[PDF] Experimental And Clinical Evidence Of The Neuropathology Of Parkinsons Disease eBook

Author : Draoui, Ahmed
Publisher : IGI Global
Page : 475 pages
File Size : 45,4 MB
Release : 2023-08-04
Category : Medical
ISBN : 1668451573

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Parkinson’s disease is the second most common neurodegenerative disorder in the world after Alzheimer’s disease. Thanks to the pioneering works of Arvid Carlson in the 20th century identifying dopamine as the main neurochemical agent involved in Parkinson’s disease’s onset and progress, our understanding of the neuropathology has increased. The elaboration of L-Dopa as the first pharmacological treatment approach has brought new hope for curing or at least slowing the neurodegenerative progress and the decline of motor and cognitive functions in Parkinson’s disease patients. To date, imaging techniques along with genetic and biochemical tools have allowed scientists and clinicians to predict and diagnose the disease several years prior to the motor disorder’s appearance. Experimental and Clinical Evidence of the Neuropathology of Parkinson’s Disease sheds light on the history of Parkinson’s disease as well as the recent literature on the epidemiological data worldwide including the prevalence of the disease, the morbimortality rates, and the sex dimorphism and aging components. It addresses the current neuropathological evidence of Parkinson’s disease, including the latest discoveries in terms of neuropathology and treatments available or under clinical trials with the efficacy and limitations of each. Covering topics such as epidemiology, stem cells, and neuropathology, this premier reference source is an excellent resource for clinicians, physicians, epidemiologists, neuroscientists, microbiologists, biochemists, pharmacologists, toxicologists, medical professionals, nurses, medical students and educators, librarians, researchers, and academicians.

Author : Jonas H. Ellenberg
Publisher : CRC Press
Page : 600 pages
File Size : 21,78 MB
Release : 1995-03-01
Category : Medical
ISBN : 9780824788230

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This comprehensive reference provides a detailed overview of current concepts regarding the cause of Parkinson's disease-emphasizing the issues involved in the design, implementation, and analysis of epidemiological studies of parkinsonism.

Author : Frank Clifford Rose
Publisher : Demos Medical Publishing
Page : 232 pages
File Size : 14,55 MB
Release : 1987
Category : Medical
ISBN :

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This volume surveys advances that have occured in the last five years. The increased understanding in the neuropathology and neurophysiology of the disease are discussed as well as its history, new drug therapy and the possibility that transplantation of brain cells will prove an effective remedy.

Author : Franz Hefti
Publisher : Springer Science & Business Media
Page : 225 pages
File Size : 35,13 MB
Release : 2012-12-06
Category : Science
ISBN : 1461307597

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In the past five years significant progress has been made in our basic and clinical under standing of Parkinson's disease. The discovery that MPTP, a relatively simple molecule, is able to induce parkinsonism in otherwise healthy adult humans, and the recent interest in the possibility of "transplantation" procedures as a therapeutic modality in the treatment of Parkin son's disease have generated enormous interest in research related to Parkinson's disease. In this setting, the National Parkinson Foundation decided to organize a research meeting to bring together scientists actively engaged in research relevant to the study of Parkinson's disease, to accelerate its progress and to promote an exchange of ideas. This meeting took place in Janu ary 1988 at Key Biscayne, Florida. It was decided to publish the proceedings ofthis meeting to allow rapid documentation of the participants current findings and views regarding this rapidly of this volume follows the organization of the meeting and begins evolving field. The structure with a clinical and neuropathological review of current knowledge regarding Parkinson's dis ease. Since dopaminergic neurons playa major role in the pathophysiology of the disease, many of the contributions relate to some aspects of dopaminergic function including localiza tion, regulation, and pharmacology of dopamine receptors. A special effort has been made to provide a summary of the present knowledge of the cellular biology of the dopaminergic neurons.

Author : Colin R Martin
Publisher : Academic Press
Page : 1548 pages
File Size : 35,77 MB
Release : 2020-12-21
Category : Medical
ISBN : 0128159596

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The Neuroscience of Parkinson’s Disease (two volume set) provides a single source of material covering different scientific domains of neuropathology underlying this condition. The book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, imaging, assessments, and treatment regimens. The book also fills a much-needed gap as a "one-stop" synopsis of everything to do with the neurology and neuroscience related to Parkinson’s disease—from chemicals and cells to individuals. It is an invaluable resource for neuroscientists, neurologists, and anyone in the field. Offers the most comprehensive coverage of a broad range of topics related to Parkinson's disease Serves as a foundational collection for neuroscientists and neurologists on the biology of disease and brain dysfunction Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding Features preclinical and clinical studies to help researchers map out key areas for research and further clinical recommendations Serves as a "one-stop" source for everything you need to know about Parkinson’s disease

Author : Colin R Martin
Publisher : Academic Press
Page : 784 pages
File Size : 15,77 MB
Release : 2020-08-13
Category : Medical
ISBN : 0128159472

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Diagnosis and Management in Parkinson's Disease: The Neuroscience of Parkinson’s, Volume 1 provides a single source of material covering different scientific domains of neuropathology underlying this condition. The book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, imaging, assessments, and treatment regimens. It fills a much-needed gap as a "one-stop" synopsis of everything concerning the neurology and neuroscience related to Parkinson’s disease, from chemicals and cells to individuals. The book is an invaluable resource for neuroscientists, neurologists, and anyone in the field. Offers the most comprehensive coverage of a broad range of topics related to Parkinson's disease Serves as a foundational collection for neuroscientists and neurologists on the biology of disease and brain dysfunction Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding Features preclinical and clinical studies to help researchers map out key areas for research and further clinical recommendations Serves as a "one-stop" source for everything you need to know about Parkinson’s disease

Author : Cristian Falup-Pecurariu
Publisher : Academic Press
Page : 314 pages
File Size : 28,3 MB
Release : 2021-09-28
Category : Technology & Engineering
ISBN : 0323851231

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Autonomic dysfunction is one of the most prevalent non-motor symptoms that occurs in Parkinson’s disease. Autonomic Dysfunction in Parkinson's Disease provides up to date information on this important topic, which affects quality of life of these patients. This include a large number of domains: orthostatic hypotension, excessive sweating, dry eyes, constipation, weight loss, increased sensitivity to heat and cold, sexual dysfunction. Provides comprehensive reviews on different topics of autonomic dysfunction in Parkinson’s disease Each chapter covers a specific autonomic symptom: classification, assessment, treatment Presents the newest information on each autonomic symptom in Parkinson’s disease

Author : Peter Riederer
Publisher : Springer Science & Business Media
Page : 484 pages
File Size : 10,33 MB
Release : 2006-11-23
Category : Medical
ISBN : 3211452958

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This book gives a comprehensive overview on current clinical and basic research issues related to Parkinson’s disease and its related disorders. The book is the result of the 16th International Congress of Parkinson’s Disease and Related disorders congress 2005. Its contents are suitable for neurologists, psychiatrists, neurosurgeons, basic researchers, geneticians and patients as well as their relatives.