interface of two major national problems: the epidemic of HIV-AIDS and the widespread use of illegal injection drugs. Should communities have the option of giving drug users sterile needles or bleach for cleaning needs in order to reduce the spread of HIV? Does needle distribution worsen the drug problem, as opponents of such programs argue? Do they reduce the spread of other serious diseases, such as hepatitis? Do they result in more used needles being carelessly discarded in the community? The panel takes a critical look at the available data on needle exchange and bleach distribution programs, reaches conclusions about their efficacy, and offers concrete recommendations for public policy to reduce the spread of HIV/AIDS. The book includes current knowledge about the epidemiologies of HIV/AIDS and injection drug use; characteristics of needle exchange and bleach distribution programs and views on those programs from diverse community groups; and a discussion of laws designed to control possession of needles, their impact on needle sharing among injection drug users, and their implications for needle exchange programs.