Author :
Publisher :
Page : 0 pages
File Size : 36,64 MB
Release : 1994
Category :
ISBN :
[PDF] Fibrosis In Disease eBook
Fibrosis In Disease Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Fibrosis In Disease book. This book definitely worth reading, it is an incredibly well-written.
Fibrosis in Disease
Monte S. Willis
Author : Monte S. Willis
Publisher : Springer
Page : 471 pages
File Size : 11,90 MB
Release : 2018-11-10
Category : Medical
ISBN : 3319981439
Fibroproliferative diseases are a broad spectrum of entities from organ-specific involvement (e.g., pulmonary, heart, liver, and kidney fibrosis) to multi-system diseases such as systemic sclerosis and sclerodermatous graft vs. host disease. These diseases also encompass pathophysiologies not readily recognizably related, such as macular degeneration and cancer metastasis. Fibroproliferative diseases are a leading cause of morbidity and mortality and can affect all tissues and organ systems. Remarkable progress in elucidating the pathogenesis of these common diseases with fibrotic components, including the critical roles of myofibroblasts and the molecular mechanisms driving the transcriptional activation involved in the induction of fibrosis. As the importance of these processes is realized in the long-term recovery and treatment of diseases, effective anti-fibrotic therapies targeting the underlying ongoing disease processes are lacking. The complexity of discovering and applying therapies to fibroproliferative disease may be due to the diversity of the systems the pathogenesis of disease itself involves. By nature, fibroproliferative diseases are interdisciplinary, involving multiple cell types (organ-specific epithelial cells), immune cells, endothelial cells, and fibroblasts. Bone marrow, cytokines, and organ-specific pathologies further speckle both the clinical and scientific disciplines in such a way that communication is often limited to the clinical or scientific tribes we live in, despite the greatest access to information known to man available today. Therefore, the primary focus of this text is to bring together authors from a diversity of both clinical, scientific, and therapeutic backgrounds for readers to more fully appreciate that fantastic platform that is available to build upon to lessen the isolation of the clinical and scientific disciplines. With advances in the discovery of pre-clinical therapeutic targets (at least 20+ to date) involving TGF-beta (and other cytokines), transcription factors, and downstream kinases, it’s important to both recognize the broader impact and potential opportunities that exist even today. This book will serve as a state-of-the-art resource for physicians and translational medical researchers alike who are interested in the rapidly evolving field of fibroproliferative diseases. The book will provide new insight into the fundamental mechanisms of classic fibrotic pathophysiologic processes like myocardial infarction, idiopathic pulmonary fibrosis, chronic kidney disease, wound healing, and systemic sclerosis. It will also highlight the many new areas of therapeutic investigation currently underway. Lastly, we will touch upon newly emerging fields investigating the role of fibrosis in macular degeneration and cancer metastasis. The chapters will be written by established experts in their fields, including clinicians (cardiologists, cardiovascular surgeons, pathologists, and general practitioners) and translational biomedical researchers in a wide range of disciplines. However, the material will certainly have a broader audience including medical residents, fellows, and general practitioners as well as M.D. or Ph.D. post-doctoral research fellows. While comprehensive, we'll attempt to present the material in a manner that simplifies the complex pathophysiologic mechanisms that underlie common fibroproliferative diseases while making it appealing to a broad audience.
Idiopathic Pulmonary Fibrosis
Keith C. Meyer
Author : Keith C. Meyer
Publisher : Springer Science & Business Media
Page : 457 pages
File Size : 21,94 MB
Release : 2013-10-16
Category : Medical
ISBN : 1627036822
Idiopathic Pulmonary Fibrosis: A Comprehensive Clinical Guide delivers a concise review of our current understanding of disease pathogenesis and provides current evidence in the medical literature regarding its diagnosis and management. Each chapter includes key points and a summary aiming to update clinicians about various issues concerning the diagnosis and management of IPF. In addition to outlining the current state of knowledge, each chapter also provides a summary of ongoing research and identifies the needs for future research in the field. Idiopathic Pulmonary Fibrosis: A Comprehensive Clinical Guide is an important new text that provides its readers with a better understanding of the pathobiology and natural history of IPF as it continues to evolve.
Interstitial Lung Disease E-Book
Harold R Collard
Author : Harold R Collard
Publisher : Elsevier Health Sciences
Page : 204 pages
File Size : 23,32 MB
Release : 2017-02-18
Category : Medical
ISBN : 032348025X
Clinically focused and designed to provide a to-the-point overview, Interstitial Lung Disease, by Drs. Talmadge King, Harold Collard, and Luca Richeldi, bring you up to date with increased understanding, new treatment protocols, and recent advances in the field. Written by contributing specialists who are global experts in their respective areas, this one-stop reference provides pulmonologists, intensivists, internal medicine physicians, and researchers with a dependable source of information on current treatment options and patient care. • Evidence for current treatment options for interstitial pneumonia, idiopathic pulmonary fibrosis, and smoking-related interstitial lung diseases. • Approach to diagnosis of interstitial lung diseases, such as sarcoidosis, hypersensitivity pneumonitis, and Churg-Strauss syndrome. • Genetic markers for inherited interstitial lung diseases such as dyskeratosis congenita, tuberous sclerosis/LAM, and hyper-IgE syndrome.
