[PDF] Dynamics Of Biological Macromolecules As Probed By Nmr eBook

Author : Anirban Bhunia
Publisher : Royal Society of Chemistry
Page : 733 pages
File Size : 22,68 MB
Release : 2022-08-17
Category : Science
ISBN : 1839162090

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Providing a comprehensive amalgamation of the scattered knowledge of how to apply high-resolution NMR techniques to biomolecular systems, this book will break down the conventional stereotypes in the use of NMR for structural studies.

Author : John L. Markley
Publisher : Oxford University Press
Page : 375 pages
File Size : 44,37 MB
Release : 1997-01-30
Category : Science
ISBN : 0195357426

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This book presents a critical assessment of progress on the use of nuclear magnetic resonance spectroscopy to determine the structure of proteins, including brief reviews of the history of the field along with coverage of current clinical and in vivo applications. The book, in honor of Oleg Jardetsky, one of the pioneers of the field, is edited by two of the most highly respected investigators using NMR, and features contributions by most of the leading workers in the field. It will be valued as a landmark publication that presents the state-of-the-art perspectives regarding one of today's most important technologies.

Author :
Publisher : Elsevier
Page : 513 pages
File Size : 34,94 MB
Release : 2001-07-12
Category : Science
ISBN : 0080496881

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This volume and its companion, Volume 339, supplement Volumes 176, 177, 239, and 261. Chapters are written with a "hands-on" perspective. That is, practical applications with critical evaluations of methodologies and experimental considerations needed to design, execute, and interpret NMR experiments pertinent to biological molecules.

Author : Andrew J. Dingley
Publisher : IOS Press
Page : 488 pages
File Size : 15,38 MB
Release : 2011
Category : Medical
ISBN : 1607506947

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Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful technique for characterization of biomolecular structures at atomic resolution in the solution state. This timely book, entitled "Biomolecular NMR Spectroscopy," focuses on the latest state-of-the-art NMR techniques for characterization of biological macromolecules in the solid and solution state. The editors, Dr. Andrew Dingley (University of Auckland, New Zealand) and Dr. Steven Pascal (Massey University, New Zealand) have organized the book into four sections, covering the following topics: sample preparation, structure and dynamics of proteins, structure and dynamics of nucleic acids and protein-nucleic acid complexes, and rapid and hybrid techniques--

Author : Ye Tian
Publisher :
Page : 147 pages
File Size : 36,63 MB
Release : 2010
Category : DNA-protein interactions
ISBN : 9781124263557

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Another practice of NMR in my work is using 31 P Dynamic NMR to characterize the backbone conformation and dynamics in DNA Dickerson Dodecamer. The results confirm solid-state 2 H-NMR experiments showing that the C3pG4 and C9pG10 steps experience unique dynamics. And cytosine methylation has significant impact on the local dynamics. The results also show that 31 P Dynamic NMR is an efficient way to extract DNA backbone dynamic information, and provide detail knowledge to study DNA-protein interactions.

Author :
Publisher : Academic Press
Page : 670 pages
File Size : 22,89 MB
Release : 2005-05-04
Category : Science
ISBN : 0080549470

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The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences. Nuclear Magnetic Resonance of Biological Macromolecules, Part C is written with a "hands-on" perspective. That is, practical applications with critical evaluations of methodologies and experimental considerations needed to design, execute, and interpret NMR experiments pertinent to biological molecules. * One of the most highly respected publications in the field of biochemistry since 1955 * Frequently consulted, and praised by researchers and reviewers alike * Truly an essential publication for anyone in any field of the life sciences

Author : Chariklia I. Stassinopoulou
Publisher : Springer Science & Business Media
Page : 367 pages
File Size : 44,96 MB
Release : 2013-06-29
Category : Science
ISBN : 3642791581

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Provided here are the latest techniques of NMR as applied to the study of proteins, carbohydrates and nucleic acids. The first chapters are devoted to an introduction to NMR and parameters related to molecular structure and molecular interactions. NMR experiments from basic 1D to 2D, 3D and 4D, used in combination with isotopically labelled molecules, are described and a general strategy is presented for biomacromolecular structure determination. Subsequent chapters deal with more advanced principles and techniques and their applications to structural and dynamic processes involving biomacromolecules in solution. Advanced results on peptide, protein, oligosaccharide and nucleic acid structure and recognition are presented.

Author : Michaeleen Doucleff
Publisher : Springer Science & Business Media
Page : 166 pages
File Size : 23,79 MB
Release : 2011-01-03
Category : Science
ISBN : 3642162517

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Steering clear of quantum mechanics and product operators, "Pocket Guide to Biomolecular NMR" uses intuitive, concrete analogies to explain the theory required to understand NMR studies on the structure and dynamics of biological macromolecules. For example, instead of explaining nuclear spin with angular momentum equations or Hamiltonians, the books describes nuclei as "bells" in a choir, ringing at specific frequencies depending on the atom type and their surrounding electromagnetic environment.This simple bell analogy, which is employed throughout the book, has never been used to explain NMR and makes it surprisingly easy to learn complex, bewildering NMR concepts, such as dipole-dipole coupling and CPMG pulse sequences. Other topics covered include the basics of multi-dimensional NMR, relaxation theory, and Model Free analysis. The small size and fast pace of “Pocket Guide to Biomolecular NMR” makes the book a perfect companion to traditional biophysics and biochemistry textbooks, but the book's unique perspective will provide even seasoned spectroscopists with new insights and handy “thought” short-cuts.

Author :
Publisher : Academic Press
Page : 544 pages
File Size : 50,14 MB
Release : 2019-01-10
Category : Science
ISBN : 0128167637

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Biological NMR, Part B, the latest release in the Methods of Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Protein methyl labeling, Membrane protein expression – yeast, Protein aromatic labeling, His-tag/Metal contamination, Bicelles, nanodiscs & micelles MP host, PTM – phosphorylation, PTM – lipidation, Screening platform for receptor-ligand discovery, Solution Spectroscopy, Large protein strategies, NUS data collection/analysis, F19 incl. hydration, ODNP - hydration, Reverse micelle - Hydration, Solid State Spectroscopy, SS NMR membrane proteins, SS NMR soluble/aggregate proteins, SS DNP - general, SS NMR nucleic acids, and much more. Authoritative contributors Protocols for state-of-the-art advances Timeliness