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Hansen Solubility Parameters

Author : Charles M. Hansen
Publisher : CRC Press
Page : 546 pages
File Size : 17,56 MB
Release : 2007-06-15
Category : Science
ISBN : 1420006835

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Hansen solubility parameters (HSPs) are used to predict molecular affinities, solubility, and solubility-related phenomena. Revised and updated throughout, Hansen Solubility Parameters: A User's Handbook, Second Edition features the three Hansen solubility parameters for over 1200 chemicals and correlations for over 400 materials including p

CRC Handbook of Solubility Parameters and Other Cohesion Parameters

Author : Allan F.M. Barton
Publisher : Routledge
Page : 768 pages
File Size : 15,3 MB
Release : 2017-10-19
Category : Science
ISBN : 1351457195

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The CRC Handbook of Solubility Parameters and Other Cohesion Parameters, Second Edition, which includes 17 new sections and 40 new data tables, incorporates information from a vast amount of material published over the last ten years. The volume is based on a bibliography of 2,900 reports, including 1,200 new citations. The detailed, careful construction of the handbook develops the concept of solubility parameters from empirical, thermodynamic, and molecular points of view and demonstrates their application to liquid, gas, solid, and polymer systems.

Green Extraction of Natural Products

Author : Farid Chemat
Publisher : John Wiley & Sons
Page : 384 pages
File Size : 27,62 MB
Release : 2016-03-11
Category : Science
ISBN : 3527676813

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Extraction processes are essential steps in numerous industrial applications from perfume over pharmaceutical to fine chemical industry. Nowadays, there are three key aspects in industrial extraction processes: economy and quality, as well as environmental considerations. This book presents a complete picture of current knowledge on green extraction in terms of innovative processes, original methods, alternative solvents and safe products, and provides the necessary theoretical background as well as industrial application examples and environmental impacts. Each chapter is written by experts in the field and the strong focus on green chemistry throughout the book makes this book a unique reference source. This book is intended to be a first step towards a future cooperation in a new extraction of natural products, built to improve both fundamental and green parameters of the techniques and to increase the amount of extracts obtained from renewable resources with a minimum consumption of energy and solvents, and the maximum safety for operators and the environment.

Nanocoatings: Principles and Practice

Author : Steven Abbott
Publisher : DEStech Publications, Inc
Page : 344 pages
File Size : 43,39 MB
Release : 2013
Category : Technology & Engineering
ISBN : 1605950904

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A practical guide for designing and making commercial coatings to which nanoparticles are added. It shows how to create and recognize a nanocoating formulation with the correct functional properties. It connects formulation and fabrication in ways conducive to the manufacture of marketable nanocoated products.

Handbook of Solubility Data for Pharmaceuticals

Author : Abolghasem Jouyban
Publisher : CRC Press
Page : 554 pages
File Size : 23,68 MB
Release : 2009-08-26
Category : Medical
ISBN : 1439804885

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Aqueous solubility is one of the major challenges in the early stages of drug discovery. One of the most common and effective methods for enhancing solubility is the addition of an organic solvent to the aqueous solution. Along with an introduction to cosolvency models, the Handbook of Solubility Data for Pharmaceuticals provides an extensive datab

Hot-Melt Extrusion

Author : Dennis Douroumis
Publisher : John Wiley & Sons
Page : 404 pages
File Size : 41,36 MB
Release : 2012-04-24
Category : Science
ISBN : 1118307879

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Hot-melt extrusion (HME) - melting a substance and forcing it through an orifice under controlled conditions to form a new material - is an emerging processing technology in the pharmaceutical industry for the preparation of various dosage forms and drug delivery systems, for example granules and sustained release tablets. Hot-Melt Extrusion: Pharmaceutical Applications covers the main instrumentation, operation principles and theoretical background of HME. It then focuses on HME drug delivery systems, dosage forms and clinical studies (including pharmacokinetics and bioavailability) of HME products. Finally, the book includes some recent and novel HME applications, scale -up considerations and regulatory issues. Topics covered include: principles and die design of single screw extrusion twin screw extrusion techniques and practices in the laboratory and on production scale HME developments for the pharmaceutical industry solubility parameters for prediction of drug/polymer miscibility in HME formulations the influence of plasticizers in HME applications of polymethacrylate polymers in HME HME of ethylcellulose, hypromellose, and polyethylene oxide bioadhesion properties of polymeric films produced by HME taste masking using HME clinical studies, bioavailability and pharmacokinetics of HME products injection moulding and HME processing for pharmaceutical materials laminar dispersive & distributive mixing with dissolution and applications to HME technological considerations related to scale-up of HME processes devices and implant systems by HME an FDA perspective on HME product and process understanding improved process understanding and control of an HME process with near-infrared spectroscopy Hot-Melt Extrusion: Pharmaceutical Applications is an essential multidisciplinary guide to the emerging pharmaceutical uses of this processing technology for researchers in academia and industry working in drug formulation and delivery, pharmaceutical engineering and processing, and polymers and materials science. This is the first book from our brand new series Advances in Pharmaceutical Technology. Find out more about the series here.

