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Author : Navneet Kaur Bhogal
Publisher :
Page : pages
File Size : 42,56 MB
Release : 2019
Category :
ISBN :
Author : Viacheslav Nikolaev
Publisher : Springer
Page : 383 pages
File Size : 10,73 MB
Release : 2017-09-19
Category : Medical
ISBN : 3319545795
The book comprehensively presents new findings in cardiovascular research related to signaling microdomains in health and disease. Important second messengers such as cAMP, cGMP, calcium and their role in microdomain signaling are discussed. The book offers and explains methodical approaches and technical ways how to successfully analyze microdomain signaling, also in the context of disease. It further provides scientific perspectives and strategies that are based on the concept of signaling within microdomains and that can revolutionize pharmacology and eventually lead to the effective treatment of cardiovascular diseases in future.This book is written for scientists in cardiovascular research, pharmacology, molecular and cellular biology as well as medical doctors in cardiology, angiology and nephrology.
Author : Thomas Brand
Publisher : MDPI
Page : 307 pages
File Size : 29,41 MB
Release : 2018-07-10
Category : Medical
ISBN : 3038429899
This book is a printed edition of the Special Issue "Cyclic Nucleotide Signaling and the Cardiovascular System" that was published in JCDD
Author : Alexey V. Glukhov
Publisher : Frontiers Media SA
Page : 212 pages
File Size : 16,77 MB
Release : 2020-07-08
Category :
ISBN : 2889638367
Author : XiaoDong Cheng
Publisher : CRC Press
Page : 288 pages
File Size : 42,23 MB
Release : 2021-03-30
Category : Cellular signal transduction
ISBN : 9780367658809
Showcasing the recent progresses of the field, Cyclic Nucleotide Signaling covers the major tools and methodologies used in various areas of research. The majority of the chapters are protocol oriented, with the goal of providing clear directions for laboratory use. Students and investigators new to the field will find this book particularly informative, as will scientists already actively researching nucleotide signaling.
Author : Joseph A. Beavo
Publisher : CRC Press
Page : 728 pages
File Size : 40,49 MB
Release : 2006-12-05
Category : Medical
ISBN : 1420020846
Since the last major compendium dedicated to cyclic nucleotide phosphodiesterases (PDEs) was published over 15 years ago, an enormous amount of progress has occurred in the field. There is great need for a centralized source for key information in this burgeoning and therapeutically important area of medical research. Cyclic Nucleotide Phosph
Author : Michitoshi Inoue
Publisher : Springer Science & Business Media
Page : 330 pages
File Size : 40,3 MB
Release : 2013-11-09
Category : Medical
ISBN : 4431683674
Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.
Author : Ihor Gussak
Publisher : Springer Science & Business Media
Page : 549 pages
File Size : 14,10 MB
Release : 2003-03-13
Category : Medical
ISBN : 1592593623
A comprehensive review of all the latest developments in cardiac electrophysiology, focusing on both the clinical and experimental aspects of ventricular repolarization, including newly discovered clinical repolarization syndromes, electrocardiographic phenomena, and their correlation with the most recent advances in basic science. The authors illuminate the basic electrophysiologic, molecular, and pharmacologic mechanisms underlying ventricular repolarization, relate them to specific disease conditions, and examine the future of antiarrhythmic drug development based on both molecular and electrophysiological properties. They also fully review the clinical presentation and management of specific cardiac repolarization conditions.
Author : José Marín-García
Publisher : Springer Science & Business Media
Page : 511 pages
File Size : 47,74 MB
Release : 2011-06-21
Category : Medical
ISBN : 1441994610
Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology. The heart is both a transmitter and dynamic receptor of a variety of intracellular and extracellular stimuli, playing a critical role of an integrator of diverse signaling mechanisms. Alterations in signaling pathways are contributing factors in the development and progression of a broad spectrum of diseases, ranging from dysrhythmias and atherosclerosis to hypertension and the metabolic syndrome. Targeting specific components of these signaling pathways has been shown to be effective in preclinical studies with significant therapeutic impact. This book brings together current knowledge in cardiovascular cell signal transduction mechanisms, advances in novel therapeutic approaches to improve cardiac function, and discussion of future directions. Presented from a post-genomic perspective, this exciting book introduces important new ideas in cardiovascular systems biology. It is an invaluable reference for cardiology researchers and practitioners.
Author : Md. Shahidul Islam
Publisher : Springer Nature
Page : 1110 pages
File Size : 15,48 MB
Release : 2019-10-23
Category : Medical
ISBN : 3030124576
This volume contains a unique selection of chapters covering a wealth of contemporary topics in this ubiquitous and diverse system of cell signaling. It offers much more than the accessibility and authority of a primary text book, exploring topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future scientific endeavors. The contributions feature material on theoretical and methodological topics as well as related subjects including mathematical modeling and simulations. They examine calcium signaling in a host of contexts, from mammalian cells to bacteria, fruit fly and zebrafish. With much of interest to newcomers to the field as well as seasoned experts, this new publication is both wide-ranging and authoritative. The chapter “Calcium Signaling: From Basic to Bedside” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.