Idiopathic Pulmonary Fibrosis
Jeffrey Swigris
Author : Jeffrey Swigris
Publisher : Elsevier Health Sciences
Page : 350 pages
File Size : 10,79 MB
Release : 2018-07-25
Category : Medical
ISBN : 0323544320
Designed with the practicing clinician in mind, Idiopathic Pulmonary Fibrosis provides a succinct, easy-to-digest overview of this challenging condition in which the cause of thickening lung tissue is unknown. This concise resource by Drs. Kevin K. Brown and Jeff Swigris provides essential information for the physician who sees pulmonary fibrosis patients, including epidemiology, genetics and biomarkers, pathology, diagnosis, disease monitoring, and therapeutics intended to improve the patient’s lifespan and quality of life.
Idiopathic Pulmonary Fibrosis
Joseph P. Lynch
Author : Joseph P. Lynch
Publisher : CRC Press
Page : 800 pages
File Size : 28,80 MB
Release : 2003-12-18
Category : Medical
ISBN : 0203913442
A discussion of the epidemiology, clinical features, and differential diagnoses of idiopathic pulmonary fibrosis (IPF). Key topics include the role of polymorphonuclear leukocytes in the pathogenesis of pulmonary fibrosis, and current treatment options, including medical therapy and lung transplantation.
Idiopathic Pulmonary Fibrosis
Ulrich Costabel
Author : Ulrich Costabel
Publisher : European Respiratory Society
Page : 292 pages
File Size : 21,63 MB
Release : 2016-03-01
Category : Medical
ISBN : 1849840687
Idiopathic pulmonary fibrosis (IPF) is a steadily progressive and ultimately fatal disease of unknown origin. Recent years have seen advances in our understanding of IPF and a number of guidelines have been published. But many questions remain unanswered, particularly surrounding probable versus definite IPF. This Monograph aims to discuss the latest achievements in IPF, and covers key diagnostic issues, staging of the disease, complications and comorbidities, treatment, unmet patient needs and perspectives for the future. This book will be of interest to all clinicians and researchers in this area.
Idiopathic Pulmonary Fibrosis
Keith C. Meyer
Author : Keith C. Meyer
Publisher : Springer
Page : 475 pages
File Size : 19,47 MB
Release : 2018-12-14
Category : Medical
ISBN : 3319999753
This book is a comprehensive guide to our current understanding of idiopathic pulmonary fibrosis (IPF), its disease pathogenesis, genetic underpinnings, diagnosis, and management. Since the first edition, many new developments have occurred in the understanding and management of this serious disease, revising our understanding of how it presents, manifests, and reacts to certain treatments. This second edition is fully updated with six new chapters by our team of international, expert authors. New topics include: classification of interstitial lung disease, pulmonary function tests in IPF, biomarkers, clinical phenotypes, mimics, and a discussion of clinical trials. Each chapter additionally includes a brief summary of ongoing research and potential future directions. Idiopathic Pulmonary Fibrosis: A Comprehensive Clinical Guide, Second Edition is an invaluable resource for clinicians who desire a deeper understanding of IPF in order to better help their patients.
Fibrocytes in Health and Disease
Richard Bucala
Author : Richard Bucala
Publisher : World Scientific
Page : 335 pages
File Size : 37,67 MB
Release : 2012
Category : Medical
ISBN : 9814343722
This volume provides a comprehensive and multidisciplinary overview of fibrocytes, written by the main researchers in the field. It is aimed at a broad audience of scientists and clinicians with an interest in the role of circulating fibrocytes in the etiopathogenesis of different fibrosing disorders, atherosclerosis, autoimmunity, and cancer.
Guide to Clinical Management of Idiopathic Pulmonary Fibrosis
Steven D Nathan
Author : Steven D Nathan
Publisher : Springer
Page : 135 pages
File Size : 10,72 MB
Release : 2016-07-27
Category : Medical
ISBN : 3319327941
This clinically focused pocket guide offers a concise yet complete overview of idiopathic pulmonary fibrosis, covering the most recent information on aspects such as pathophysiology, management, treatment, and clinical trials. The text is easily accessible and offers pulmonologists and other health care professionals with an excellent quick reference tool. Full color images and figures enhance and summarize key aspects of the text. Idiopathic pulmonary fibrosis is a condition that affects the alveoli and leads to serious lung damage, and the idiopathic nature of this disease means that the origin or cause is unknown. This disease is relatively rare, affecting 3 in 10,000 people, but it is becoming more common. Physicians should be aware of the early stages and symptoms of this disease so management strategies can be implemented quickly, and the best treatment can be administered.