Adhesion Science

Author : Steven Abbott
Publisher : DEStech Publications, Inc
Page : 319 pages
File Size : 45,99 MB
Release : 2015-06-29
Category : Science
ISBN : 1605951781

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Explains the physics and chemistry of adhesion, surface preparation and testsPresents new strategies for formulating superior strong, weak and pressure-sensitive adhesivesIncludes access to unique electronic apps that enable numerical modeling of adhesives This technical bound book explains the basic principles of adhesion and shows how they are used to formulate and improve adhesives. The volume starts by laying out key physical and chemical concepts underlying adhesion and adhesives, including strong and weak bonds plus pressure-sensitive (PSA) across multiple polymer, metal and ceramic adherends. The ideas are expressed in clear and easily understood mathematical formulas that explain surface properties as well as "good" and "bad" adhesion, with the latter covering multiple types of adhesive failure. In this context, the book presents a detailed explanation of methods to predict, test and formulate adhesives and critically analyzes test results and traditionally accepted rules for adhesive formulation. The eBook version includes online access to a unique set of applied computer programs or "apps" that automate a wide range of adhesive formulas and enable readers to input their own data and numerically model adhesion properties in conjunction with, or prior to, chemical compounding and empirical testing. This volume constitutes a lucid and practical introduction to adhesion and adhesives appropriate for specialists at all levels.

Molecular Gels

Author : Richard G. Weiss
Publisher : Springer Science & Business Media
Page : 969 pages
File Size : 48,14 MB
Release : 2006-06-30
Category : Science
ISBN : 1402036892

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"Molecular Gels: Materials with Self-Assembled Fibrillar Networks" is a comprehensive treatise on gelators, especially low molecular-mass gelators and the properties of their gels. The structures and modes of formation of the self-assembled fibrillar networks (SAFINs) that immobilize the liquid components of the gels are discussed experimentally and theoretically. The spectroscopic, rheological, and structural features of the different classes of low molecular-mass gelators are also presented. Many examples of the application of the principal analytical techniques for investigation of molecular gels (including SANS, SAXS, WAXS, UV-vis absorption, fluorescence and CD spectroscopies, scanning electron, transmission electron and optical microscopies, and molecular modeling) are presented didactically and in-depth, as are several of the theories of the stages of aggregation of individual low molecular-mass gelator molecules leading to SAFINs. Several actual and potential applications of molecular gels in disparate fields (from silicate replication of nanostructures to art conservation) are described. Special emphasis is placed on perspectives for future developments. This book is an invaluable resource for researchers and practitioners either already researching self-assembly and soft matter or new to the area. Those who will find the book useful include chemists, engineers, spectroscopists, physicists, biologists, theoreticians, and materials scientists.

Hansen Solubility Parameters

Author : Charles M. Hansen
Publisher : CRC Press
Page : 224 pages
File Size : 13,79 MB
Release : 1999-09-17
Category : Science
ISBN : 9780849315251

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Charles Hansen began his work with solvents in 1962, and almost immediately began producing new and groundbreaking results. Since then, his Hansen Solubility Parameters have been extensively used and proven valuable to a variety of industries, including coatings, adhesives, plastics, protective clothing, and environmental protection. They allow correlations and systematic comparisons previously not possible, such as polymer solubility, swelling and permeation, surface wetting and dewetting, the solubility of organic salts, and many biological applications. Until now, however, their seemingly universal ability to predict molecular affinities has been generally taken as semiempirical. Moving beyond the Hildebrand and Flory theories, Hansen found that his approach not only quantitatively describes hydrogen bonding and polar bonding in many types of systems, but in fact agrees with and extends the very general Prigogine theory. This explains why the correlations all seem to fit with an apparently "universal" 4: it results from the validity of applying the geometric mean rule to describe dispersion, permanent dipole-permanent dipole, and hydrogen bonding interaction in mixtures of unlike molecules. Hansen Solubility Parameters provides new tables of previously unpublished correlations and parameters. The author illuminates his text with practical examples related to coatings, biological systems, pigments, and fibers, and takes a general approach that makes this reference ideal for predicting compatibility, adsorption on surfaces, orientation toward materials of similar affinities (self-assembly), and other phenomena associated with solubility and affinity. Chemists, chemical engineers, and biochemists will find this book-the collected work and experience of the father of its concept-intriguing for its theory and invaluable for its data.